Search Results - "Scindia, Yogesh M"
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Mesangial pathology in glomerular disease: targets for therapeutic intervention
Published in Advanced drug delivery reviews (30-11-2010)“…The glomerulus is the filtration unit of the kidney. Disruption of glomerular function may be caused by primary glomerular pathology or secondary to systemic…”
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Biocompatibility of ferritin-based nanoparticles as targeted MRI contrast agents
Published in Nanomedicine (01-08-2016)“…Abstract Ferritin is a naturally occurring iron storage protein, proposed as a clinically relevant nanoparticle with applications as a diagnostic and…”
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Activation of innate immune responses through Toll-like receptor 3 causes a rapid loss of salivary gland function
Published in Journal of oral pathology & medicine (01-01-2009)“…Background: Recent studies have demonstrated the expression of Toll‐like receptor 3 (TLR3) in salivary glands and epithelial cell lines derived from Sjögren’s…”
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Iron Inhibits the Translation and Activity of the Renal Epithelial Sodium Channel
Published in Biology (Basel, Switzerland) (12-01-2022)“…Hypertension is associated with an increased renal expression and activity of the epithelial sodium channel (ENaC) and iron deficiency. Distal tubules absorb…”
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Metformin Alleviates Diabetes-Associated Hypertension by Attenuating the Renal Epithelial Sodium Channel
Published in Biomedicines (21-01-2023)“…Diabetic nephropathy is the primary cause of morbidity in type 2 diabetes mellitus (T2DM) patients. New data indicate that hypertension, a common comorbidity…”
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Kidney‐Specific BMAL1 Knockout is Protective in High Salt Diet‐Induced Renal Inflammation
Published in The FASEB journal (01-05-2022)“…The circadian clock factor BMAL1, particularly within the kidney, has been shown to influence systemic blood pressure (BP) control. A diet high in salt is…”
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Male kidney-specific BMAL1 knockout mice are protected from K + -deficient, high-salt diet-induced blood pressure increases
Published in American journal of physiology. Renal physiology (01-11-2023)“…The circadian clock protein basic helix-loop-helix aryl hydrocarbon receptor nuclear translocator-like protein 1 (BMAL1) is a transcription factor that impacts…”
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Genetic Complementation Results in Augmented Autoantibody Responses to Lupus-Associated Antigens
Published in The Journal of immunology (1950) (01-09-2009)“…Lupus-prone female New Zealand Mixed (NZM)2328 mice develop high titers of anti-nuclear and anti-dsDNA autoantibodies. Despite high expression of type I IFNs,…”
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Hepcidin Deficiency Exacerbates Renal Pathology in Disseminating Candidiasis: TH-PO135
Published in Journal of the American Society of Nephrology (01-11-2022)Get full text
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Activation of innate immunity accelerates sialoadenitis in a mouse model for Sjögren's syndrome-like disease
Published in Oral diseases (01-11-2011)“…Oral Diseases (2011) 17, 801–807 Objective: Sjögren’s syndrome is a chronic autoimmune disorder characterized by progressive lymphocytic infiltration within…”
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Mesangial pathology in glomerular disease: targets for therapeutic intervention: DRUG TARGETING TO THE KIDNEY
Published in Advanced drug delivery reviews (2010)Get full text
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