Search Results - "Scibior‐Bentkowska, Dorota"
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DNA methylation testing with S5 for triage of high‐risk HPV positive women
Published in International journal of cancer (01-10-2022)“…Methylation of host and viral genes is promising for triage of women with high‐risk human papillomavirus infections (hrHPV). Using a population‐based sample of…”
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Long-term prediction by DNA methylation of high-grade cervical intraepithelial neoplasia: Results of the ARTISTIC cohort
Published in International journal of cancer (01-07-2024)“…Methylation markers have shown potential for triaging high-risk HPV-positive (hrHPV+) women to identify those at increased risk of invasive cervical cancer…”
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Validation of a DNA methylation HPV triage classifier in a screening sample
Published in International journal of cancer (01-06-2016)“…High‐risk human papillomavirus (hrHPV) DNA tests have excellent sensitivity for detection of cervical intraepithelial neoplasia 2 or higher (CIN2+). A drawback…”
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Low methylation marker levels among human papillomavirus-vaccinated women with cervical high-grade squamous intraepithelial lesions
Published in International journal of cancer (01-11-2024)“…Cervical cancer screening programs, including triage tests, need redesigning as human papillomavirus (HPV)-vaccinated women are entering the programs…”
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A DNA methylation classifier of cervical precancer based on human papillomavirus and human genes
Published in International journal of cancer (15-09-2014)“…Testing for high‐risk (hr) types of human papillomavirus (HPV) is highly sensitive as a screening test of high‐grade cervical intraepithelial neoplastic…”
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Clinical performance of methylation as a biomarker for cervical carcinoma in situ and cancer diagnosis: A worldwide study
Published in International journal of cancer (15-01-2022)“…The shift towards primary human papillomavirus (HPV)‐based screening has necessitated the search for a secondary triage test that provides sufficient…”
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Elevated methylation of HPV16 DNA is associated with the development of high grade cervical intraepithelial neoplasia
Published in International journal of cancer (15-03-2013)“…We explored the association of human papillomavirus type 16 (HPV16) DNA methylation with age, viral load, viral persistence and risk of incident and prevalent…”
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HPV16 L1 and L2 DNA methylation predicts high‐grade cervical intraepithelial neoplasia in women with mildly abnormal cervical cytology
Published in International journal of cancer (01-08-2013)“…DNA methylation changes in human papillomavirus type 16 (HPV16) DNA are common and might be important for identifying women at increased risk of cervical…”
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Methylation of viral and host genes and severity of cervical lesions associated with human papillomavirus type 16
Published in International journal of cancer (15-03-2015)“…Methylation of human papillomavirus (HPV) and host genes may predict cervical cancer risk. We examined the methylation status of selected sites in HPV16 and…”
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HPV33 DNA methylation measurement improves cervical pre-cancer risk estimation of an HPV16, HPV18, HPV31 and \textit{EPB41L3} methylation classifier
Published in Cancer biomarkers : section A of Disease markers (21-09-2015)“…Persistent infection %by with high risk human papillomavirus (hrHPV) types causes cervical cancer but most women who test positive are at very low risk of…”
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Credentialing of DNA methylation assays for human genes as diagnostic biomarkers of cervical intraepithelial neoplasia in high-risk HPV positive women
Published in Gynecologic oncology (01-03-2014)“…Abstract Objective Testing for high risk human papillomavirus (HR-HPV) is increasing; however due to limitations in specificity there remains a need for better…”
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Clinical performance of methylation as a biomarker for cervical carcinoma insitu and cancer diagnosis: A worldwide study
Published in International journal of cancer (01-01-2022)“…The shift towards primary human papillomavirus (HPV)‐based screening has necessitated the search for a secondary triage test that provides sufficient…”
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A comparison of methylation levels in HPV18, HPV31 and HPV33 genomes reveals similar associations with cervical precancers
Published in Journal of clinical virology (01-03-2014)“…Abstract Background High risk human papillomavirus (HR-HPV) infection is common and only a small minority of infections become persistent and lead to cervical…”
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Cancer cells and oxidative stress
Published in Postȩpy higieny i medycyny doświadczalnej (23-02-2009)“…Reactive oxygen species (ROS) formation are a constant element of a cell's oxygen metabolism. They are its normal products and in physiological concentrations…”
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Methylation estimates the risk of precancer in HPV-infected women with discrepant results between cytology and HPV16/18 genotyping
Published in Clinical epigenetics (12-10-2019)“…Vigilant management of women with high-risk human papillomavirus (hrHPV) is necessary in cancer screening programs. To this end, we evaluated the performance…”
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Changes of the glutathione enzymatic redox system in human gastrointestinal tract tumours
Published in Archives of medical science (01-12-2009)“…Introduction: Glutathione (GSH) and GSH-dependent enzymes - glutathione peroxidase (GSHPx), glutathione S-transferase (GST) and glutathione reductase (GSHR) -…”
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Assessment of lipid peroxidation level in serum of patients with gastrointestinal tract tumors
Published in Wiadomości lekarskie (1960) (2010)“…Clinical and experimental studies indicate oxygen free radicals and their reactive derivatives participation in formation of chronic inflammation states, which…”
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Quantitative DNA methylation and recurrence of breast cancer: a study of 30 candidate genes
Published in Cancer biomarkers : section A of Disease markers (01-01-2012)“…The need for new prognostic factors in breast cancer is ever increasing as breast cancer management evolves. Aberrant DNA methylation plays a pivotal role in…”
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Lipid peroxidation level in gastrointestinal tract tumors
Published in Polski merkuriusz lekarski (01-11-2010)“…Oxygen free radicals and their reactive derivatives participate in formation of chronic inflammation states, which facilitate development of gastrointestinal…”
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Protein level of transcription factors AP-1 and NF-kappaB in selected human gastrointestinal tract tumors
Published in Polski merkuriusz lekarski (01-12-2008)“…Transcription factors AP-1 and NF-kappaB control important cell processes like proliferation, apoptosis and differentiation. Disturbance of this processes is…”
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