Search Results - "Scialpi, Rosanna"
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The ‘speck’-tacular oversight of the NLRP3-pyroptosis pathway on gastrointestinal inflammatory diseases and tumorigenesis
Published in Journal of biomedical science (27-10-2023)“…The NLRP3 inflammasome is an intracellular sensor and an essential component of the innate immune system involved in danger recognition. An important hallmark…”
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2
Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models
Published in Journal of experimental & clinical cancer research (08-08-2023)“…Autotaxin (ATX) is a secreted enzyme that converts lysophosphatidylcholine to lysophosphatidic acid (LPA). LPA stimulates cell proliferation and migration and…”
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3
Proteoglycan-4 is correlated with longer survival in HCC patients and enhances sorafenib and regorafenib effectiveness via CD44 in vitro
Published in Cell death & disease (16-11-2020)“…Sorafenib and regorafenib administration is among the preferential approaches to treat hepatocellular carcinoma (HCC), but does not provide satisfactory…”
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Correction: Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models
Published in Journal of experimental & clinical cancer research (18-08-2023)Get full text
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5
Cyclizations of N-Stannylaminyl Radicals onto Nitriles
Published in Organic letters (05-02-2004)“…Stannylaminyl radicals derived from radical reactions of Bu3SnH with azidoalkylmalononitriles exhibit highly efficient 5- and 6-exo cyclization onto either…”
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Laminin-332 γ2 Monomeric Chain Promotes Adhesion and Migration of Hepatocellular Carcinoma Cells
Published in Cancers (06-01-2023)“…Extracellular matrix (ECM) has a well-recognized impact on the progression of solid tumors, including hepatocellular carcinoma (HCC). Laminin 332 (Ln332) is a…”
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7
Proteoglycans in Cancer: Friends or Enemies? A Special Focus on Hepatocellular Carcinoma
Published in Cancers (09-04-2022)“…Proteoglycans are a class of highly glycosylated proteins expressed in virtually all tissues, which are localized within membranes, but more often in the…”
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Inorganic Polyphosphate Promotes Colorectal Cancer Growth via TRPM8 Receptor Signaling Pathway
Published in Cancers (28-09-2024)“…Colorectal cancer (CRC) is characterized by a pro-inflammatory microenvironment and features high-energy-supply molecules that assure tumor growth. A still…”
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Reaction of Azides with Dichloroindium Hydride: Very Mild Production of Amines and Pyrrolidin-2-imines through Possible Indium−Aminyl Radicals
Published in Organic letters (08-06-2006)“…Organic azides are easily reduced to the corresponding amines by reaction with dichloroindium hydride under very mild conditions and in a highly chemoselective…”
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Radical Reduction of Aromatic Azides to Amines with Triethylsilane
Published in Journal of organic chemistry (21-07-2006)“…Aromatic azides are inert toward triethylsilane under thermal conditions in the presence of a radical initiator, but in the presence of additional catalytic…”
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11
Generation and Cyclization of Unsaturated Carbamoyl Radicals Derived from S-4-Pentynyl Carbamothioates under Tin-Free Conditions
Published in Journal of organic chemistry (14-04-2006)“…The radical reaction of benzenethiol with S-4-pentynyl carbamothioates provides a valuable protocol for the tin-free generation of carbamoyl radicals, which…”
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12
Smiles rearrangement for the synthesis of 5-amino-substituted [1]benzothieno[2,3- b ]pyridine
Published in Tetrahedron (15-09-2003)Get full text
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13
Radical Reduction of Aromatic Azides to Amines with Tributylgermanium Hydride
Published in Journal of organic chemistry (06-01-2006)“…Aromatic azides are inert toward tributylgermanium hydride under thermal conditions in the absence and in the presence of a radical initiator but in the…”
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14
A Novel Tin-Free Procedure for Alkyl Radical Reactions
Published in Angewandte Chemie International Edition (05-07-2004)“…Desulfuration as a source of alkyl radicals: The addition of alkylsulfanyl radicals to isocyanides gives the corresponding alkyl radicals. This methodology can…”
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Thermal Reactions of Tributyltin Hydride with α-Azido Esters: Unexpected Intervention of Tin Triazene Adducts under Both Nonradical and Radical Conditions
Published in Journal of organic chemistry (15-04-2005)“…Thermal reaction of various α-azido esters with Bu3SnH in refluxing benzene results in smooth production of 3-(tributylstannyl)-1-triazene adducts affording…”
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16
A Novel Tin-Free Procedure for Alkyl Radical Reactions
Published in Angewandte Chemie (05-07-2004)“…Durch Entschwefelung zu Alkylradikalen: Die Zugabe von Alkylsulfanylradikalen zu Isocyaniden liefert die entsprechenden Alkylradikale. Dieses Verfahren kann…”
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17
A Novel Tin‐Free Procedure for Alkyl Radical Reactions
Published in Angewandte Chemie (05-07-2004)Get full text
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