Search Results - "Schwitalle, Yvette"

Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers by Schwitalle, Yvette, Kloor, Matthias, Eiermann, Susanne, Linnebacher, Michael, Kienle, Peter, Knaebel, Hanns Peter, Tariverdian, Mirjam, Benner, Axel, von Knebel Doeberitz, Magnus

“…Background & Aims: Colorectal cancers (CRC) associated with the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome display high-level microsatellite…”
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The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers by Woerner, Stefan M., Kloor, Matthias, Schwitalle, Yvette, Youmans, Hanni, Doeberitz, Magnus von Knebel, Gebert, Johannes, Dihlmann, Susanne

“…Mismatch repair (MMR) deficiency is a major mechanism of colorectal tumorigenesis that is observed in 10–15% of sporadic colorectal cancers and those…”
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Beta2‐microglobulin mutations in microsatellite unstable colorectal tumors by Kloor, Matthias, Michel, Sara, Buckowitz, Boris, Rüschoff, Josef, Büttner, Reinhard, Holinski‐Feder, Elke, Dippold, Wolfgang, Wagner, Rudolf, Tariverdian, Mirjam, Benner, Axel, Schwitalle, Yvette, Kuchenbuch, Beate, von Knebel Doeberitz, Magnus

“…Defects of DNA mismatch repair (MMR) cause the high level microsatellite instability (MSI‐H) phenotype. MSI‐H cancers may develop either sporadically or in the…”
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Reply by Schwitalle, Yvette, von Knebel Doeberitz, Magnus, Kloor, Matthias

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Reply by Schwitalle, Yvette, von Knebel Doeberitz, Magnus, Kloor, Matthias

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WT1 is a tumor‐associated antigen in colon cancer that can be recognized by in vitro stimulated cytotoxic T cells by Koesters, Robert, Linnebacher, Michael, Coy, Johannes F., Germann, Anja, Schwitalle, Yvette, Findeisen, Peter, von Knebel Doeberitz, Magnus

“…The Wilms' tumor suppressor gene (WT1) has been shown to be overexpressed in acute and chronic leukemias and in a variety of solid human malignancies,…”
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Immunogenic peptides generated by frameshift mutations in DNA mismatch repair-deficient cancer cells by Schwitalle, Yvette, Linnebacher, Michael, Ripberger, Eva, Gebert, Johannes, von Knebel Doeberitz, Magnus

“…About 15% of all human colorectal, gastric, and endometrial tumors, and the majority of tumors in patients suffering from hereditary nonpolyposis colorectal…”
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Tetranucleotide repeats in coding regions : no evidence for involvement in EMAST carcinogenesis by KLOOR, Matthias, SCHWITALLE, Yvette, VON KNEBEL DOEBERITZ, Magnus, WENTZENSEN, Nicolas

“…Genetic instability is a hallmark of malignancy. In the majority of malignant tumors, chromosomal instability leads to major numerical and structural…”
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Identification of an HLA-A0201-restricted CTL epitope generated by a tumor-specific frameshift mutation in a coding microsatellite of the OGT gene by RIPBERGER, Eva, LINNEBACHER, Michael, SCHWITALLE, Yvette, GEBERT, Johannes, VON KNEBEL DOEBERITZ, Magnus

“…Deficient DNA mismatch repair results in microsatellite instability and might induce shifts of translational reading frames of genes encompassing coding…”
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Generation of RAGE‐1 and MAGE‐9 peptide‐specific cytotoxic T‐Lymphocyte lines for transfer in patients with renal cell carcinoma by Oehlrich, Nicole, Devitt, Gerard, Linnebacher, Michael, Schwitalle, Yvette, Groβkinski, Sonja, Stevanovic, Stefan, Zöller, Margot

“…Renal cell carcinomas (RCCs) are supposed to be immunogenic, and several clinical trials of immunotherapy using tumor lysate‐pulsed dendritic cells (DCs) have…”
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Identification of an HLA-A0201-restricted CTL epitope generated by a tumor-specific frameshift mutation in a coding microsatellite of the OGT gene1 by Ripberger, Eva, Linnebacher, Michael, Schwitalle, Yvette, Gebert, Johannes, Magnus Von Knebel Doeberitz

“…Deficient DNA mismatch repair results in microsatellite instability and might induce shifts of translational reading frames of genes encompassing coding…”
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