Search Results - "Schwier, Elke"

Hemoadsorption with CytoSorb® and the early course of linezolid plasma concentration during septic shock by Köhler, Thomas, Schwier, Elke, Kirchner, Carmen, Winde, Günther, Henzler, Dietrich, Eickmeyer, Claas

“…Hemoadsorption with CytoSorb ® becomes increasingly established in treatment of various, predominantly inflammation-associated diseases. In septic shock,…”
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Therapeutic Modulation of the Host Defense by Hemoadsorption with CytoSorb ® -Basics, Indications and Perspectives-A Scoping Review by Köhler, Thomas, Schwier, Elke, Praxenthaler, Janina, Kirchner, Carmen, Henzler, Dietrich, Eickmeyer, Claas

“…The "normal" immune response to an insult triggers a highly regulated response determined by the interaction of various immunocompetent cells with pro- and…”
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The Association between the rs3747406 Polymorphism in the Glucocorticoid-Induced Leucine Zipper Gene and Sepsis Survivals Depends on the SOFA Score by Rusev, Stefan, Thon, Patrick, Rahmel, Tim, Ziehe, Dominik, Marko, Britta, Nowak, Hartmuth, Ellger, Björn, Limper, Ulrich, Schwier, Elke, Henzler, Dietrich, Ehrentraut, Stefan Felix, Bergmann, Lars, Unterberg, Matthias, Adamzik, Michael, Koos, Björn, Rump, Katharina, SepsisDataNet Nrw Research Group

“…The variability in mortality in sepsis could be a consequence of genetic variability. The glucocorticoid system and the intermediate TSC22D3 gene…”
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AQP3 and AQP9-Contrary Players in Sepsis? by Thon, Patrick, Rahmel, Tim, Ziehe, Dominik, Palmowski, Lars, Marko, Britta, Nowak, Hartmuth, Wolf, Alexander, Witowski, Andrea, Orlowski, Jennifer, Ellger, Björn, Wappler, Frank, Schwier, Elke, Henzler, Dietrich, Köhler, Thomas, Zarbock, Alexander, Ehrentraut, Stefan Felix, Putensen, Christian, Frey, Ulrich Hermann, Anft, Moritz, Babel, Nina, Sitek, Barbara, Adamzik, Michael, Bergmann, Lars, Unterberg, Matthias, Koos, Björn, Rump, Katharina

“…Sepsis involves an immunological systemic response to a microbial pathogenic insult, leading to a cascade of interconnected biochemical, cellular, and…”
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The Aquaporin 3 Polymorphism (rs17553719) Is Associated with Sepsis Survival and Correlated with IL-33 Secretion by Ziehe, Dominik, Marko, Britta, Thon, Patrick, Rahmel, Tim, Palmowski, Lars, Nowak, Hartmuth, von Busch, Alexander, Wolf, Alexander, Witowski, Andrea, Vonheder, Jolene, Ellger, Björn, Wappler, Frank, Schwier, Elke, Henzler, Dietrich, Köhler, Thomas, Zarbock, Alexander, Ehrentraut, Stefan Felix, Putensen, Christian, Frey, Ulrich Hermann, Anft, Moritz, Babel, Nina, Adamzik, Michael, Koos, Björn, Bergmann, Lars, Unterberg, Matthias, Rump, Katharina

“…Sepsis is a common life-threatening disease caused by dysregulated immune response and metabolic acidosis which lead to organ failure. An abnormal expression…”
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Evidence for Sexuality in the Opportunistic Fungal Pathogen Aspergillus fumigatus by Paoletti, Mathieu, Rydholm, Carla, Schwier, Elke U., Anderson, Michael J., Szakacs, George, Lutzoni, François, Debeaupuis, Jean-Paul, Latgé, Jean-Paul, Denning, David W., Dyer, Paul S.

“…Aspergillus fumigatus is a medically important opportunistic pathogen and a major cause of respiratory allergy [ 1]. The species has long been considered an…”
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Isoflurane, like sepsis, decreases CYP1A2 liver enzyme activity in intensive care patients: a clinical study and network model by Köhler, Thomas, Schwier, Elke, Praxenthaler, Janina, Kirchner, Carmen, Winde, Günther, Koos, Björn, Henzler, Dietrich

“…Purpose Liver function of intensive care patients is routinely monitored by static blood pathology. For specific indications, liver specific cytochrome…”
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Profound decrease of liver maximum function capacity test of isoflurane sedated patients: A report of three cases by Schwier, Elke, Kirchner, Carmen, Eickmeyer, Claas, Winde, Günther, Henzler, Dietrich, Köhler, Thomas

“…ABSTRACT LiMAx 13C‐methacetin breath test results should be interpreted with caution in patients sedated with isoflurane. LiMAx 13C‐methacetin breath test…”
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Immunomodulation by Hemoadsorption—Changes in Hepatic Biotransformation Capacity in Sepsis and Septic Shock: A Prospective Study by Praxenthaler, Janina, Schwier, Elke, Altmann, Simon, Kirchner, Carmen, Bialas, Julian, Henzler, Dietrich, Köhler, Thomas

“…Background: Sepsis is often associated with liver dysfunction, which is an indicator of poor outcomes. Specific diagnostic tools that detect hepatic…”
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Case report: Early detection of mesenteric ischemia by intravital microscopy in a patient with septic shock by Praxenthaler, Janina, Kirchner, Carmen, Schwier, Elke, Altmann, Simon, Wittmer, Axel, Henzler, Dietrich, Köhler, Thomas

“…Gut ischemia is a frequent but underdiagnosed complication, especially in critically ill intensive care patients, and represents a special diagnostic challenge…”
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eight-subunit COP9 signalosome with an intact JAMM motif is required for fungal fruit body formation by Busch, Silke, Schwier, Elke U, Nahlik, Krystyna, Bayram, Özür, Helmstaedt, Kerstin, Draht, Oliver W, Krappmann, Sven, Valerius, Oliver, Lipscomb, William N, Braus, Gerhard H

“…Fruit body formation in filamentous fungi is a complex and yet hardly understood process. We show here that protein turnover control is crucial for Aspergillus…”
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Pericarditis Caused by Enterococcus faecium with Acute Liver Failure Treated by a Multifaceted Approach including Antimicrobials and Hemoadsorption by Köhler, Thomas, Pletz, Mathias W., Altmann, Simon, Kirchner, Carmen, Schwier, Elke, Henzler, Dietrich, Winde, Günther, Eickmeyer, Claas

“…Background. Sepsis and septic shock are still life-threatening diseases with a high mortality rate. We report a complex case of peritonitis with pericarditis…”
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Recruitment of the inhibitor Cand1 to the cullin substrate adaptor site mediates interaction to the neddylation site by Helmstaedt, Kerstin, Schwier, Elke U, Christmann, Martin, Nahlik, Krystyna, Westermann, Mieke, Harting, Rebekka, Grond, Stephanie, Busch, Silke, Braus, Gerhard H

“…Cand1 inhibits cullin RING ubiquitin ligases by binding unneddylated cullins. The Cand1 N-terminus blocks the cullin neddylation site, whereas the C-terminus…”
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Dosing of Antimycotic Treatment in Sepsis–Induced Liver Dysfunction by Functional Liver Testing with LiMAx by Köhler, Thomas, Eickmeyer, Claas, Henzler, Dietrich, Schwier, Elke, Sibai, Jasmin, Kirchner, Carmen, Winde, Günther

“…Background. Sepsis-treatment is one of the major challenges in our time. Especially fungal infections play an important role in patient’s morbidity and…”
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Left-sided superior vena cava by Schwier, Elke, Schneider, Arnold, Henzler, Dietrich, Köhler, Thomas

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High-dose CytoSorb hemoadsorption is associated with improved survival in patients with septic shock: A retrospective cohort study by Schultz, Philipp, Schwier, Elke, Eickmeyer, Claas, Henzler, Dietrich, Köhler, Thomas

“…Hemoadsorption with CytoSorb® offers a possible therapeutic approach in septic shock, but modes of application and dosing are still undetermined. Data from…”
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Does adjunctive hemoadsorption with CytoSorb affect survival of COVID-19 patients on ECMO? A critical statement by Köhler, Thomas, Schwier, Elke, Henzler, Dietrich, Eickmeyer, Claas

“…Dear Editor In addition to the comments of Putzu and Schorer [1] concerning the critical use of hemoadsorption in septic shock, we would like to bring some…”
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High expression of L-GILZ transcript variant 1 (GILZ TV 1) is associated with increased 30-day sepsis mortality, and a high expression ratio possibly contraindicates hydrocortisone administration by Rusev, Stefan, Thon, Patrick, Dyck, Birte, Ziehe, Dominik, Rahmel, Tim, Marko, Britta, Palmowski, Lars, Nowak, Hartmuth, Ellger, Björn, Limper, Ulrich, Schwier, Elke, Henzler, Dietrich, Ehrentraut, Stefan Felix, Bergmann, Lars, Unterberg, Matthias, Adamzik, Michael, Koos, Björn, Rump, Katharina

“…Sepsis presents a challenge due to its complex immune responses, where balance between inflammation and anti-inflammation is critical for survival…”
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Assessing SOFA score trajectories in sepsis using machine learning: A pragmatic approach to improve the accuracy of mortality prediction by Palmowski, Lars, Nowak, Hartmuth, Witowski, Andrea, Koos, Björn, Wolf, Alexander, Weber, Maike, Kleefisch, Daniel, Unterberg, Matthias, Haberl, Helge, von Busch, Alexander, Ertmer, Christian, Zarbock, Alexander, Bode, Christian, Putensen, Christian, Limper, Ulrich, Wappler, Frank, Köhler, Thomas, Henzler, Dietrich, Oswald, Daniel, Ellger, Björn, Ehrentraut, Stefan F, Bergmann, Lars, Rump, Katharina, Ziehe, Dominik, Babel, Nina, Sitek, Barbara, Marcus, Katrin, Frey, Ulrich H, Thoral, Patrick J, Adamzik, Michael, Eisenacher, Martin, Rahmel, Tim

“…An increasing amount of longitudinal health data is available on critically ill septic patients in the age of digital medicine, including daily sequential…”
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COP9 signalosome mediates transcriptional and metabolic response to hormones, oxidative stress protection and cell wall rearrangement during fungal development by Nahlik, Krystyna, Dumkow, Marc, Bayram, Özgür, Helmstaedt, Kerstin, Busch, Silke, Valerius, Oliver, Gerke, Jennifer, Hoppert, Michael, Schwier, Elke, Opitz, Lennart, Westermann, Mieke, Grond, Stephanie, Feussner, Kirstin, Goebel, Cornelia, Kaever, Alexander, Meinicke, Peter, Feussner, Ivo, Braus, Gerhard H

“…The COP9 signalosome complex (CSN) is a crucial regulator of ubiquitin ligases. Defects in CSN result in embryonic impairment and death in higher eukaryotes,…”
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