Search Results - "Schwerdtfeger, Luke A."
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Human colon function ex vivo: Dependence on oxygen and sensitivity to antibiotic
Published in PloS one (16-05-2019)“…Human intestines contain a heterogeneous collection of cells that include immune, neural and epithelial elements interacting in a highly complex physiology…”
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2
Vasoactive intestinal peptide regulates ileal goblet cell production in mice
Published in Physiological reports (01-02-2020)“…Innervation of the intestinal mucosa has gained more attention with demonstrations of tuft and enteroendocrine cell innervation. However, the role(s) these…”
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3
An organotypic slice model for ex vivo study of neural, immune, and microbial interactions of mouse intestine
Published in American journal of physiology: Gastrointestinal and liver physiology (15-02-2016)“…Organotypic tissue slices provide seminatural, three-dimensional microenvironments for use in ex vivo study of specific organs and have advanced investigative…”
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4
Sex differences in anatomic plasticity of gut neuronal–mast cell interactions
Published in Physiological reports (01-10-2021)“…The gut wall houses mast cells that are anatomically situated near enteric neuronal fibers. Roles of specific neuropeptides in modulating function of immune…”
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5
Spirals of science
Published in Science (American Association for the Advancement of Science) (14-12-2018)Get full text
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1H‑NMR Profiling of Short-Chain Fatty Acid Content from a Physiologically Accurate Gut-on-a-Chip Device
Published in Analytical chemistry (Washington) (19-07-2022)“…It has been shown that short-chain fatty acids (SCFAs) produced by the gut microbiome are of importance to host tissue health; however, measuring such…”
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From organotypic culture to body‐on‐a‐chip: A neuroendocrine perspective
Published in Journal of neuroendocrinology (01-03-2019)“…The methods used to study neuroendocrinology have been as diverse as the discoveries to come out of the field. Maintaining live neurones outside of a body in…”
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8
Gamma-delta T cells suppress microbial metabolites that activate striatal neurons and induce repetitive/compulsive behavior in mice
Published in Brain, behavior, and immunity (01-03-2024)“…•γδ T cells regulate the gut microbiota.•In the absence of γδ T cells, mice develop a microbial dysbiosis with the growth of microbes involved in the…”
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High incidence of a third head of biceps brachii in females
Published in Translational research in anatomy (01-09-2018)“…Incidence rates of a third head of biceps brachii muscle have been shown to vary based on race, sex, and side of the body. Traditionally, males were thought to…”
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10
High-salt diet induces microbiome dysregulation, neuroinflammation and anxiety in the chronic period after mild repetitive closed head injury in adolescent mice
Published in Brain communications (2024)“…Abstract The associations between human concussions and subsequent sequelae of chronic neuropsychiatric and cardiovascular diseases such as hypertension have…”
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1 H-NMR Profiling of Short-Chain Fatty Acid Content from a Physiologically Accurate Gut-on-a-Chip Device
Published in Analytical chemistry (Washington) (19-07-2022)Get full text
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12
Maternal immune activation by toll-like receptor 7 agonist during mid-gestation increases susceptibility to blood-brain barrier leakage after puberty
Published in Brain behavior and immunity integrative (01-12-2024)“…Maternal immune activation (MIA), a maternal stressor, increases risk for neuropsychiatric diseases, such as Major Depressive Disorder in offspring. MIA of…”
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Anatomic Plasticity and Functional Impacts of Neural – Immune and Neural – Epithelial Signaling in the Intestine
Published 01-01-2021“…The intestinal wall is a multicompartmental barrier tissue composed of over 25 distinct cell types with integrated and complex signaling both within and…”
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Dissertation