Search Results - "Schweneker, Marc"

Suberoylanilide Hydroxamic Acid Reactivates HIV from Latently Infected Cells by Contreras, Xavier, Schweneker, Marc, Chen, Ching-Shih, McCune, Joseph M., Deeks, Steven G., Martin, Jeffrey, Peterlin, B.Matija

“…Human immunodeficiency virus (HIV) persists in a latent form in infected individuals treated effectively with highly active antiretroviral therapy (HAART). In…”
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Preclinical development of a first-in-class vaccine encoding HER2, Brachyury and CD40L for antibody enhanced tumor eradication by Hinterberger, Maria, Endt, Kathrin, Bathke, Barbara, Habjan, Matthias, Heiseke, Alexander, Schweneker, Marc, Von Rohrscheidt, Julia, Atay, Cigdem, Chaplin, Paul, Kalla, Markus, Hausmann, Jürgen, Schmittwolf, Carolin, Lauterbach, Henning, Volkmann, Ariane, Hochrein, Hubertus, Medina-Echeverz, José

“…The induction of antiviral innate immunity by systemic immunization with live virus can be employed to positively impact the response to therapeutic…”
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Regulation of Raf-Akt Cross-talk by Moelling, Karin, Schad, Karen, Bosse, Magnus, Zimmermann, Sven, Schweneker, Marc

“…We have recently shown that the Ras-Raf-MEK-ERK and phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathways can cross-talk in the human breast cancer cell…”
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The Vaccinia Virus O1 Protein Is Required for Sustained Activation of Extracellular Signal-Regulated Kinase 1/2 and Promotes Viral Virulence by SCHWENEKER, Marc, LUKASSEN, Susanne, SPÄTH, Michaela, WOLFERSTÄTTER, Michael, BABEL, Eveline, BRINKMANN, Kay, WIELERT, Ursula, CHAPLIN, Paul, SUTER, Mark, HAUSMANN, Jürgen

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Immediate-Early Expression of a Recombinant Antigen by Modified Vaccinia Virus Ankara Breaks the Immunodominance of Strong Vector-Specific B8R Antigen in Acute and Memory CD8 T-Cell Responses by Baur, Karen, Brinkmann, Kay, Schweneker, Marc, Pätzold, Juliane, Meisinger-Henschel, Christine, Hermann, Judith, Steigerwald, Robin, Chaplin, Paul, Suter, Mark, Hausmann, Jürgen

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JM4 is a four-transmembrane protein binding to the CCR5 receptor by Schweneker, Marc, Bachmann, André S., Moelling, Karin

“…The CC chemokine receptor 5 (CCR5) is a major co-receptor for human immunodeficiency virus (HIV) and CCR5 mutants lacking the carboxy (C)-terminus interfere…”
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Immunogenicity of propagation-restricted vesicular stomatitis virus encoding Ebola virus glycoprotein in guinea pigs by Locher, Samira, Schweneker, Marc, Hausmann, Jürgen, Zimmer, Gert

“…Vesicular stomatitis virus (VSV) expressing the Ebola virus (EBOV) glycoprotein (GP) in place of the VSV glycoprotein G (VSV/EBOV-GP) is a promising EBOV…”
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Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection by Jones, R Brad, Ndhlovu, Lishomwa C, Barbour, Jason D, Sheth, Prameet M, Jha, Aashish R, Long, Brian R, Wong, Jessica C, Satkunarajah, Malathy, Schweneker, Marc, Chapman, Joan M, Gyenes, Gabor, Vali, Bahareh, Hyrcza, Martin D, Yue, Feng Yun, Kovacs, Colin, Sassi, Aref, Loutfy, Mona, Halpenny, Roberta, Persad, Desmond, Spotts, Gerald, Hecht, Frederick M, Chun, Tae-Wook, McCune, Joseph M, Kaul, Rupert, Rini, James M, Nixon, Douglas F, Ostrowski, Mario A

“…Progressive loss of T cell functionality is a hallmark of chronic infection with human immunodeficiency virus 1 (HIV-1). We have identified a novel population…”
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The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma by Pechloff, Konstanze, Holch, Julian, Ferch, Uta, Schweneker, Marc, Brunner, Kristina, Kremer, Markus, Sparwasser, Tim, Quintanilla-Martinez, Leticia, Zimber-Strobl, Ursula, Streubel, Berthold, Gewies, Andreas, Peschel, Christian, Ruland, Jürgen

“…Peripheral T cell lymphomas (PTCLs) are highly aggressive malignancies with poor prognosis. Their molecular pathogenesis is not well understood and small…”
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Recombinant Modified Vaccinia Virus Ankara Generating Ebola Virus-Like Particles by Schweneker, Marc, Laimbacher, Andrea S, Zimmer, Gert, Wagner, Susanne, Schraner, Elisabeth M, Wolferstätter, Michael, Klingenberg, Marieken, Dirmeier, Ulrike, Steigerwald, Robin, Lauterbach, Henning, Hochrein, Hubertus, Chaplin, Paul, Suter, Mark, Hausmann, Jürgen

“…There are currently no approved therapeutics or vaccines to treat or protect against the severe hemorrhagic fever and death caused by Ebola virus (EBOV). Ebola…”
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The mycobacterial cord factor adjuvant analogue trehalose-6,6′-dibehenate (TDB) activates the Nlrp3 inflammasome by Schweneker, Katrin, Gorka, Oliver, Schweneker, Marc, Poeck, Hendrik, Tschopp, Jürg, Peschel, Christian, Ruland, Jürgen, Groß, Olaf

“…Abstract The success of a vaccine consists in the induction of an innate immune response and subsequent activation of the adaptive immune system. Because…”
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Recombinant modified vaccinia virus Ankara generating excess early double-stranded RNA transiently activates protein kinase R and triggers enhanced innate immune responses by Wolferstätter, Michael, Schweneker, Marc, Späth, Michaela, Lukassen, Susanne, Klingenberg, Marieken, Brinkmann, Kay, Wielert, Ursula, Lauterbach, Henning, Hochrein, Hubertus, Chaplin, Paul, Suter, Mark, Hausmann, Jürgen

“…Double-stranded RNA (dsRNA) is an important molecular pattern associated with viral infection and is detected by various extra- and intracellular recognition…”
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ID: 78 by Wolferstätter, Michael, Schweneker, Marc, Späth, Michaela, Lukassen, Susanne, Klingenberg, Marieken, Brinkmann, Kay, Wielert, Ursula, Lauterbach, Henning, Hochrein, Hubertus, Chaplin, Paul, Suter, Mark, Hausmann, Jürgen

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ID: 78: Recombinant MVA generating excess early double-stranded RNA transiently activates PKR and triggers enhanced innate immune responses by Wolferstätter, Michael, Schweneker, Marc, Späth, Michaela, Lukassen, Susanne, Klingenberg, Marieken, Brinkmann, Kay, Wielert, Ursula, Lauterbach, Henning, Hochrein, Hubertus, Chaplin, Paul, Suter, Mark, Hausmann, Jürgen

“…Poxviruses produce significant amounts of double-stranded (ds)RNA late in infection due to convergent transcription of late genes, but have evolved to avoid…”
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HIV-Induced Changes in T Cell Signaling Pathways by Schweneker, Marc, Favre, David, Martin, Jeffrey N, Deeks, Steven G, McCune, Joseph M

“…Infection with HIV usually results in chronic activation of the immune system, with profound quantitative and qualitative changes in the T cell compartment. To…”
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The mycobacterial cord factor adjuvant analogue trehalose-6,6a2-dibehenate (TDB) activates the Nlrp3 inflammasome by Schweneker, Katrin, Gorka, Oliver, Schweneker, Marc, Poeck, Hendrik, Tschopp, Juerg, Peschel, Christian, Ruland, Juergen, Gross, Olaf

“…The success of a vaccine consists in the induction of an innate immune response and subsequent activation of the adaptive immune system. Because antigens are…”
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WD‐repeat‐propeller‐FYVE protein, ProF, binds VAMP2 and protein kinase Cζ by Fritzius, Thorsten, Frey, Alexander D., Schweneker, Marc, Mayer, Daniel, Moelling, Karin

“…We have recently identified a protein, consisting of seven WD repeats, presumably forming a β‐propeller, and a domain identified in Fab1p, YOTB, VAC1p, and…”
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A WD-FYVE protein binds to the kinases Akt and PKCζ/λ by Fritzius, Thorsten, Burkard, Gabriela, Haas, Elvira, Heinrich, Jochen, Schweneker, Marc, Bosse, Magnus, Zimmermann, Sven, Frey, Alexander D., Caelers, Antje, Bachmann, Andre S., Moelling, Karin

“…WD (tryptophan-aspartic acid dipeptide)-repeat proteins play a central role in signal transduction cascades by co-ordinating the interaction of key signalling…”
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The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma by Pechloff, Konstanze, Holch, Julian, Ferch, Uta, Schweneker, Marc, Brunner, Kristina, Kremer, Markus, Sparwasser, Tim, Quintanilla-Martinez, Leticia, Zimber-Strobl, Ursula, Streubel, Berthold, Gewies, Andreas, Peschel, Christian, Ruland, Jürgen

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HIV-Induced Changes in T Cell Signaling Pathways1 by Schweneker, Marc, Favre, David, Martin, Jeffrey N., Deeks, Steven G., McCune, Joseph M.

“…Infection with HIV usually results in chronic activation of the immune system, with profound quantitative and qualitative changes in the T cell compartment. To…”
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