Search Results - "Schwen, Lars Ole"

Intrahepatic Vascular Anatomy in Rats and Mice--Variations and Surgical Implications by Sänger, Constanze, Schenk, Andrea, Schwen, Lars Ole, Wang, Lei, Gremse, Felix, Zafarnia, Sara, Kiessling, Fabian, Xie, Chichi, Wei, Weiwei, Richter, Beate, Dirsch, Olaf, Dahmen, Uta

“…The intra-hepatic vascular anatomy in rodents, its variations and corresponding supplying and draining territories in respect to the lobar structure of the…”
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Computational Modeling in Liver Surgery by Christ, Bruno, Dahmen, Uta, Herrmann, Karl-Heinz, König, Matthias, Reichenbach, Jürgen R, Ricken, Tim, Schleicher, Jana, Ole Schwen, Lars, Vlaic, Sebastian, Waschinsky, Navina

“…The need for extended liver resection is increasing due to the growing incidence of liver tumors in aging societies. Individualized surgical planning is the…”
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Ten simple rules for typographically appealing scientific texts by Schwen, Lars Ole

“…Introduction Text is ubiquitous in everyday scientific work—when was the last time you spent 5 minutes working without writing, reading, or interacting with…”
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Ten quick tips for getting the most scientific value out of numerical data by Schwen, Lars Ole, Rueschenbaum, Sabrina

“…Most studies in the life sciences and other disciplines involve generating and analyzing numerical data of some type as the foundation for scientific findings…”
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Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage by Schenk, Arne, Ghallab, Ahmed, Hofmann, Ute, Hassan, Reham, Schwarz, Michael, Schuppert, Andreas, Schwen, Lars Ole, Braeuning, Albert, Teutonico, Donato, Hengstler, Jan G., Kuepfer, Lars

“…Diseases and toxins may lead to death of active liver tissue, resulting in a loss of total clearance capacity at the whole-body level. However, it remains…”
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Evaluating generic AutoML tools for computational pathology by Schwen, Lars Ole, Schacherer, Daniela, Geißler, Christian, Homeyer, André

“…Image analysis tasks in computational pathology are commonly solved using convolutional neural networks (CNNs). The selection of a suitable CNN architecture…”
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Editorial: Multiscale modeling for the liver by Ho, Harvey, Rezania, Vahid, Schwen, Lars Ole

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Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism by Albadry, Mohamed, Höpfl, Sebastian, Ehteshamzad, Nadia, König, Matthias, Böttcher, Michael, Neumann, Jasna, Lupp, Amelie, Dirsch, Olaf, Radde, Nicole, Christ, Bruno, Christ, Madlen, Schwen, Lars Ole, Laue, Hendrik, Klopfleisch, Robert, Dahmen, Uta

“…Little is known about the impact of morphological disorders in distinct zones on metabolic zonation. It was described recently that periportal fibrosis did…”
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Representative Sinusoids for Hepatic Four-Scale Pharmacokinetics Simulations by Schwen, Lars Ole, Schenk, Arne, Kreutz, Clemens, Timmer, Jens, Bartolomé Rodríguez, María Matilde, Kuepfer, Lars, Preusser, Tobias

“…The mammalian liver plays a key role for metabolism and detoxification of xenobiotics in the body. The corresponding biochemical processes are typically…”
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Spatio-temporal simulation of first pass drug perfusion in the liver by Schwen, Lars Ole, Krauss, Markus, Niederalt, Christoph, Gremse, Felix, Kiessling, Fabian, Schenk, Andrea, Preusser, Tobias, Kuepfer, Lars

“…The liver is the central organ for detoxification of xenobiotics in the body. In pharmacokinetic modeling, hepatic metabolization capacity is typically…”
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Evaluation of a numerical simulation for cryoablation - comparison with bench data, clinical kidney and lung cases by Rieder, Christian, Schwenke, Michael, Pätz, Torben, Georgii, Joachim, Ballhausen, Hanne, Schwen, Lars Ole, Haase, Sabrina, Preusser, Tobias

“…The accuracy of a numerical simulation of cryoablation ice balls was evaluated in gel phantom data as well as clinical kidney and lung cases. To evaluate the…”
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Artificial Intelligence in Pathology: From Prototype to Product by Homeyer, André, Lotz, Johannes, Schwen, Lars Ole, Weiss, Nick, Romberg, Daniel, Höfener, Henning, Zerbe, Norman, Hufnagl, Peter

“…Modern image analysis techniques based on artificial intelligence (AI) have great potential to improve the quality and efficiency of diagnostic procedures in…”
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Quantification of Hepatic Vascular and Parenchymal Regeneration in Mice by Xie, Chichi, Schwen, Lars Ole, Wei, Weiwei, Schenk, Andrea, Zafarnia, Sara, Gremse, Felix, Dahmen, Uta

“…Liver regeneration consists of cellular proliferation leading to parenchymal and vascular growth. This study complements previous studies on cellular…”
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Data-Driven Discovery of Immune Contexture Biomarkers by Schwen, Lars Ole, Andersson, Emilia, Korski, Konstanty, Weiss, Nick, Haase, Sabrina, Gaire, Fabien, Hahn, Horst K, Homeyer, André, Grimm, Oliver

“…Features characterizing the immune contexture (IC) in the tumor microenvironment can be prognostic and predictive biomarkers. Identifying novel biomarkers can…”
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Analysis and Algorithmic Generation of Hepatic Vascular Systems by Schwen, Lars Ole, Preusser, Tobias

“…A proper geometric model of the vascular systems in the liver is crucial for modeling blood flow, the connection between the organ and the rest of the…”
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Joining forces for pathology diagnostics with AI assistance: The EMPAIA initiative by Zerbe, Norman, Schwen, Lars Ole, Geißler, Christian, Wiesemann, Katja, Bisson, Tom, Boor, Peter, Carvalho, Rita, Franz, Michael, Jansen, Christoph, Kiehl, Tim-Rasmus, Lindequist, Björn, Pohlan, Nora Charlotte, Schmell, Sarah, Strohmenger, Klaus, Zakrzewski, Falk, Plass, Markus, Takla, Michael, Küster, Tobias, Homeyer, André, Hufnagl, Peter

“…Over the past decade, artificial intelligence (AI) methods in pathology have advanced substantially. However, integration into routine clinical practice has…”
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Focused scores enable reliable discrimination of small differences in steatosis by Homeyer, André, Hammad, Seddik, Schwen, Lars Ole, Dahmen, Uta, Höfener, Henning, Gao, Yan, Dooley, Steven, Schenk, Andrea

“…Automated image analysis enables quantitative measurement of steatosis in histological images. However, spatial heterogeneity of steatosis can make…”
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Automated Detection of Portal Fields and Central Veins in Whole-Slide Images of Liver Tissue by Budelmann, Daniel, Laue, Hendrik, Weiss, Nick, Dahmen, Uta, D’Alessandro, Lorenza A., Biermayer, Ina, Klingmüller, Ursula, Ghallab, Ahmed, Hassan, Reham, Begher-Tibbe, Brigitte, Hengstler, Jan G., Schwen, Lars Ole

“…Many physiological processes and pathological phenomena in the liver tissue are spatially heterogeneous. At a local scale, biomarkers can be quantified along…”
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Statistical osteoporosis models using composite finite elements: A parameter study by Wolfram, Uwe, Ole Schwen, Lars, Simon, Ulrich, Rumpf, Martin, Wilke, Hans-Joachim

“…Abstract Osteoporosis is a widely spread disease with severe consequences for patients and high costs for health care systems. The disease is characterised by…”
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Digitization of Pathology Labs: A Review of Lessons Learned by Schwen, Lars Ole, Kiehl, Tim-Rasmus, Carvalho, Rita, Zerbe, Norman, Homeyer, André

“…Pathology laboratories are increasingly using digital workflows. This has the potential of increasing laboratory efficiency, but the digitization process also…”
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