Search Results - "Schwem, Brian"

High rates of tenofovir failure in a CRF01_AE-predominant HIV epidemic in the Philippines by Salvana, Edsel Maurice T., Samonte, Genesis May J., Telan, Elizabeth, Leyritana, Katerina, Tactacan-Abrenica, Rosario Jessica, Ching, Patrick R., Arevalo, Geraldine M., Dungca, Niña Theresa, Peñalosa-Ramos, Christine, Mendoza, Kevin Anthony R., Trinidad, Lyka F., Tonga, Angelo dela, Lim, Jodor, Destura, Raul, Alejandria, Marissa, Solante, Rontgene, Arcangel, Lalaine, Palaypayon, Noel S., Schwem, Brian E.

“…• Our study is the first systematic acquired drug resistance surveillance of HIV patients from the Philippines, which currently has one of the fastest growing…”
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HIV‐1 Subtype Shift in the Philippines is Associated With High Transmitted Drug Resistance, High Viral Loads, and Fast Immunologic Decline by Salvaña, Edsel Maurice T., Dungca, Niña Theresa, Arevalo, Geraldine, Li, Kingbherly, Francisco, Christian, Penalosa, Christine, dela Tonga, Angelo, Leyritana, Katerina, Solante, Rontgene, Tactacan-Abrenica, Rosario Jessica, Lim, Jodor, Alejandria, Marissa, Palaypayon, Noel, Schwem, Brian

“…•Transmitted drug resistance in the Philippines is high.•CRF01_AE is associated with higher viral load and lower CD4.•Drug-resistance testing is recommended in…”
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Assessment of a multiplex PCR and Nanopore-based method for dengue virus sequencing in Indonesia by Stubbs, Samuel C B, Blacklaws, Barbara A, Yohan, Benediktus, Yudhaputri, Frilasita A, Hayati, Rahma F, Schwem, Brian, Salvaña, Edsel M, Destura, Raul V, Lester, James S, Myint, Khin S, Sasmono, R Tedjo, Frost, Simon D W

“…Dengue virus (DENV) infects hundreds of thousands of people annually in Indonesia. However, DENV sequence data from the country are limited, as samples from…”
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The changing molecular epidemiology of HIV in the Philippines by Salvaña, Edsel Maurice T, Schwem, Brian E, Ching, Patrick, Frost, Simon D.W, Ganchua, Sharie Keanne G, Itable, Jill

“…Highlights • The molecular epidemiology of HIV in the Philippines has changed substantially. • There is a unique opportunity for comparing outcomes and subtype…”
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Cross-linking between Helices within Subunit a of Escherichia coli ATP Synthase Defines the Transmembrane Packing of a Four-helix Bundle by Schwem, Brian E., Fillingame, Robert H.

“…Subunit a of F1F0 ATP synthase is required in the H+ transport driven rotation of the c-ring of F0, the rotation of which is coupled to ATP synthesis in F1…”
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The Cytoplasmic Loops of Subunit a of Escherichia coli ATP Synthase May Participate in the Proton Translocating Mechanism by Moore, Kyle J., Angevine, Christine M., Vincent, Owen D., Schwem, Brian E., Fillingame, Robert H.

“…Subunit a plays a key role in promoting H+ transport and the coupled rotary motion of the subunit c ring in F1F0-ATP synthase. H+ binding and release occur at…”
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HIV Treatment Failure and Acquired Drug Resistance After 1 Year on Antiretrovirals in the Philippines by Salvana, Edsel Maurice, Schwem, Brian, Samonte, Genesis, Tactacan-Abrenica, Rosario, Telan, Elizabeth, Mendoza, Kevin, Arevalo, Geraldine, Alejandria, Marissa, Leyritana, Katerina, Trinidad, Lyka, Lim, Jodor

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Fluidity of Structure and Swiveling of Helices in the Subunit c Ring of Escherichia coli ATP Synthase as Revealed by Cysteine-Cysteine Cross-Linking by Vincent, Owen D., Schwem, Brian E., Steed, P. Ryan, Jiang, Warren, Fillingame, Robert H.

“…Subunit c in the membrane-traversing F0 sector of Escherichia coli ATP synthase is known to fold with two transmembrane helices and form an oligomeric ring of…”
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The Tricarballylate Utilization (tcuRABC) Genes of Salmonella enterica Serovar Typhimurium LT2 by Lewis, Jeffrey A, Horswill, Alexander R, Schwem, Brian E, Escalante-Semerena, Jorge C

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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1902. Whole Genome Sequence analysis of early community transmission SARS-CoV-2 samples in the Philippines by Arevalo, Geraldine, Dungca, Nina Theresa, Salvana, Edsel Maurice, Schwem, Brian

“…Abstract Background The Philippines has recorded nearly 3.7 million COVID-19 cases and more than 60,000 deaths. The first three cases of COVID-19 in the…”
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633. Nanopore Sequencing and In-house Bioinformatic Pipeline for Rapid and Accurate Detection of NRTI, NNRTI, PI, and INSTI Drug Resistance Mutations by Salvaña, Edsel Maurice, Arevalo, Geraldine M, Dungca, Niña Theresa, Alpay, Riacarl, Schwem, Brian

“…Abstract Background Sanger-based sequencing (SBS) remains the gold standard for HIV-1 drug resistance testing (DRT). However, SBS output is still limited to an…”
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1257. Antiretroviral treatment failure in a prospective cohort of Persons Living with HIV in the Philippines by Dungca, Nina Theresa, Schwem, Brian, Arevalo, Geraldine, Li, Kingbherly L, Salvana, Edsel Maurice

“…Abstract Background Widespread access to antiretrovirals has resulted in improved survival among PLHIV in resource-limited settings. In a previous study, ART…”
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Genotypic persistence of dengue virus in the Philippines by Galarion, Ma. Jowina, Schwem, Brian, Pangilinan, Coleen, dela Tonga, Angelo, Petronio-Santos, Joy Ann, delos Reyes, Erlinda, Destura, Raul

“…The Philippines is known to have one of the world's highest prevalences of dengue infection. The disease has been endemic in the country since 1956 and the…”
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361. Residual Lamivudine-Resistant Hepatitis B Virus Detected on Next-Generation Sequencing of Treatment-Experienced HIV Patients Failing Antiretrovirals by Schwem, Brian, Francisco, Christian, Dungca, Nina Theresa, Arevalo, Geraldine, Penalosa-Ramos, Christine, Lim, Jodor, Salvana, Edsel Maurice T

“…Abstract Background Hepatitis B is highly prevalent in the Philippines, with 17% of the population infected. With the fastest-growing HIV epidemic in the…”
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1282. Detection of HIV Transmitted Drug Resistance by Next-Generation Sequencing in a CRF01_AE Predominant Epidemic by Salvana, Edsel Maurice, Dungca, Nina, Arevalo, Geraldine, Leyritana, Katerina, Francisco, Christian, Penalosa, Christine, Destura, Raul, Lim, Jodor, Schwem, Brian

“…Abstract Background The Philippines has the fastest growing HIV epidemic in the Asia-Pacific. Concurrent with this is a subtype shift from B to CRF01_AE. We…”
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1281. Emergence of a B/F1 HIV Recombinant in the Philippines: A Potentially New Circulating Recombinant Form by Schwem, Brian, Dungca, Nina, Arevalo, Geraldine, Francisco, Christian, Penalosa, Christine, Leyritana, Katerina, Destura, Raul, Lim, Jodor, Tactacan-Abrenica, Rosario, Telan, Elizabeth, Solante, Rongene, Salvana, Edsel Maurice

“…Abstract Background The Philippines has one of the fastest growing HIV epidemics globally. This was accompanied by a switch from subtype B to CRF01_AE. With a…”
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2507. Transmitted and Acquired NNRTI Resistance in the Philippines: Are Newer Generation NNRTIs a Viable Option? by Theresa Dungca, Nina, Schwem, Brian, Arevalo, Geraldine, Francisco, Christian, Penalosa-Ramos, Christine, Ching, Patrick, Leyritana, Katerina, Destura, Raul, Lim, Jodor, Tactacan-Abrenica, Rosario, Telan, Elizabeth, Solante, Rontgene, Samonte, Genesis, Trinidad, Lyka, Mendoza, Kevin, Alejandria, Marissa M, Salvana, Edsel Maurice T

“…Abstract Background Doravirine, rilpivirine, and etravirine are newer generation non-nucleoside reverse transcriptase inhibitors (NNRTI) that are intended to…”
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HIV Transmitted Drug Resistance in the Philippines: The Case for Baseline Genotyping and Drug Resistance Testing by Salvana, Edsel Maurice, Schwem, Brian, Penalosa, Christine, Arevalo, Geraldine, Dungca, Nina, Lim, Jodor, Leyritana, Katerina, Destura, Raul

“…Abstract Background The Philippines has one of the fastest growing HIV epidemics in the world. Parallel to the increase is a shift in HIV subtype from B to…”
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High Tenofovir Failure Rates in an Emerging, Non-B Subtype HIV Epidemic by Salvana, Edsel Maurice, Schwem, Brian, Samonte, Genesis, Telan, Elizabeth, Tactacan-Abrenica, Rosario, Ching, Patrick, Mendoza, Kevin, Arevalo, Geraldine, Alejandria, Marissa, Leyritana, Katerina, Trinidad, Lyka, Penalosa, Christine, Lim, Jodor

“…Abstract Background The WHO-recommended regimen for antiretrovirals (ARVs) is tenofovir (TDF) + lamivudine/emtricitabine (3TC/FTC) + efavirenz (EFV), based on…”
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1541The Changing Molecular Epidemiology of HIV in the Philippines: Major Shift from Subtype B to CRF01_AE by Schwem, Brian, Itable, Jill, Ching, Patrick, Ganchua, Sharie, Alejandria, Marissa, Lim, Jodor, Destura, Raul, Salvana, Edsel Maurice

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