Search Results - "Schweizer, U"

Selenium and selenoproteins in mammals: extraordinary, essential, enigmatic by Schomburg, L, Schweizer, U, Köhrle, J

“…Selenium (Se), once known only for its potential toxicity, is now well established as an essential trace element for mammals. Insufficient Se intake…”
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Neuronal and ependymal expression of selenoprotein P in the human brain by Scharpf, M, Schweizer, U, Arzberger, T, Roggendorf, W, Schomburg, L, Köhrle, J

“…Selenoprotein P (SePP) is central to selenium (Se) metabolism in the mammalian organism. Human SePP contains 10 Se atoms that are covalent constituents of the…”
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Contrasting roles of dietary selenium and selenoproteins in chemically induced hepatocarcinogenesis by Kasaikina, Marina V, Turanov, Anton A, Avanesov, Andrei, Schweizer, Ulrich, Seeher, Sandra, Bronson, Roderick T, Novoselov, Sergey N, Carlson, Bradley A, Hatfield, Dolph L, Gladyshev, Vadim N

“…Selenium (Se) has long been known for its cancer prevention properties, but the molecular basis remains unclear. The principal questions in assessing the…”
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Selenium and selenoproteins in mammals: extraordinary, essential, enigmatic by Schomburg, L., Schweizer, U., K hrle, J.

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Learning of flexible endoscopy, particularly endoscopic vacuum therapy (EVT) by Grund, K. E., Schweizer, U., Zipfel, A., Duckworth-Mothes, B.

“…Background Anastomotic insufficiency and perforations in the gastrointestinal tract are severe complications associated with a high complication rate and…”
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Neuronal and ependymal expression of selenoprotein P in the human brain by Scharpf, M., Schweizer, U., Arzberger, T., Roggendorf, W., Schomburg, L., Köhrle, J.

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Photocrosslinking locates a binding site for the large subunit of human replication protein A to the damaged strand of cisplatin-modified DNA by Schweizer, Ulrich, Hey, Thomas, Lipps, Georg, Krauss, Gerhard

“…The repair proteins XPA, XPC and replication protein A (RPA) have been implicated in the primary recognition of damaged DNA sites during nucleotide excision…”
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Learning of flexible endoscopy, particularly endoscopic vacuum therapy (EVT) by Grund, K E, Schweizer, U, Zipfel, A, Mothes, B

“…Anastomotic insufficiency and perforations in the gastrointestinal tract are severe complications associated with a high complication rate and mortality…”
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Treatment of nonvariceal upper gastrointestinal bleeding: endoluminal-endovascular-surgical by Schweizer, U, Grund, K E, Fundel, J, Wichmann, D, Königsrainer, A

“…Nonvariceal upper gastrointestinal bleeding (UGIB) has a high mortality. Hematemesis sometimes with melena are the leading clinical symptoms. Peptic ulcers and…”
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Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis by Ingold, Irina, Berndt, Carsten, Schmitt, Sabine, Doll, Sebastian, Poschmann, Gereon, Buday, Katalin, Roveri, Antonella, Peng, Xiaoxiao, Porto Freitas, Florencio, Seibt, Tobias, Mehr, Lisa, Aichler, Michaela, Walch, Axel, Lamp, Daniel, Jastroch, Martin, Miyamoto, Sayuri, Wurst, Wolfgang, Ursini, Fulvio, Arnér, Elias S.J., Fradejas-Villar, Noelia, Schweizer, Ulrich, Zischka, Hans, Friedmann Angeli, José Pedro, Conrad, Marcus

“…Selenoproteins are rare proteins among all kingdoms of life containing the 21st amino acid, selenocysteine. Selenocysteine resembles cysteine, differing only…”
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7494 Glycerol Phenylbutyrate Treatment of Two Patients with Monocarboxylate Transporter 8 Deficiency by Zung, A, Sonntag, N, Schweizer, U, Banne, E, Braun, D

“…Disclosure: A. Zung: None. N. Sonntag: None. U. Schweizer: None. E. Banne: None. D. Braun: None. Context: Monocarboxylate transporter 8 (MCT8) deficiency is a…”
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Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death by Seiler, Alexander, Schneider, Manuela, Förster, Heidi, Roth, Stephan, Wirth, Eva K., Culmsee, Carsten, Plesnila, Nikolaus, Kremmer, Elisabeth, Rådmark, Olof, Wurst, Wolfgang, Bornkamm, Georg W., Schweizer, Ulrich, Conrad, Marcus

“…Oxidative stress in conjunction with glutathione depletion has been linked with various acute and chronic degenerative disorders, yet the molecular mechanisms…”
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ENDOCRINE SIDE-EFFECTS OF ANTI-CANCER DRUGS: Thyroid effects of tyrosine kinase inhibitors by Illouz, Frédéric, Braun, Doreen, Briet, Claire, Schweizer, Ulrich, Rodien, Patrice

“…Tyrosine kinase inhibitors (TKIs) are currently used by most oncologists. Among their side effects, thyroid dysfunctions are nowadays clearly observed. Whereas…”
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Biosynthesis of 3-Iodothyronamine From T4 in Murine Intestinal Tissue by Hoefig, Carolin S, Wuensch, Tilo, Rijntjes, Eddy, Lehmphul, Ina, Daniel, Hannelore, Schweizer, Ulrich, Mittag, Jens, Köhrle, Josef

“…The endogenous metabolite 3-iodothyronamine (3-T1AM) induces strong hypothermia and bradycardia at pharmacological doses. Although its biosynthesis from…”
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Breach Remedies, Performance Excuses, and Investment Incentives by Schweizer, Urs

“…The present article investigates investment decisions generated by legal regimes that combine different breach remedies and performance excuses from contract…”
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Missense mutation in selenocysteine synthase causes cardio-respiratory failure and perinatal death in mice which can be compensated by selenium-independent GPX4 by Fradejas-Villar, Noelia, Zhao, Wenchao, Reuter, Uschi, Doengi, Michael, Ingold, Irina, Bohleber, Simon, Conrad, Marcus, Schweizer, Ulrich

“…Selenoproteins are a small family of proteins containing the trace element selenium in form of the rare amino acid selenocysteine (Sec), which is decoded by…”
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Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues by Schomburg, Lutz, Schweizer, Ulrich, Holtmann, Bettina, Flohé, Leopold, Sendtner, Michael, Köhrle, Josef

“…Selenoprotein P (SePP), the major selenoprotein in plasma, has been implicated in selenium transport, selenium detoxification or antioxidant defence. We…”
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Peroxides and peroxide-degrading enzymes in the thyroid by Schweizer, Ulrich, Chiu, Jazmin, Köhrle, Josef

“…Iodination of thyroglobulin is the key step of thyroid hormone biosynthesis. It is catalyzed by thyroid peroxidase and occurs within the follicular space at…”
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Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy by Kudin, Alexei P., Baron, Gregor, Zsurka, Gábor, Hampel, Kevin G., Elger, Christian E., Grote, Alexander, Weber, Yvonne, Lerche, Holger, Thiele, Holger, Nürnberg, Peter, Schulz, Herbert, Ruppert, Ann-Kathrin, Sander, Thomas, Cheng, Qing, Arnér, Elias SJ, Schomburg, Lutz, Seeher, Sandra, Fradejas-Villar, Noelia, Schweizer, Ulrich, Kunz, Wolfram S.

“…Increased oxidative stress has been widely implicated in the pathogenesis in various forms of human epilepsy. Here, we report a homozygous mutation in TXNRD1…”
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High-Resolution Ribosome Profiling Reveals Gene-Specific Details of UGA Re-Coding in Selenoprotein Biosynthesis by Bohleber, Simon, Fradejas-Villar, Noelia, Zhao, Wenchao, Reuter, Uschi, Schweizer, Ulrich

“…Co-translational incorporation of selenocysteine (Sec) into selenoproteins occurs at UGA codons in a process in which translational elongation competes with…”
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