Search Results - "Schweizer, Júnia"
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1
Cardiac MRI in acromegaly: looking for a big heart
Published in Pituitary (01-08-2024)Get full text
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2
Soluble Alpha Klotho in Acromegaly: Comparison With Traditional Markers of Disease Activity
Published in The journal of clinical endocrinology and metabolism (01-08-2021)“…Abstract Context Soluble alpha klotho (sαKL) has been linked to growth hormone (GH) action, but systematic evaluation and comparisons with traditional…”
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3
Prevalence and Outcome of Secondary Hypogonadism in Male Patients with Cushing's Syndrome and Mild Autonomous Cortisol Secretion
Published in European journal of endocrinology (05-08-2024)“…Secondary hypogonadism (SH) is common in men with Cushing's syndrome (CS), but its impact on comorbidities is largely unknown and longitudinal data are scarce…”
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4
Angiotensin-converting enzyme inhibition increases glucose-induced insulin secretion in response to acute restraint
Published in Clinical and experimental pharmacology & physiology (01-12-2012)“…Summary There is increasing evidence suggesting involvement of the renin–angiotensin system (RAS) in carbohydrate metabolism and its response to stress. Thus,…”
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5
Activated AMP-protein kinase (pAMPK) is overexpressed in human somatotroph pituitary adenomas
Published in Molecular and cellular endocrinology (01-10-2024)“…AMPK (AMP-activated protein kinase) is an enzyme that acts as a metabolic sensor and regulates multiple pathways via phosphorylating proteins in metabolic and…”
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Pasireotide treatment does not modify hyperglycemic and corticosterone acute restraint stress responses in rats
Published in Stress (Amsterdam, Netherlands) (04-07-2018)“…Pasireotide is a new-generation somatostatin analog that acts through binding to multiple somatostatin receptor subtypes. Studies have shown that pasireotide…”
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7
Long-Term Remission of Acromegaly after Octreotide Withdrawal Is an Uncommon and Frequently Unsustainable Event
Published in Neuroendocrinology (01-01-2017)“…Long-term remission of acromegaly after somatostatin analog withdrawal has been reported in 18-42% of patients in studies with a relatively small number of…”
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Reduced protein expression of the phosphodiesterases PDE4A4 and PDE4A8 in AIP mutation positive somatotroph adenomas
Published in Molecular and cellular endocrinology (15-11-2018)“…Type 4 phosphodiesterases (PDE4s) of the large PDE enzyme superfamily have unique specificity for cAMP and may, therefore, be relevant for somatotroph…”
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8008 Insulin-like Growth Factor-1 (IGF-1) Level Fluctuations and Patient Reported Outcomes (PROMS) During Treatment with Long-acting Somatostatin Receptor Ligands (SRLs) for Acromegaly: a Prospective Study
Published in Journal of the Endocrine Society (05-10-2024)“…Abstract Disclosure: I. Remba-Shapiro: None. J.R. Schweizer: None. K.J. Liebert: Consulting Fee; Self; Crinetics, Recordati Rare Diseases, Novo Nordisk. K…”
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10
THU056 Reference Interval For Serum Soluble Alpha Klotho, A Sensitive Biomarker Of Growth Hormone (GH) Excess
Published in Journal of the Endocrine Society (05-10-2023)“…Abstract Disclosure: J.R. Schweizer: None. K. Schilbach: None. M. Haenelt: None. A.P. Gagliardo: None. A. Peters: None. B. Thorand: None. S. Störmann: None. J…”
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PREVALENCE AND OUTCOME OF PRIMARY ALDOSTERONISM IN PBMAH: A SINGLE CENTER STUDY AND A SYSTEMATIC REVIEW OF THE LITERATURE
Published in Journal of hypertension (01-05-2024)“…Objective: Primary bilateral macronodular adrenocortical hyperplasia (PBMAH), characterized by benign adrenocortical macronodules and variable levels of…”
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Growth hormone: isoforms, clinical aspects and assays interference
Published in Clinical diabetes and endocrinology (28-08-2018)“…The measurement of circulating concentrations of growth hormone (GH) is an indispensable tool in the diagnosis of both GH deficiency and GH excess. GH is a…”
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13
SUN-LB62 Differential Regulation of 22 kDa and 20 kDa Growth Hormone Isoforms in Response to Acute Glucose Load and Moderate Intensity Exercise
Published in Journal of the Endocrine Society (08-05-2020)“…Abstract Background: Among growth hormone (GH) isoforms, the 22kDa (22kD) is the most abundant (~90%), followed by 20 kDa GH ((20kD) ~10%). 22kD has known…”
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SUN-LB61 Differential and Opposite Regulation of Acid Labile Subunit (ALS) Versus Insulin-Like Growth Factor I (IGF-I) by Oral Estrogens in Premenopausal Women
Published in Journal of the Endocrine Society (08-05-2020)“…Abstract Background: The impact of estrogens (E2) on the growth hormone (GH)/IGF-I axis is known to depend on route of administration: While oral E2 increases…”
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OR32-2 Alpha Klotho as a Marker of Disease Activity in Acromegaly
Published in Journal of the Endocrine Society (30-04-2019)“…Introduction: Measurements of GH and IGF-I are considered gold standard for biochemical acromegaly diagnosis and follow-up, but have limitations. Novel…”
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MON-327 Soluble Alpha Klotho and IGF-I Before Surgery as Prognostic Factors to Acromegaly Long-term Remission
Published in Journal of the Endocrine Society (08-05-2020)“…Abstract BACKGROUND: Transsphenoidal surgery is the cornerstone of acromegaly treatment. However, cure is obtained in only ~50% of the cases. Until today, no…”
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