Search Results - "Schwarzer, A"

Structural mechanism of GTPase-powered ribosome-tRNA movement by Petrychenko, Valentyn, Peng, Bee-Zen, de A. P. Schwarzer, Ana C., Peske, Frank, Rodnina, Marina V., Fischer, Niels

“…GTPases are regulators of cell signaling acting as molecular switches. The translational GTPase EF-G stands out, as it uses GTP hydrolysis to generate force…”
Get full text

Clinical use of botulinum toxin type A in pain medicine by Schwarzer, A, Mäcken, T, Enax-Krumova, E K

“…Botulinum toxin has been used for decades in the treatment of a variety of painful diseases. Botulinum toxin not only blocks neuromuscular transmission, but…”
Get full text

Repeated exclusive enteral nutrition in the treatment of paediatric Crohn's disease: predictors of efficacy and outcome by Frivolt, K., Schwerd, T., Werkstetter, K. J., Schwarzer, A., Schatz, S. B., Bufler, P., Koletzko, S.

“…Summary Background Exclusive enteral nutrition (EEN) induces remission and mucosal healing in children with active Crohn's disease (CD). Aim To compare short‐…”
Get full text

Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells by Kustikova, O S, Schwarzer, A, Stahlhut, M, Brugman, M H, Neumann, T, Yang, M, Li, Z, Schambach, A, Heinz, N, Gerdes, S, Roeder, I, Ha, T C, Steinemann, D, Schlegelberger, B, Baum, C

“…The transcription factor Evi1 has an outstanding role in the formation and transformation of hematopoietic cells. Its activation by chromosomal rearrangement…”
Get full text

Enantiomer-specific and paracrine leukemogenicity of mutant IDH metabolite 2-hydroxyglutarate by Chaturvedi, A, Araujo Cruz, M M, Jyotsana, N, Sharma, A, Goparaju, R, Schwarzer, A, Görlich, K, Schottmann, R, Struys, E A, Jansen, E E, Rohde, C, Müller-Tidow, C, Geffers, R, Göhring, G, Ganser, A, Thol, F, Heuser, M

“…Canonical mutations in IDH1 and IDH2 produce high levels of the R -enantiomer of 2-hydroxyglutarate ( R -2HG), which is a competitive inhibitor of…”
Get full text

BTM 3566, a Novel Activator of the Mitochondrial Stress Response Induces Robust Therapeutic Responses in Diffuse Large B‐cell Lymphoma in vitro and in vivo by Bashir, Z., Schwarzer, A., Oliveria, M., Kleppa, M., Anantha, A., Kostura, M., Stocum, M., Hembrough, T.

Get full text

Opioid intake prior to admission is not increased in elderly patients with low‐energy fractures: A case–control study in a German hospital population by Schwarzer, A., Kaisler, M., Kipping, K., Seybold, D., Rausch, V., Maier, C., Vollert, J.

“…Background Recent studies revealed an increased prescription rate of opioids for elderly patients suffering bone fractures. To gain further insight, we…”
Get full text

A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients by Beck, D, Thoms, J A I, Palu, C, Herold, T, Shah, A, Olivier, J, Boelen, L, Huang, Y, Chacon, D, Brown, A, Babic, M, Hahn, C, Perugini, M, Zhou, X, Huntly, B J, Schwarzer, A, Klusmann, J-H, Berdel, W E, Wörmann, B, Büchner, T, Hiddemann, W, Bohlander, S K, To, L B, Scott, H S, Lewis, I D, D'Andrea, R J, Wong, J W H, Pimanda, J E

“…Prognostic gene expression signatures have been proposed as clinical tools to clarify therapeutic options in acute myeloid leukemia (AML). However, these…”
Get full text

Evaluation of welfare parameters in laying hens on the basis of a Bavarian survey by Louton, H., Bergmann, S.M., Rauch, E., Liebers, C., Reese, S., Erhard, M.H., Hoeborn, C., Schwarzer, A.

“…Health issues like infestation with poultry red mite (Dermanyssus gallinae) and behavioral problems such as feather pecking and cannibalism are reported as…”
Get full text

Histologically validated scoring system for the assessment of hock burn in broilers by Louton, H., Piller, A., Bergmann, S., Erhard, M., Stracke, J., Spindler, B., Kemper, N., Schmidt, P., Schade, B., Boehm, B., Kappe, E., Bachmeier, J., Schwarzer, A.

“…The assessment of bird-based welfare indicators plays an important role in the evaluation of bird welfare. The aim of the study was to histologically validate…”
Get full text

Development of a prognostic tool for the occurrence of feather pecking and cannibalism in laying hens by Kaesberg, A-K U, Louton, H, Erhard, M, Schmidt, P, Zepp, M, Helmer, F, Schwarzer, A

“…Abstract In July 2015, a German voluntary decree stipulated that the keeping of beak-trimmed laying hens after the 1st of January 2017 will no longer be…”
Get full text

P401: NEXT‐GENERATION FLOW CYTOMETRY TO DETECT MEASURABLE RESIDUAL DISEASE IN ACUTE MYELOID LEUKEMIA USING A 19‐COLOR FULL SPECTRUM FLOW CYTOMETRY PANEL by Fokken, H., Kattre, N., Kloos, A., Heuser, M., Kacprowski, T., Tobias, M., Schwarzer, A.

Get full text

Hyperactivation of mTORC1 and mTORC2 by multiple oncogenic events causes addiction to eIF4E-dependent mRNA translation in T-cell leukemia by Schwarzer, A, Holtmann, H, Brugman, M, Meyer, J, Schauerte, C, Zuber, J, Steinemann, D, Schlegelberger, B, Li, Z, Baum, C

“…High activation of the PI3K–AKT–mTOR pathway is characteristic for T-cell acute lymphoblastic leukemia (T-ALL). The activity of the master regulator of this…”
Get full text

STEM CELL MOBILIZATION AND AUTOLOGOUS STEM CELL TRANSPLANTATION AFTER BENDAMUSTINE, PREDNISONE AND BORTEZOMIB INDUCTION IN MULTIPLE MYELOMA PATIENTS WITH RENAL IMPAIRMENT by Fricke, S., Wang, S., Holzhey, T., Holzvogt, M., Andrea, M., Vucinic, V., Franke, G., Heyn, S., Hell, S., Schetschorke, B., Jentzsch, M., Schwind, S., Zehrfeld, T., Braunert, L., Edelmann, T., Becker, C., Hoffmann, F., Reifenrath, K., Schwarz, M., Schwarzer, A., Flade, F., Hammerschmidt, D., Scholz, M., Merz, M., Platzbecker, U., Pönisch, W.

Get full text

Constitutive IRF8 expression inhibits AML by activation of repressed immune response signaling by Sharma, A, Yun, H, Jyotsana, N, Chaturvedi, A, Schwarzer, A, Yung, E, Lai, C K, Kuchenbauer, F, Argiropoulos, B, Görlich, K, Ganser, A, Humphries, R K, Heuser, M

“…Myeloid differentiation is blocked in acute myeloid leukemia (AML), but the molecular mechanisms are not well characterized. Meningioma 1 (MN1) is…”
Get full text

Samuelson and Solow on the Phillips Curve and the “Menu of Choice”: A Retrospective by Schwarzer, Johannes A

“…This paper focuses on the seminal contribution to the Phillips curve discussion by Samuelson and Solow in 1960, which is usually considered as the first…”
Get full text

Retrospectives: Cost-Push and Demand-Pull Inflation: Milton Friedman and the "Cruel Dilemma" by Schwarzer, Johannes A.

“…This paper addresses two conflicting views in the 1950s and 1960s about the inflation-unemployment tradeoff as given by the Phillips curve. Many economists at…”
Get full text

P1291: BTM‐3566, A NOVEL ACTIVATOR OF THE MITOCHONDRIAL STRESS RESPONSE ERADICATES DIFFUSE LARGE B‐CELL LYMPHOMA IN MICE by Schwarzer, A., Oliveira, M., Kleppa, M.‐J., Anantha, A., Cooper, A., Hembrough, T., Levine, J., Luther, M., Stocum, M., Hannink, M., Liesa‐Roig, M., Kostura, M.

Get full text

P1456: EARLY SAFETY AND CLINICAL COURSE OF PATIENTS WITH ACUTE MYELOID LEUKEMIA AND MEASURABLE RESIDUAL DISEASE RECEIVING GTA002, AN OFF‐THE‐SHELF, EX VIVO‐CULTURED ALLOGENEIC NK CELL PREPARATION by Heuser, M., Fiedler, W., Block, A., Leeuw, D. C., Loosdrecht, A., Astrid Tschan‐Plessl, A., Passweg, J., Kloos, A., Schwarzer, A., Venturini, L., Duru, A. D., Pinkernell, K., Ganser, A.

Get full text

The false-positive rate of uncontrolled diagnostic blocks of the lumbar zygapophysial joints by Schwarzer, A C, Aprill, C N, Derby, R, Fortin, J, Kine, G, Bogduk, N

“…One hundred and seventy-six consecutive patients with chronic low back pain and no history of previous lumbar surgery were studied to determine the…”
Get more information