Search Results - "Schwarzbich, Mark‐Alexander"

Pre-Transplant Serum Leptin Levels and Relapse of Acute Myeloid Leukemia after Allogeneic Transplantation by Schwarzbich, Mark-Alexander, Dai, Hao, Kordelas, Lambros, Beelen, Dietrich W, Radujkovic, Aleksandar, Müller-Tidow, Carsten, Dreger, Peter, Luft, Thomas

“…Weight loss and metabolic activity influence outcome after allogeneic stem cell transplantation (alloSCT). This study evaluates pre-conditioning Leptin, a…”
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Outcome after high‐dose chemotherapy and autologous stem cell transplantation in patients with aggressive B‐cell non‐Hodgkin's lymphoma by Kriegsmann, Katharina, Rieger, Michael, Schwarzbich, Mark‐Alexander, Sitter, Sören, Kriegsmann, Mark, Bruckner, Thomas, Hensel, Manfred, Ho, Anthony Dick, Witzens‐Harig, Mathias, Wuchter, Patrick

“…Objective For more than two decades, high‐dose chemotherapy (HDT) and autologous blood stem cell transplantation (ABSCT) were treatment options for patients…”
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The immune inhibitory receptor osteoactivin is upregulated in monocyte-derived dendritic cells by BCR–ABL tyrosine kinase inhibitors by Schwarzbich, Mark-Alexander, Gutknecht, Michael, Salih, Julia, Salih, Helmut R., Brossart, Peter, Rittig, Susanne M., Grünebach, Frank

“…Multiple approaches presently aim to combine targeted therapies using tyrosine kinase inhibitors with immunotherapy. Ex vivo-generated dendritic cells are…”
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CXCL9 Predicts Severity at the Onset of Chronic Graft-versus-host Disease by Giesen, Nicola, Schwarzbich, Mark-Alexander, Dischinger, Katharina, Becker, Natalia, Hummel, Manuela, Benner, Axel, Radujkovic, Aleksandar, Müller-Tidow, Carsten, Dreger, Peter, Luft, Thomas

“…BACKGROUND.Chronic graft-versus-host disease (cGVHD) represents a double-edged sword. In its nonsevere form, cGVHD associates with better control of the…”
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Ibrutinib by Charalambous, Andriani, Schwarzbich, Mark-Alexander, Witzens-Harig, Mathias

“…Abnormal B-cell receptor (BCR) signalling is a key mechanism of disease progression in B-cell malignancy. Bruton's tyrosine kinase (BTK) has a pivotal role in…”
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Cellular Immunotherapy in B-Cell Malignancy by Schwarzbich, Mark-Alexander, Witzens-Harig, Mathias

“…In recent years, cellular immunotherapy in B-cell malignancies has been driven by adoptive transfer of genetically engineered T cells expressing chimeric…”
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Analysis of clinical characteristics and outcome of patients with previously untreated diffuse large B-cell lymphoma and renal involvement in the rituximab era by Lehners, Nicola, Krämer, Isabelle, Schwarzbich, Mark-Alexander, Ho, Anthony D., Witzens-Harig, Mathias

“…Renal involvement in patients with lymphoma is rare but associated with poor prognosis. We analyzed characteristics and outcome of 22 patients with newly…”
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In Burkitt lymphoma patients who relapse after induction with a short-intensive chemoimmunotherapy protocol, aggressive salvage chemotherapy therapy is ineffective: a single-center retrospective study by Cremer, Martin, Schwarzbich, Mark-Alexander, Schöning, Tilman, Lisenko, Katharina, Ho, Anthony D., Witzens-Harig, Mathias

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Allogeneic Transplantation for Chronic Lymphocytic Leukemia in the Age of Novel Treatment Strategies by Schwarzbich, Mark-Alexander, McClanahan, Fabienne, Gribben, John

“…Hematopoietic stem cell transplantation (HSCT) is the only established potentially curative treatment option for chronic lymphocytic leukemia (CLL) to date…”
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Efficacy and toxicity of a rituximab and methotrexate based regimen (GMALL B-ALL/NHL 2002 protocol) in high risk diffuse large cell B-cell lymphoma patients as a first line treatment by Schwarzbich, Mark-Alexander, Schöning, Tilman, Cremer, Martin, Lisenko, Katharina, Ho, Anthony D., Witzens-Harig, Matthias

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Ibrutinib by Schwarzbich, Mark-Alexander, Witzens-Harig, Matthias

“…Abnormal B-cell receptor (BCR) signaling is a key mechanism of disease progression in B-cell malignancy. Bruton's tyrosine kinase (BTK) has a pivotal role in…”
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Efficient Stem Cell Collection after Modified Cisplatin-Based Mobilization Chemotherapy in Patients with Diffuse Large B Cell Lymphoma by Lisenko, Katharina, Cremer, Martin, Schwarzbich, Mark-Alexander, Kriegsmann, Mark, Ho, Anthony D, Witzens-Harig, Mathias, Wuchter, Patrick

“…Abstract In patients with relapsed or refractory diffuse large B cell lymphoma (DLBCL), R-DHAP (rituximab, dexamethasone, cytarabine, and cisplatin) is a…”
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Modulation of T-Cell Function and Immune Phenotype in the Microenvironment of Emu-TCL1 CLL Bearing Mice By Ibrutinib by Schwarzbich, Mark-Alexander, Romero-Toledo, Arantxa, Gribben, John G.

“…Background: Chronic lymphocytic leukaemia (CLL) is associated with global immunodeficiency, hypogammagobulinemia and T-cell exhaustion. We hypothesise that…”
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Modulation of T-Cell Function in the Microenvironment of Emu-TCL1 CLL Bearing Mice By Btki Appears Independent of ITK by Schwarzbich, Mark-Alexander, Romero-Toledo, Arantxa, Frigault, Melanie, Gribben, John G.

“…Background: Chronic lymphocytic leukemia (CLL) development is associated with global immunodeficiency including T-cell exhaustion. We hypothesise that…”
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Pre-Conditioning Serum Leptin Levels Predict Early Relapse Rates of High Risk AML after Allogeneic Stem Cell Transplantation by Schwarzbich, Mark-Alexander, Dai, Hao, Kordelas, Lambros, Beelen, Dietrich W., Radujkovic, Aleksandar, Müller-Tidow, Carsten, Dreger, Peter, Luft, Thomas

“…Background: Allogeneic stem cell transplantation (alloSCT) is an effective treatment for many hematologic diseases including intermediate- and high-risk acute…”
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High VEGF Serum Levels on Days +50 and +100 after Allogeneic Stem Cell Transplantation Predict Severe Chronic GvHD by Schwarzbich, Mark-Alexander, Nicola, Lehners, Schmidt, Katharina, Falk, Christine, Ho, Anthony D., Dreger, Peter, Luft, Thomas

“…Introduction Severe chronic graft versus host disease (cGvHD) is one of the main complications following allogeneic stem cell transplantation (SCT) and a major…”
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Targeting Pd-L1/ Pd-1-Mediated Inhibitory Signaling with Btk Inhibitors in Chronic Lymphocytic Leukemia (Cll) by Schwarzbich, Mark-Alexander

“…Chronic lymphocytic leukemia (CLL) is the most frequent leukemia in adults in the West. An unmet need for equally curative and tolerable treatment approaches…”
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Minimal Renal Toxicity after Rituximab DHAP with a Modified Cisplatin Application Scheme in Patients with Relapsed and Refractory Diffuse Large B-Cell Lymphoma by Lisenko, Katharina, McClanahan, Fabienne, Schöning, Tilman, Schwarzbich, Mark-Alexander, Cremer, Martin, Dittrich, Tobias, Ho, Anthony D., Witzens-Harig, Mathias

“…Rituximab (R) in combination with DHAP is a widely accepted salvage regimen in patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL). DHAP…”
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Rituximab, Age and High Dose Therapy Followed By Autologus Stem Cell Transplantation Are Independent Prognostic Factors for Survival in the First Line Treatment of Primary CNS-Lymphoma by Madle, Michael, Herth, Isabelle, Lehners, Nicola, Schwarzbich, Mark-Alexander, Wuchter, Patrick, Egerer, Gerlinde, Ho, Anthony D., Witzens-Harig, Mathias

“…Introduction: For patients with diffuse large B-cell lymphoma without the involvement of the CNS, the addition of rituximab to standard chemotherapy has…”
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Female Donors Are Associated with an Increased Risk of Chronic Graft-Versus-Host Disease (cGVHD) Independent of Recipient Sex but Provide Superior Graft-Versus-Leukemia Activity Once cGVHD Is Established by Lehners, Nicola, Schwarzbich, Mark-Alexander, Schmidt, Katharina, Puthenparambil, Joe, Radujkovic, Aleksandar, Dietrich, Sascha, Ho, Anthony D, Dreger, Peter, Luft, Thomas

“…Background: Chronic graft-versus-host disease (cGVHD) is a frequent complication after allogeneic stem cell transplantation (SCT). In its severe form, cGVHD…”
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