Search Results - "Schwarz, Lindsay A"

Organization of the Locus Coeruleus-Norepinephrine System by Schwarz, Lindsay A., Luo, Liqun

“…The release of the neurotransmitter norepinephrine throughout the mammalian brain is important for modulating attention, arousal, and cognition during many…”
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Viral-genetic tracing of the input–output organization of a central noradrenaline circuit by Schwarz, Lindsay A., Miyamichi, Kazunari, Gao, Xiaojing J., Beier, Kevin T., Weissbourd, Brandon, DeLoach, Katherine E., Ren, Jing, Ibanes, Sandy, Malenka, Robert C., Kremer, Eric J., Luo, Liqun

“…To better understand the relationship between input and output connectivity for neurons of interest in specific brain regions, a viral-genetic tracing approach…”
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Redefining Noradrenergic Neuromodulation of Behavior: Impacts of a Modular Locus Coeruleus Architecture by Chandler, Dan J, Jensen, Patricia, McCall, Jordan G, Pickering, Anthony E, Schwarz, Lindsay A, Totah, Nelson K

“…The locus coeruleus (LC) is a seemingly singular and compact neuromodulatory nucleus that is a prominent component of disparate theories of brain function due…”
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High-throughput dual-colour precision imaging for brain-wide connectome with cytoarchitectonic landmarks at the cellular level by Gong, Hui, Xu, Dongli, Yuan, Jing, Li, Xiangning, Guo, Congdi, Peng, Jie, Li, Yuxin, Schwarz, Lindsay A., Li, Anan, Hu, Bihe, Xiong, Benyi, Sun, Qingtao, Zhang, Yalun, Liu, Jiepeng, Zhong, Qiuyuan, Xu, Tonghui, Zeng, Shaoqun, Luo, Qingming

“…The precise annotation and accurate identification of neural structures are prerequisites for studying mammalian brain function. The orientation of neurons and…”
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Third-generation rabies viral vectors have low toxicity and improved efficiency as retrograde labeling tools by Schwarz, Lindsay A

“…In this issue of Cell Reports Methods, Jin et al. report the generation and validation of a rabies variant, RVΔL, for projection-based neuronal labeling. RVΔL…”
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Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway by Schwarz, Lindsay A, Hall, Benjamin J, Patrick, Gentry N

“…The accurate trafficking of AMPA receptors (AMPARs) to and from the synapse is a critical component of learning and memory in the brain, whereas dysfunction of…”
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Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome by Huang, Wei-Hsiang, Guenthner, Casey J., Xu, Jin, Nguyen, Tiffany, Schwarz, Lindsay A., Wilkinson, Alex W., Gozani, Or, Chang, Howard Y., Shamloo, Mehrdad, Luo, Liqun

“…Haploinsufficiency of Retinoic Acid Induced 1 (RAI1) causes Smith-Magenis syndrome (SMS), which is associated with diverse neurodevelopmental and behavioral…”
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Regulation of the Proteasome by Neuronal Activity and Calcium/Calmodulin-dependent Protein Kinase II by Djakovic, Stevan N., Schwarz, Lindsay A., Barylko, Barbara, DeMartino, George N., Patrick, Gentry N.

“…Protein degradation via the ubiquitin proteasome system has been shown to regulate changes in synaptic strength that underlie multiple forms of synaptic…”
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A genome-wide library of MADM mice for single-cell genetic mosaic analysis by Contreras, Ximena, Amberg, Nicole, Davaatseren, Amarbayasgalan, Hansen, Andi H., Sonntag, Johanna, Andersen, Lill, Bernthaler, Tina, Streicher, Carmen, Heger, Anna, Johnson, Randy L., Schwarz, Lindsay A., Luo, Liqun, Rülicke, Thomas, Hippenmeyer, Simon

“…Mosaic analysis with double markers (MADM) offers one approach to visualize and concomitantly manipulate genetically defined cells in mice with single-cell…”
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Synaptic strength is bidirectionally controlled by opposing activity-dependent regulation of Nedd4-1 and USP8 by Scudder, Samantha L, Goo, Marisa S, Cartier, Anna E, Molteni, Alice, Schwarz, Lindsay A, Wright, Rebecca, Patrick, Gentry N

“…The trafficking of AMPA receptors (AMPARs) to and from synapses is crucial for synaptic plasticity. Previous work has demonstrated that AMPARs undergo…”
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Brain Circuit of Claustrophobia-like Behavior in Mice Identified by Upstream Tracing of Sighing by Li, Peng, Li, Shi-Bin, Wang, Xuenan, Phillips, Chrystian D., Schwarz, Lindsay A., Luo, Liqun, de Lecea, Luis, Krasnow, Mark A.

“…Emotions are distinct patterns of behavioral and physiological responses triggered by stimuli that induce different brain states. Elucidating the circuits is…”
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Coordinated cadherin functions sculpt respiratory motor circuit connectivity by Vagnozzi, Alicia N, Moore, Matthew T, Lin, Minshan, Brozost, Elyse M, Kc, Ritesh, Agarwal, Aambar, Schwarz, Lindsay A, Duan, Xin, Zampieri, Niccolò, Landmesser, Lynn T, Philippidou, Polyxeni

“…Breathing, and the motor circuits that control it, is essential for life. At the core of respiratory circuits are Dbx1-derived interneurons, which generate the…”
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Breathing control center neurons that promote arousal in mice by Yackle, Kevin, Schwarz, Lindsay A., Kam, Kaiwen, Sorokin, Jordan M., Huguenard, John R., Feldman, Jack L., Luo, Liqun, Krasnow, Mark A.

“…Slow, controlled breathing has been used for centuries to promote mental calming, and it is used clinically to suppress excessive arousal such as panic…”
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A single-vector intersectional AAV strategy for interrogating cellular diversity and brain function by Hughes, Alex C., Pittman, Brittany G., Xu, Beisi, Gammons, Jesse W., Webb, Charis M., Nolen, Hunter G., Chapman, Phillip, Bikoff, Jay B., Schwarz, Lindsay A.

“…As discovery of cellular diversity in the brain accelerates, so does the need for tools that target cells based on multiple features. Here we developed…”
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The cold‐sensing ion channel TRPM8 regulates central and peripheral clockwork and the circadian oscillations of body temperature by Reimúndez, Alfonso, Fernández‐Peña, Carlos, Ordás, Purificación, Hernández‐Ortego, Pablo, Gallego, Rosalía, Morenilla‐Palao, Cruz, Navarro, Juan, Martín‐Cora, Francisco, Pardo‐Vázquez, José Luís, Schwarz, Lindsay A., Arce, Victor, Viana, Félix, Señarís, Rosa

“…Aim Physiological functions in mammals show circadian oscillations, synchronized by daily cycles of light and temperature. Central and peripheral clocks…”
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Ubiquitin-dependent endocytosis, trafficking and turnover of neuronal membrane proteins by Schwarz, Lindsay A., Patrick, Gentry N.

“…Extracellular signaling between cells is often transduced via receptors that reside at the cell membrane. In neurons this receptor-mediated signaling can…”
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Enhancement of Transgene Expression by Combining Glucocorticoids and Anti-mitotic Agents during Transient Transfection Using DNA-Cationic Liposomes by Nair, Rajesh R., Rodgers, John R., Schwarz, Lindsay A.

“…The anti-mitotic drugs colchicine and paclitaxel increase transfection efficiency of cationic liposomes. Using combined lipid-mediated transfection with…”
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The presence of β2-adrenoceptors sensitizes α2A-adrenoceptors to desensitization after chronic epinephrine treatment by Bawa-Khalfe, Tasneem, Altememi, Ghazi F, Mandyam, Chitra D, Schwarz, Lindsay A, Eikenburg, Douglas C, Standifer, Kelly M

“…Abstract Background In addition to the regulation of blood pressure, α 2 - and β-adrenoceptor (AR) subtypes play an important role in the modulation of…”
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Prolactin receptor gene expression in lymphoid cells by O'Neal, K D, Schwarz, L A, Yu-Lee, L Y

“…To understand the role of pituitary prolactin (PRL) and its receptor (PRL-R) in the growth and differentiation of lymphoid cells, PRL-R gene expression was…”
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Viral-genetic tracing of the input–output organization of a central norepinephrine circuit by Schwarz, Lindsay A., Miyamichi, Kazunari, Gao, Xiaojing J., Beier, Kevin T., Weissbourd, Brandon, DeLoach, Katherine E., Ren, Jing, Ibanes, Sandy, Malenka, Robert C., Kremer, Eric J., Luo, Liqun

“…Deciphering how neural circuits are anatomically organized with regard to input and output is instrumental in understanding how the brain processes…”
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