Search Results - "Schwarz, Jennifer J."
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An atlas of the aging mouse proteome reveals the features of age-related post-transcriptional dysregulation
Published in Nature communications (02-10-2024)“…To what extent and how post-transcriptional dysregulation affects aging proteome remains unclear. Here, we provide proteomic data of whole-tissue lysates (WTL)…”
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A systems study reveals concurrent activation of AMPK and mTOR by amino acids
Published in Nature communications (21-11-2016)“…Amino acids (aa) are not only building blocks for proteins, but also signalling molecules, with the mammalian target of rapamycin complex 1 (mTORC1) acting as…”
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The assembly of the Mitochondrial Complex I Assembly complex uncovers a redox pathway coordination
Published in Nature communications (12-12-2023)“…The Mitochondrial Complex I Assembly (MCIA) complex is essential for the biogenesis of respiratory Complex I (CI), the first enzyme in the respiratory chain,…”
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Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif
Published in The Journal of biological chemistry (01-10-2021)“…The spike protein is the main protein component of the SARS-CoV-2 virion surface. The spike receptor-binding motif mediates recognition of the human…”
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Preventing Harm in the ICU—Building a Culture of Safety and Engaging Patients and Families
Published in Critical care medicine (01-09-2017)“…OBJECTIVE:Preventing harm remains a persistent challenge in the ICU despite evidence-based practices known to reduce the prevalence of adverse events. This…”
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Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling
Published in Life science alliance (01-11-2021)“…B cell antigen receptor (BCR) signaling is initiated by protein kinases and limited by counteracting phosphatases that currently are less well studied in their…”
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