Search Results - "Schwarz, Janett"
-
1
Serine-71 phosphorylation of Rac1 modulates downstream signaling
Published in PloS one (10-09-2012)“…The Rho GTPases Rac1 and Cdc42 regulate a variety of cellular functions by signaling to different signal pathways. It is believed that the presence of a…”
Get full text
Journal Article -
2
Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation
Published in Journal of cell science (15-10-2013)“…Cell migration is commonly accompanied by protrusion of membrane ruffles and lamellipodia. In two-dimensional migration, protrusion of these thin sheets of…”
Get full text
Journal Article -
3
Protection from Clostridium difficile toxin B-catalysed Rac1/Cdc42 glucosylation by tauroursodeoxycholic acid-induced Rac1/Cdc42 phosphorylation
Published in Biological chemistry (01-01-2012)“…Toxin A (TcdA) and toxin B (TcdB) are the major virulence factors of Clostridium difficile-associated diarrhoea (CDAD). TcdA and TcdB mono-glucosylate small…”
Get more information
Journal Article -
4
Autoproteolytic cleavage mediates cytotoxicity of Clostridium difficile toxin A
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-03-2011)“…Toxin A and toxin B from Clostridium difficile are the causative agents of the antibiotic-associated pseudomembranous colitis. They are of an A/B structure…”
Get full text
Journal Article -
5
Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formation
Published in Scientific reports (14-12-2017)“…Immuno-oncology approaches mainly utilize monoclonal antibodies or protein-based scaffolds that bind with high affinity to cancer cells and can generate an…”
Get full text
Journal Article -
6
Rac function is critical for cell migration but not required for spreading and focal adhesion formation
Published in Journal of cell science (01-01-2013)“…Cell migration is commonly accompanied by protrusion of membrane ruffles and lamellipodia. In 2D-migration, protrusion of these thin sheets of cytoplasm is…”
Get full text
Journal Article