Search Results - "Schwarz, Frederick P."

Thermal Characterization and Interaction of the Subunits from the Multimeric Bacteriophage Endolysin PlyC by Hoopes, J Todd, Heselpoth, Ryan D, Schwarz, Frederick P, Nelson, Daniel C

“…Bacteriophage endolysins degrade the bacterial peptidoglycan and are considered enzymatic alternatives to small-molecule antibiotics. In particular, the…”
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Coupling of DNA binding and helicase activity is mediated by a conserved loop in the MCM protein by Sakakibara, Nozomi, Kasiviswanathan, Rajesh, Melamud, Eugene, Han, Mimi, Schwarz, Frederick P, Kelman, Zvi

“…Minichromosome maintenance (MCM) helicases are the presumptive replicative helicases, thought to separate the two strands of chromosomal DNA during…”
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Energetic contributions to the initiation of transcription in E. coli by Ramprakash, Jayanthi, Schwarz, Frederick P.

“…The thermodynamics of RNA polymerase (RNAP) binding to a 108 base pair (bp) synthetic promoter with consensus sequences at the − 35 and − 10 bp binding regions…”
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Thermal stabilization of human albumin by medium- and short-chain n-alkyl fatty acid anions by Shrake, Andrew, Frazier, Douglas, Schwarz, Frederick P.

“…A comprehensive study of the thermal stabilization of defatted human albumin monomer by n‐alkyl fatty acid anions (FAAs), formate through n‐decanoate, was…”
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Linear Free Energy Correlations for Enzymatic Base Flipping:  How Do Damaged Base Pairs Facilitate Specific Recognition? by Krosky, Daniel J, Schwarz, Frederick P, Stivers, James T

“…To efficiently maintain their genomic integrity, DNA repair glycosylases must exhibit high catalytic specificity for their cognate damaged bases using an…”
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Estimation of the Hydrophobic Effect in an Antigen−Antibody Protein−Protein Interface by Sundberg, Eric J, Urrutia, Mariela, Braden, Bradford C, Isern, Jordi, Tsuchiya, Daisuke, Fields, Barry A, Malchiodi, Emilio L, Tormo, José, Schwarz, Frederick P, Mariuzza, Roy A

“…Antigen−antibody complexes provide useful models for analyzing the thermodynamics of protein−protein association reactions. We have employed site-directed…”
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Effects of Metal Ligation and Oxygen on the Reversibility of the Thermal Denaturation of Pseudomonas aeruginosa Azurin by Sandberg, Anders, Leckner, Johan, Shi, Ying, Schwarz, Frederick P, Karlsson, B. Göran

“…Thermodynamic equilibrium transition models in DSC are only applicable to reversible processes, but reversibility of the thermal transitions of proteins is…”
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Entropic Nature of the Interaction between Promoter Bound CRP Mutants and RNA Polymerase by Krueger, Susan, Gregurick, Susan, Shi, Ying, Wang, Shenglun, Wladkowski, Brian D, Schwarz, Frederick P

“…The interaction between CRP, T127L, S128A, and CRP* and RNA polymerase bound to a 104 bp synthetic promoter were determined by ITC at 298 K and ranges from a…”
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ATP Hydrolysis and DNA Binding Confer Thermostability on the MCM Helicase by Sakakibara, Nozomi, Schwarz, Frederick P, Kelman, Zvi

“…The minichromosome maintenance (MCM) helicase is the replicative helicase in archaea. The enzyme utilizes the energy derived from ATP hydrolysis to translocate…”
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Thermodynamics of single strand DNA base stacking by Ramprakash, Jayanthi, Lang, Brian, Schwarz, Frederick P.

“…The thermodynamics of the stacking to unstacking transitions of 24 single‐stranded DNA sequences (ssDNA), 10–12 bases in length, in sodium phosphate buffer…”
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The Role of Cys-298 in Aldose Reductase Function by Balendiran, Ganesaratnam K., Sawaya, Michael R., Schwarz, Frederick P., Ponniah, Gomathinayagam, Cuckovich, Richard, Verma, Malkhey, Cascio, Duilio

“…Diabetic tissues are enriched in an “activated” form of human aldose reductase (hAR), a NADPH-dependent oxidoreductase involved in sugar metabolism. Activated…”
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Recommendations on measurement and analysis of results obtained on biological substances using isothermal titration calorimetry (IUPAC Technical Report) by Schwarz, Frederick P., Reinisch, Timm, Hinz, Hans-Jürgen, Surolia, Avadhesha

“…Isothermal titration calorimetry (ITC) is widely used to determine the thermodynamics of biological interactions including protein-protein, small…”
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Thermodynamic dependence of DNA/DNA and DNA/RNA hybridization reactions on temperature and ionic strength by Lang, Brian E., Schwarz, Frederick P.

“…The thermodynamics of 5′-ATGCTGATGC-3′ binding to its complementary DNA and RNA strands was determined in sodium phosphate buffer under varying conditions of…”
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The role of water in the thermodynamics of drug binding to cyclodextrin by Todorova, Niya A., Schwarz, Frederick P.

“…The thermodynamic parameters, Δ B G ∘, Δ B H ∘, Δ B S ∘, and Δ B C p , of the drugs flurbiprofen (FLP), nabumetone (NAB), and naproxen (NPX) binding to…”
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Effect of the phosphate substrate on drug-inhibitor binding to human purine nucleoside phosphorylase by Todorova, Niya A., Schwarz, Frederick P.

“…The thermodynamics of the drug-inhibitors acyclovir, ganciclovir, and 9-benzylguanine binding to human purine nucleoside phosphorylase (hsPNP) were determined…”
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Thermodynamic and Nuclear Magnetic Resonance Study of the Interactions of .alpha.- and .beta.-Cyclodextrin with Model Substances: Phenethylamine, Ephedrines, and Related Substances by Rekharsky, Mikhail V, Goldberg, Robert N, Schwarz, Frederick P, Tewari, Yadu B, Ross, Philip D, Yamashoji, Yuko, Inoue, Yoshihisa

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High-resolution Crystal Structures of Erythrina cristagalli Lectin in Complex with Lactose and 2′-α- l-Fucosyllactose and Correlation with Thermodynamic Binding Data by Svensson, Cecilia, Teneberg, Susann, Nilsson, Carol L., Kjellberg, Anders, Schwarz, Frederick P., Sharon, Nathan, Krengel, Ute

“…The primary sequence of Erythrina cristagalli lectin (ECL) was mapped by mass spectrometry, and the crystal structures of the lectin in complex with lactose…”
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Importance of product/reactant equilibration in the kinetics of the phosphoglucose isomerization reaction by differential stopped flow microcalorimetry by Stödeman, Magnus, Schwarz, Frederick P.

“…The kinetics for the isomerization of fructose-6-phosphate to glucose-6-phosphate (F6P → G6P) by baker’s yeast phosphoglucose isomerase (PGI) with regard to k…”
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Measurement and analysis of results obtained on biological substances with differential scanning calorimetry (IUPAC Technical Report) by Hinz, Hans-Jürgen, Schwarz, Frederick P.

“…Differential scanning calorimeters (DSCs) have been widely used to determine the thermodynamics of phase transitions and conformational changes in biological…”
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Thermodynamic comparison of PNA/DNA and DNA/DNA hybridization reactions at ambient temperature by Schwarz, Frederick P., Robinson, Scott, Butler, John M.

“…The thermodynamics of 13 hybridization reactions between 10 base DNA sequences of design 5′-ATGCXYATGC-3′ with X, Y = A, C, G, T and their complementary PNA…”
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