Search Results - "Schwartz, Tyler"
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Early Audiometric Intervention in Bacterial Meningitis: Cochlear Implantation in a 10-Week-Old Child
Published in Pediatrics (Evanston) (01-08-2024)“…Sensorineural hearing loss is a well-known complication of Streptococcus pneumoniae meningitis. Given the propensity for fibrosis and ossification of the…”
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Systemic corticosteroids for orbital complications of pediatric rhinosinusitis: A systematic review
Published in International journal of pediatric otorhinolaryngology (01-04-2023)“…Determine if systemic corticosteroids administration is associated with reduced length of stay, surgical intervention, and abscess formation in pediatric…”
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Langerhans Cell Histiocytosis of the Head and Neck: Experience at a Rural Tertiary Referral Center
Published in Annals of otology, rhinology & laryngology (01-04-2023)“…Objectives: Retrospectively analyze head and neck Langerhans Cell Histiocytosis at a rural tertiary referral center and compare results with previously…”
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Metastatic renal cell carcinoma to the thyroid with cervicothoracic venous tumor thrombosis
Published in Head & neck (01-07-2023)“…Introduction Metastatic renal cell carcinoma (RCC) represents 25%–42% of metastatic thyroid malignancies. Propensity for RCC to demonstrate intravascular…”
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Gray-Scale Inversion on High Resolution Computed Tomography of the Temporal Bone: An Observational Study
Published in Annals of otology, rhinology & laryngology (01-10-2021)“…Objectives: This is a qualitative study to explore the utility of gray-scale inversion or the “invert” function of high-resolution computed tomography (HRCT)…”
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Transcanal incision and drainage of a parapharyngeal abscess in a pediatric patient: A novel technique
Published in International journal of pediatric otorhinolaryngology (01-09-2018)“…The disease of parapharyngeal abscess is well known to the otolaryngologist and is commonly managed via transoral, transcervical, or combined incision and…”
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Contralateral Gluteal Compartment Syndrome After Prolonged Use of a Fracture Table in a Scissoring Position: A Case Report
Published in JBJS case connector (01-07-2023)“…A 62-year-old Caucasian man presented with a comminuted subtrochanteric fracture after a low-energy fall. Physical examination postoperatively revealed a firm…”
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Green building standards and the United Nations’ Sustainable Development Goals
Published in Journal of environmental management (15-01-2023)“…Sustainable practices in the building industry are strongly influenced by published green and sustainable building and real-estate standards (GSBRES)…”
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Monoclonal antibodies: Trends in therapeutic success and commercial focus
Published in Drug discovery today (01-01-2023)“…•More than 100 new experimental antibodies now enter into development each year.•Half of experimental monoclonal antibodies and a third of approvals are…”
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Antibiotic Development: Lessons from the Past and Future Opportunities
Published in Pharmaceutical research (01-05-2024)“…The challenge of antimicrobial resistance is broadly appreciated by the clinical and scientific communities. To assess progress in the development of medical…”
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2023 in review: FDA approvals of new medicines
Published in Drug discovery today (01-05-2024)“…•2023 tied with 1996 as the year with the greatest number of new entities approved by the FDA.•Cancers have long been dominant as the target for new medicines,…”
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2022 in review: FDA approvals of new medicines
Published in Drug discovery today (01-08-2023)“…•The forty-four approvals by FDA in 2022 fell below recent rates but is within the long-term average.•Approvals for orphan indications captured more than half…”
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2021 in review: FDA approvals of new medicines
Published in Drug discovery today (01-08-2022)“…•The sixty NME approvals by FDA in 2021 was tied for the highest in post-PDUFA history.•NMEs approved for orphan indications or with an expedited or priority…”
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Immunoconjugates and bispecific antibodies: Trends in therapeutic success and commercial focus
Published in Drug discovery today (01-03-2023)“…•Immunoconjugates and bispecific antibodies are rapidly gainin in popularity.•Most immunoconjugates and bsAbs are developed for the treatment of cancer.•A…”
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Sources of innovation for new medicines: questions of sustainability
Published in Drug discovery today (01-01-2021)“…•Company formation peaked in the early 2000s, declining after the 2008 downturn.•Company departures (mergers, bankruptcies & quitting research) have steadily…”
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2020 in review: FDA approvals of new medicines
Published in Drug discovery today (01-12-2021)“…•Despite a disruptive pandemic, the FDA approved 55 NMEs in 2020, the third highest rate ever.•Orphan approvals surged to capture 60% of NMEs approved in…”
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2019 in review: FDA approvals of new medicines
Published in Drug discovery today (01-11-2020)“…•The FDA approved 53 NMEs in 2019, below the prior year but higher than the five year average.•The use of the Orphan Drug Act shrank by a third, both in…”
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Inter-individual variability during neurodevelopment: an investigation of linear and nonlinear resting-state EEG features in an age-homogenous group of infants
Published in Cerebral cortex (New York, N.Y. 1991) (20-06-2023)“…Abstract Electroencephalography measures are of interest in developmental neuroscience as potentially reliable clinical markers of brain function. Features…”
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Expanding roles for academic entrepreneurship in drug discovery
Published in Drug discovery today (01-11-2020)“…•Academic inventors or founders are responsible for nearly a third of NMEs approved since 2001.•The contributions of academia have progressively increased over…”
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