Search Results - "Schwartz, Olivier"
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Biology and pathogenesis of chikungunya virus
Published in Nature reviews. Microbiology (01-07-2010)“…Key Points Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that provokes arthralgia and, potentially, severe complications in humans. A…”
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Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells
Published in Nature communications (25-03-2021)“…Extracellular vesicles (EVs), including exosomes, are thought to mediate intercellular communication through the transfer of cargoes from donor to acceptor…”
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Syncytia formation by SARS‐CoV‐2‐infected cells
Published in The EMBO journal (01-12-2020)“…Severe cases of COVID‐19 are associated with extensive lung damage and the presence of infected multinucleated syncytial pneumocytes. The viral and cellular…”
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Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization
Published in Nature (London) (12-08-2021)“…The SARS-CoV-2 B.1.617 lineage was identified in October 2020 in India 1 – 5 . Since then, it has become dominant in some regions of India and in the UK, and…”
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IgA dominates the early neutralizing antibody response to SARS-CoV-2
Published in Science translational medicine (20-01-2021)“…Humoral immune responses are typically characterized by primary IgM antibody responses followed by secondary antibody responses associated with immune memory…”
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More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteins
Published in Retrovirology (21-11-2017)“…The first responders of human antiviral immunity are components of the intrinsic immune response that reside within each and every one of our cells. This…”
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Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies
Published in Nature Medicine (01-06-2022)“…The severe acute respiratory syndrome coronavirus 2 Omicron BA.1 sublineage has been supplanted in many countries by the BA.2 sublineage. BA.2 differs from…”
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SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx
Published in Nature (London) (30-06-2011)“…How macrophages avoid HIV-1 infection HIV-1 is unable to replicate efficiently in dendritic cells, the antigen-presenting tissue cells that function in both…”
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Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies
Published in Nature communications (14-02-2023)“…Convergent evolution of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 lineages has led to the emergence of several new subvariants, including BA.2.75.2, BA.4.6. and…”
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They Might Be Giants: Does Syncytium Formation Sink or Spread HIV Infection?
Published in PLoS pathogens (02-02-2017)“…The capacity to form syncytia in T cell lines was adopted as an early classification system (syncytia-inducing [SI] versus non-syncytia-inducing [NSI]) to…”
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Elimination of HIV-1-infected cells by broadly neutralizing antibodies
Published in Nature communications (03-03-2016)“…The Fc region of HIV-1 Env-specific broadly neutralizing antibodies (bNAbs) is required for suppressing viraemia, through mechanisms which remain poorly…”
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Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2
Published in Science (American Association for the Advancement of Science) (30-07-2021)“…Repurposing drugs as treatments for COVID-19, the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has drawn much attention…”
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The entanglement between flaviviruses and ER-shaping proteins
Published in PLoS pathogens (01-04-2020)“…Rotavirus, vaccinia virus (VV), hepatitis C virus (HCV), as well as members of the Flavivirus genus—dengue virus (DENV), West Nile virus(WNV), yellow fever…”
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Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses
Published in Cell reports (Cambridge) (10-01-2017)“…ZIKA virus (ZIKV) is an emerging pathogen responsible for neurological disorders and congenital microcephaly. However, the molecular basis for ZIKV…”
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Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection
Published in Nature immunology (01-11-2021)“…Coordinated local mucosal and systemic immune responses following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection either protect against…”
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The TIM and TAM Families of Phosphatidylserine Receptors Mediate Dengue Virus Entry
Published in Cell host & microbe (18-10-2012)“…Dengue viruses (DVs) are responsible for the most medically relevant arboviral diseases. However, the molecular interactions mediating DV entry are poorly…”
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Synthesis and characterization of electroactive PEDOT-TEMPO polymers as potential cathode materials in rechargeable batteries
Published in Synthetic metals (01-09-2018)“…•PEDOT-TEMPO polymers were synthesized and tested as organic cathodes in batteries.•TEMPO moieties were chemically linked to 3,4-ethylenedioxythiophene via…”
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Modeling the kinetics of the neutralizing antibody response against SARS-CoV-2 variants after several administrations of Bnt162b2
Published in PLoS computational biology (07-08-2023)“…Because SARS-CoV-2 constantly mutates to escape from the immune response, there is a reduction of neutralizing capacity of antibodies initially targeting the…”
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STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses
Published in Cell metabolism (04-01-2022)“…Concerted alteration of immune and metabolic homeostasis underlies several inflammation-related pathologies, ranging from metabolic syndrome to infectious…”
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HIV-1 cell-to-cell transmission and broadly neutralizing antibodies
Published in Retrovirology (28-07-2018)“…HIV-1 spreads through contacts between infected and target cells. Polarized viral budding at the contact site forms the virological synapse. Additional…”
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