Search Results - "Schwartz, Erich"
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Diffuse high intensity PD-L1 staining in thymic epithelial tumors
Published in Journal of thoracic oncology (01-03-2015)“…Blockade of the immune checkpoint programmed death receptor ligand-1 (PD-L1)/PD-1 pathway has well-established clinical activity across many tumor types. PD-L1…”
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2
Molecular profiling of single circulating tumor cells from lung cancer patients
Published in Proceedings of the National Academy of Sciences - PNAS (27-12-2016)“…Circulating tumor cells (CTCs) are established cancer biomarkers for the “liquid biopsy” of tumors. Molecular analysis of single CTCs, which recapitulate…”
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Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips
Published in Lab on a chip (07-01-2014)“…Detection and characterization of circulating tumor cells (CTCs) may reveal insights into the diagnosis and treatment of malignant disease. Technologies for…”
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The Vascular Marker CD31 Also Highlights Histiocytes and Histiocyte-Like Cells Within Cutaneous Tumors
Published in American journal of clinical pathology (01-02-2015)“…Objectives: While useful in diagnosing angiosarcomas, CD31 can also highlight histiocytes within soft tissue tumors and lead to errors in diagnosis. We sought…”
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PRC2/EED-EZH2 complex is up-regulated in breast cancer lymph node metastasis compared to primary tumor and correlates with tumor proliferation in situ
Published in PloS one (10-12-2012)“…Lymph node metastasis is a key event in the progression of breast cancer. Therefore it is important to understand the underlying mechanisms which facilitate…”
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Spatial organization of dendritic cells within tumor draining lymph nodes impacts clinical outcome in breast cancer patients
Published in Journal of translational medicine (02-10-2013)“…Dendritic cells (DCs) are important mediators of anti-tumor immune responses. We hypothesized that an in-depth analysis of dendritic cells and their spatial…”
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Quantitative, architectural analysis of immune cell subsets in tumor-draining lymph nodes from breast cancer patients and healthy lymph nodes
Published in PloS one (25-08-2010)“…To date, pathological examination of specimens remains largely qualitative. Quantitative measures of tissue spatial features are generally not captured. To…”
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Expression of CD163 (hemoglobin scavenger receptor) in normal tissues, lymphomas, carcinomas, and sarcomas is largely restricted to the monocyte/macrophage lineage
Published in The American journal of surgical pathology (01-05-2005)“…CD163, a hemoglobin scavenger receptor, is expressed in monocytes and macrophages. We tested the expression of the CD163 protein in 1,105 human malignancies…”
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Altered local and systemic immune profiles underlie lymph node metastasis in breast cancer patients
Published in International journal of cancer (01-06-2013)“…Cancer‐mediated immune dysfunction contributes to tumor progression and correlates with patient outcome. Metastasis to tumor draining lymph nodes (TDLNs) is an…”
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10
Adenomatoid tumors of the female and male genital tracts: a clinicopathological and immunohistochemical study of 44 cases
Published in Modern pathology (01-09-2009)“…Adenomatoid tumors of the female and male genital tracts are well characterized as mesothelial in origin, but a detailed histological and immunohistochemical…”
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A clinical trial of lovastatin for modification of biomarkers associated with breast cancer risk
Published in Breast cancer research and treatment (01-11-2013)“…Pre-clinical and epidemiologic studies provide rationale for evaluating lipophilic statins for breast cancer prevention. We conducted a single-arm, biomarker…”
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12
Computed Tomography Features associated With the Eighth Edition TNM Stage Classification for Thymic Epithelial Tumors
Published in Journal of thoracic imaging (01-05-2018)“…PURPOSE:The eighth edition of the TNM classification of malignant tumors for the first time includes an official staging system for thymic epithelial tumors…”
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13
Immunohistochemical Characterization of Nasal-Type Extranodal NK/T-Cell Lymphoma Using a Tissue Microarray : An Analysis of 84 Cases
Published in American journal of clinical pathology (01-09-2008)“…Nasal-type extranodal natural killer (NK)/T-cell lymphoma is an uncommon malignancy. By using a tissue microarray, we characterized 84 cases of extranodal…”
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14
A comparative analysis of cutaneous marginal zone lymphoma and cutaneous chronic lymphocytic leukemia
Published in The American journal of dermatopathology (01-02-2012)“…The morphologic distinction between cutaneous marginal zone lymphoma (CMZL) and secondary cutaneous involvement by B-cell chronic lymphocytic leukemia (B-CLL)…”
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15
Sentinel lymph node B cells can predict disease-free survival in breast cancer patients
Published in NPJ breast cancer (23-08-2018)“…Tumor invasion into draining lymph nodes, especially sentinel lymph nodes (SLNs), is a key determinant of prognosis and treatment in breast cancer as part of…”
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CD163 Expression Is Present in Cutaneous Histiocytomas but Not in Atypical Fibroxanthomas
Published in American journal of clinical pathology (01-06-2010)“…CD163, a hemoglobin scavenger receptor, is expressed in monocytes and macrophages. Recent work has shown that this marker is specific for neoplasms of…”
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A Phase II Study of Gefitinib, 5-Fluorouracil, Leucovorin, and Oxaliplatin in Previously Untreated Patients with Metastatic Colorectal Cancer
Published in Clinical cancer research (01-11-2008)“…Purpose: We investigated the gefitinib, 5-fluorouracil (5-FU), leucovorin and oxaliplatin (IFOX) regimen as first-line therapy in patients with metastatic…”
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Discordant Immunophenotypic Profiles of Adhesion Molecules and Cytokines in Acute Myeloid Leukemia Involving Bone Marrow and Skin
Published in American journal of clinical pathology (01-08-2012)“…We investigated the role of adhesion molecules in skin involvement by acute myeloid leukemia (AML) using immunohistochemical analysis. Ten paired cases of skin…”
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Cytotoxic T lymphocyte responses against melanocytes and melanoma
Published in Journal of translational medicine (27-07-2011)“…Vitiligo is a common toxicity associated with immunotherapy for melanoma. Cytotoxic T lymphocytes (CTLs) against melanoma commonly target melanoma-associated…”
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Pruritus as a Paraneoplastic Symptom of Thymoma
Published in Journal of thoracic oncology (01-11-2015)Get more information
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