Search Results - "Schwartz, Elisabeth F."

Insulin Release Mechanism Modulated by Toxins Isolated from Animal Venoms: From Basic Research to Drug Development Prospects by Sarmiento, Beatriz Elena, Santos Menezes, Luis Felipe, Schwartz, Elisabeth F

“…Venom from mammals, amphibians, snakes, arachnids, sea anemones and insects provides diverse sources of peptides with different potential medical applications…”
Get full text

Protease inhibitors from marine venomous animals and their counterparts in terrestrial venomous animals by Mourão, Caroline B F, Schwartz, Elisabeth F

“…The Kunitz-type protease inhibitors are the best-characterized family of serine protease inhibitors, probably due to their abundance in several organisms…”
Get full text

The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening by Camargos, Thalita S, Bosmans, Frank, Rego, Solange C, Mourão, Caroline B F, Schwartz, Elisabeth F

“…We identified Tf2, the first β-scorpion toxin from the venom of the Brazilian scorpion Tityus fasciolatus. Tf2 is identical to Tb2-II found in Tityus…”
Get full text

Identification and phylogenetic analysis of Tityus pachyurus and Tityus obscurus novel putative Na+-channel scorpion toxins by Guerrero-Vargas, Jimmy A, Mourão, Caroline B F, Quintero-Hernández, Verónica, Possani, Lourival D, Schwartz, Elisabeth F

“…Colombia and Brazil are affected by severe cases of scorpionism. In Colombia the most dangerous accidents are caused by Tityus pachyurus that is widely…”
Get full text

Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones) by Schwartz, Elisabeth F, Diego-Garcia, Elia, Rodríguez de la Vega, Ricardo C, Possani, Lourival D

“…Scorpions like other venomous animals possess a highly specialized organ that produces, secretes and disposes the venom components. In these animals, the last…”
Get full text

Activity of Scorpion Venom-Derived Antifungal Peptides against Planktonic Cells of Candida spp. and Cryptococcus neoformans and Candida albicans Biofilms by Guilhelmelli, Fernanda, Vilela, Nathália, Smidt, Karina S, de Oliveira, Marco A, da Cunha Morales Álvares, Alice, Rigonatto, Maria C L, da Silva Costa, Pedro H, Tavares, Aldo H, de Freitas, Sônia M, Nicola, André M, Franco, Octávio L, Derengowski, Lorena da Silveira, Schwartz, Elisabeth F, Mortari, Márcia R, Bocca, Anamélia L, Albuquerque, Patrícia, Silva-Pereira, Ildinete

“…The incidence of fungal infections has been increasing in the last decades, while the number of available antifungal classes remains the same. The natural and…”
Get full text

Antimicrobial and Chemotactic Activity of Scorpion-Derived Peptide, ToAP2, against Mycobacterium massiliensis by Marques-Neto, Lázaro M, Trentini, Monalisa M, das Neves, Rogério C, Resende, Danilo P, Procopio, Victor O, da Costa, Adeliane C, Kipnis, André, Mortari, Márcia R, Schwartz, Elisabeth F, Junqueira-Kipnis, Ana Paula

“…is a rapid growing, multidrug-resistant, non-tuberculous mycobacteria that is responsible for a wide spectrum of skin and soft tissue infections, as well as…”
Get full text

Arthropod venoms: A vast arsenal of insecticidal neuropeptides by Schwartz, Elisabeth F., Mourão, Caroline B. F., Moreira, Karla G., Camargos, Thalita S., Mortari, Márcia R.

“…Arthropods are the most diverse animal group on the planet, and occupy almost all ecological niches. Venomous arthropods are a rich source of bioactive…”
Get full text

Cloning and characterization of cDNA sequences encoding for new venom peptides of the Brazilian scorpion Opisthacanthus cayaporum by Silva, Édelyn C.N., Camargos, Thalita S., Maranhão, Andrea Q., Silva-Pereira, Ildinete, Silva, Luciano P., Possani, Lourival D., Schwartz, Elisabeth F.

“…Scorpion venom glands produce a large variety of bioactive peptides. This communication reports the identification of venom components obtained by sequencing…”
Get full text

Venomic and pharmacological activity of Acanthoscurria paulensis (Theraphosidae) spider venom by Mourão, Caroline Barbosa F., Oliveira, Fagner Neves, e Carvalho, Andréa C., Arenas, Claudia J., Duque, Harry Morales, Gonçalves, Jacqueline C., Macêdo, Jéssica K.A., Galante, Priscilla, Schwartz, Carlos A., Mortari, Márcia R., Almeida Santos, Maria de Fátima M., Schwartz, Elisabeth F.

“…In the present study we conducted proteomic and pharmacological characterizations of the venom extracted from the Brazilian tarantula Acanthoscurria paulensis,…”
Get full text

Bites Caused by Giant Water Bugs Belonging to Belostomatidae Family (Hemiptera, Heteroptera) in Humans: A Report of Seven Cases by Haddad, Vidal, Schwartz, Elisabeth F., Schwartz, Carlos Alberto, Carvalho, Lucélia Nobre

“…We report 7 cases of patients bitten by giant water bugs, large predatory insects belonging to the Belostomatidae family (Hemiptera, Heteroptera). These…”
Get full text

Mining on scorpion venom biodiversity by Rodríguez de la Vega, Ricardo C., Schwartz, Elisabeth F., Possani, Lourival D.

“…Scorpion venoms are complex mixtures of dozens or even hundreds of distinct proteins, many of which are inter-genome active elements. Fifty years after the…”
Get full text

Head-to-Tail Cyclization after Interaction with Trypsin: A Scorpion Venom Peptide that Resembles Plant Cyclotides by Mourão, Caroline B. F, Brand, Guilherme D, Fernandes, João Paulo C, Prates, Maura V, Bloch, Carlos, Barbosa, João Alexandre R. G, Freitas, Sônia M, Restano-Cassulini, Rita, Possani, Lourival D, Schwartz, Elisabeth F

“…Peptidase inhibitors (PIs) have been broadly studied due to their wide therapeutic potential for human diseases. A potent trypsin inhibitor from Tityus…”
Get full text

Towards Therapeutic Applications of Arthropod Venom K^+-Channel Blockers in CNS Neurologic Diseases Involving Memory Acquisition and Storage by Gati, Christiano D. C., Mortari, Márcia R., Schwartz, Elisabeth F.

“…Potassium channels are the most heterogeneous and widely distributed group of ion channels and play important functions in all cells, in both normal and…”
Get full text

Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom by Galante, Priscilla, Campos, Gabriel A. A., Moser, Jacqueline C. G., Martins, Danubia B., dos Santos Cabrera, Marcia P., Rangel, Marisa, Coelho, Luiza C., Simon, Karina S., Amado, Veronica M., de A. I. Muller, Jessica, Koehbach, Johannes, Lohman, Rink-Jan, Cabot, Peter J., Vetter, Irina, Craik, David J., Toffoli-Kadri, Monica C., Monge-Fuentes, Victoria, Goulart, Jair T., Schwartz, Elisabeth F., Silva, Luciano P., Bocca, Anamelia L., Mortari, Márcia R.

“…Animal venoms are rich sources of neuroactive compounds, including anti-inflammatory, antiepileptic, and antinociceptive molecules. Our study identified a…”
Get full text

Antiretroviral and cytotoxic activities of Tityus obscurus synthetic peptide by Mata, Elida C. G., Ombredane, Alicia, Joanitti, Graziella A., Kanzaki, L. I. B., Schwartz, Elisabeth F.

“…New drugs are constantly in demand, and nature's biodiversity is a rich source of new compounds for therapeutic applications. Synthetic peptides based on the…”
Get full text

OcyKTx2, a new K+-channel toxin characterized from the venom of the scorpion Opisthacanthus cayaporum by Schwartz, Elisabeth F., Bartok, Adam, Schwartz, Carlos Alberto, Papp, Ferenc, Gómez-Lagunas, Froylan, Panyi, Gyorgy, Possani, Lourival D.

“…•OcyKTx2 is a new alpha-KTx6 isolated from the venom of a Liochelidae scorpion.•OcyKTx2 reversibly blocks Shaker B K+-channels with Kd of 82nM.•OcyKTx2 blocks…”
Get full text

First report of the characterization of the pathophysiological mechanisms caused by the freshwater catfish Pimelodus maculatus (order: Siluriformes) by Sarmiento, Beatriz Elena, Rangel, Marisa, Gonçalves, Jacqueline Coimbra, Pereira, Lilibete, Rego, Solange, Campos, Leandro Ambrósio, Haddad, Vidal, Mortari, Márcia Renata, Schwartz, Elisabeth F.

“…Injuries caused by aquatic animals in Brazil in most cases are provoked by marine and freshwater catfish. Pimelodus maculatus is a freshwater catfish very…”
Get full text

Non-disulfide-Bridge Peptide 5.5 from the Scorpion Hadrurus gertschi Inhibits the Growth of Mycobacterium abscessus subsp. massiliense by Trentini, Monalisa M, das Neves, Rogério C, Santos, Bruno de Paula Oliveira, DaSilva, Roosevelt A, de Souza, Adolfo C Barros, Mortari, Márcia R, Schwartz, Elisabeth F, Kipnis, André, Junqueira-Kipnis, Ana P

“…Multi-drug resistant microorganisms have been a growing concern during the last decades due to their contribution in mortality rates worldwide. Antimicrobial…”
Get full text

Molecular cloning and nucleotide sequence analysis of genes from a cDNA library of the scorpion Tityus discrepans by D'Suze, Gina, Schwartz, Elisabeth F., García-Gómez, B.I., Sevcik, Carlos, Possani, Lourival D.

“…Tityus discrepans is a Venezuelan scorpion known to cause severe human envenomations. It contains toxins that impair proper ion channels function, affect…”
Get full text