Search Results - "Schwartz, Dean"

A macrocyclic quinol-containing ligand enables high catalase activity even with a redox-inactive metal at the expense of the ability to mimic superoxide dismutase by Karbalaei, Sana, Franke, Alicja, Oppelt, Julian, Aziz, Tarfi, Jordan, Aubree, Pokkuluri, P. Raj, Schwartz, Dean D, Ivanovi -Burmazovi, Ivana, Goldsmith, Christian R

“…Previously, we found that linear quinol-containing ligands could allow manganese complexes to act as functional mimics of superoxide dismutase (SOD). The redox…”
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Superoxide dismutase activity enabled by a redox-active ligand rather than metal by Ward, Meghan B., Scheitler, Andreas, Yu, Meng, Senft, Laura, Zillmann, Annika S., Gorden, John D., Schwartz, Dean D., Ivanović-Burmazović, Ivana, Goldsmith, Christian R.

“…Reactive oxygen species are integral to many physiological processes. Although their roles are still being elucidated, they seem to be linked to a variety of…”
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Diquinol Functionality Boosts the Superoxide Dismutase Mimicry of a Zn(II) Complex with a Redox-Active Ligand while Maintaining Catalyst Stability and Enhanced Activity in Phosphate Solution by Moore, Jamonica L., Oppelt, Julian, Senft, Laura, Franke, Alicja, Scheitler, Andreas, Dukes, Meghan W., Alix, Haley B., Saunders, Alexander C., Karbalaei, Sana, Schwartz, Dean D., Ivanović-Burmazović, Ivana, Goldsmith, Christian R.

“…In the current work, we demonstrate ligand design concepts that significantly improve the superoxide dismutase (SOD) activity of a zinc complex; the catalysis…”
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A Mononuclear Manganese(II) Complex Demonstrates a Strategy To Simultaneously Image and Treat Oxidative Stress by Yu, Meng, Ambrose, Stephen L, Whaley, Zachary L, Fan, Sanjun, Gorden, John D, Beyers, Ronald J, Schwartz, Dean D, Goldsmith, Christian R

“…A manganese­(II) complex with a ligand containing an oxidizable quinol group serves as a turn-on sensor for H2O2. Upon oxidation, the relaxivity of the complex…”
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Adding a Second Quinol to a Redox-Responsive MRI Contrast Agent Improves Its Relaxivity Response to H2O2 by Yu, Meng, Ward, Meghan B, Franke, Alicja, Ambrose, Stephen L, Whaley, Zachary L, Bradford, Thomas Miller, Gorden, John D, Beyers, Ronald J, Cattley, Russell C, Ivanović-Burmazović, Ivana, Schwartz, Dean D, Goldsmith, Christian R

“…The overproduction of reactive oxygen species has been linked to a wide array of health disorders. The ability to noninvasively monitor oxidative stress in…”
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The Herbicide Atrazine Potentiates Angiotensin II-Induced Aldosterone Synthesis and Release From Adrenal Cells by Zimmerman, Arthur D, Mackay, Laci, Kemppainen, Robert J, Jones, Melaney A, Read, Casey C, Schwartz, Dean, Foradori, Chad D

“…Atrazine is one of the most commonly used pre-emergence and early post-emergence herbicides in the world. We have shown previously that atrazine does not…”
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Adding a Second Quinol to a Redox-Responsive MRI Contrast Agent Improves Its Relaxivity Response to H 2 O 2 by Yu, Meng, Ward, Meghan B, Franke, Alicja, Ambrose, Stephen L, Whaley, Zachary L, Bradford, Thomas Miller, Gorden, John D, Beyers, Ronald J, Cattley, Russell C, Ivanović-Burmazović, Ivana, Schwartz, Dean D, Goldsmith, Christian R

“…The overproduction of reactive oxygen species has been linked to a wide array of health disorders. The ability to noninvasively monitor oxidative stress in…”
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Correction to “A Mononuclear Manganese(II) Complex Demonstrates a Strategy To Simultaneously Image and Treat Oxidative Stress” by Yu, Meng, Ambrose, Stephen L, Whaley, Zachary L, Fan, Sanjun, Gorden, John D, Beyers, Ronald J, Schwartz, Dean D, Goldsmith, Christian R

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Characterization of endothelial colony-forming cells from peripheral blood samples of adult horses by Salter, Margaret M, Seeto, Wen J, DeWitt, Blake B, Hashimi, Sarah A, Schwartz, Dean D, Lipke, Elizabeth A, Wooldridge, Anne A

“…To isolate and characterize endothelial colony-forming cells (ECFCs; a subtype of endothelial progenitor cells) from peripheral blood samples of horses…”
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Heat-induced inhibition of superoxide dismutase and accumulation of reactive oxygen species leads to HT-22 neuronal cell death by El-Orabi, Naglaa F., Rogers, Colin B., Gray Edwards, Heather, Schwartz, Dean D.

“…Superoxide dismutase (SOD) is major cytosolic antioxidant enzyme responsible for dismutation of superoxide anion ( O 2 − ). Alterations in SOD expression and…”
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Abnormal coagulation factor VIII transcript in a Tennessee Walking Horse colt with hemophilia A by Norton, Elaine M., Wooldridge, Anne A., Stewart, Allison J., Cusimano, Layla, Schwartz, Dean D., Johnson, Calvin M., Boudreaux, Mary K., Christopherson, Pete W.

“…Hemophilia A is an X‐chromosome‐linked disorder caused by a deficiency in factor VIII (FVIII). Although foals have been diagnosed with hemophilia A based on…”
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Anti-oxidative and DNA protecting effects of flavonoids-rich Scutellaria lateriflora by Lohani, Madhukar, Ahuja, Manuj, Buabeid, Manal A, Dean, Schwartz, Dennis, Shannon, Suppiramaniam, Vishnu, Kemppainen, Barbara, Dhanasekaran, Muralikrishnan

“…Scutellaria lateriflora (American skullcap), a native plant of North America, has been used by Americans and Europeans as a nerve tonic for more than 200…”
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Activation of PPARγ by Rosiglitazone Does Not Negatively Impact Male Sex Steroid Hormones in Diabetic Rats by Plaisance, Eric, Stewart, Laura Ken, Morrison, Edward, Mansour, Mahmoud M., Judd, Robert L., Braden, Tim D., Schwartz, Dean D., Coleman, Elaine S., Dennis, John, Akingbemi, Benson

“…Peroxisome proliferator-activated receptor gamma (PPARγ) activation decreased serum testosterone (T) in women with hyperthecosis and/or polycystic ovary…”
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Regulation of adiponectin secretion by endothelin-1 by Clarke, Kristen J, Zhong, Qiao, Schwartz, Dean D, Coleman, Elaine S, Kemppainen, Robert J, Judd, Robert L

“…Adiponectin is an adipocyte-derived hormone best known for its insulin-sensitizing ability. The expression and circulating concentration of adiponectin are…”
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Molecular and functional characterization of bovine β-defensin-1 by Aono, Shelly, Li, Changqing, Zhang, Guolong, Kemppainen, Robert J., Gard, Julie, Lu, Wuyuan, Hu, Xueyou, Schwartz, Dean D., Morrison, Edward E., Dykstra, Christine, Shi, Jishu

“…We report the biochemical and functional properties of a novel bovine β-defensin (bBD-1). Cloned from bovine mammary papillary duct epithelia, the bBD-1 cDNA…”
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Endothelin-1 inhibits resistin secretion in 3T3-L1 adipocytes by Zhong, Qiao, Lin, Chia-Yu, Clarke, Kristen J, Kemppainen, Robert J, Schwartz, Dean D, Judd, Robert L

“…Resistin is an adipocyte-derived hormone whose role in the development of insulin resistance is controversial. Endothelin-1 (ET-1) is a 21 amino acid peptide…”
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Effect of myocardial volume overload and heart failure on lactate transport into isolated cardiac myocytes by Evans, Ronald K, Schwartz, Dean D, Gladden, L. Bruce

“…1  School of Human Performance and Recreation, The University of Southern Mississippi, Hattiesburg, Mississippi 39406; and 2  Departments of Anatomy,…”
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Hypotonic swelling stimulates L-type Ca2+ channel activity in vascular smooth muscle cells through PKC by Ding, Yanfeng, Schwartz, Dean, Posner, Philip, Zhong, Juming

“…It has been suggested that L-type Ca(2+) channels play an important role in cell swelling-induced vasoconstriction. However, there is no direct evidence that…”
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Activation of Penile Proadipogenic Peroxisome Proliferator-Activated Receptor γ with an Estrogen: Interaction with Estrogen Receptor Alpha during Postnatal Development by Morrison, Edward E., Coleman, Elaine S., Judd, Robert L., Schwartz, Dean D., Dennis, John C., Braden, Tim D., Goyal, Hari O., Mansour, Mahmoud M., Bartol, Frank F.

“…Exposure to the estrogen receptor alpha (ERα) ligand diethylstilbesterol (DES) between neonatal days 2 to 12 induces penile adipogenesis and adult infertility…”
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Activation of Penile Proadipogenic Peroxisome Proliferator-Activated Receptor with an Estrogen: Interaction with Estrogen Receptor Alpha during Postnatal Development by Mansour, Mahmoud M., Goyal, Hari O., Braden, Tim D., Dennis, John C., Schwartz, Dean D., Judd, Robert L., Bartol, Frank F., Coleman, Elaine S., Morrison, Edward E.

“…Exposure to the estrogen receptor alpha (ER) ligand diethylstilbesterol (DES) between neonatal days 2 to 12 induces penile adipogenesis and adult infertility…”
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