Search Results - "Schwartz, David A"
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Potential Maternal and Infant Outcomes from (Wuhan) Coronavirus 2019-nCoV Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections
Published in Viruses (10-02-2020)“…In early December 2019 a cluster of cases of pneumonia of unknown cause was identified in Wuhan, a city of 11 million persons in the People's Republic of…”
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Placental Pathology of COVID-19 with and without Fetal and Neonatal Infection: Trophoblast Necrosis and Chronic Histiocytic Intervillositis as Risk Factors for Transplacental Transmission of SARS-CoV-2
Published in Viruses (15-11-2020)“…The mechanism(s) by which neonates testing positive for coronavirus disease 2019 (COVID-19) acquire their infection has been largely unknown. Transmission of…”
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Stillbirth after COVID-19 in Unvaccinated Mothers Can Result from SARS-CoV-2 Placentitis, Placental Insufficiency, and Hypoxic Ischemic Fetal Demise, Not Direct Fetal Infection: Potential Role of Maternal Vaccination in Pregnancy
Published in Viruses (23-02-2022)“…Stillbirth is a recently recognized complication of COVID-19 in pregnant women. Other congenitally transmitted infections from viruses, bacteria and parasites…”
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High Rates of Miscarriage and Stillbirth among Pregnant Women with Clade I Mpox (Monkeypox) Are Confirmed during 2023-2024 DR Congo Outbreak in South Kivu Province
Published in Viruses (01-07-2024)“…Mpox (monkeypox) is a neglected tropical disease that has received increased attention since the multi-nation outbreak that began in 2022. The virus is endemic…”
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From ARDS to pulmonary fibrosis: the next phase of the COVID-19 pandemic?
Published in Translational research : the journal of laboratory and clinical medicine (01-03-2022)“…While the coronavirus disease 19 (COVID-19) pandemic has transformed the medical and scientific communites since it was first reported in late 2019, we are…”
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Epigenetics of idiopathic pulmonary fibrosis
Published in Translational research : the journal of laboratory and clinical medicine (01-01-2015)“…Idiopathic pulmonary fibrosis (IPF) is a complex lung disease of unknown etiology. Development of IPF is influenced by both genetic and environmental factors…”
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Being Pregnant during the Kivu Ebola Virus Outbreak in DR Congo: The rVSV-ZEBOV Vaccine and Its Accessibility by Mothers and Infants during Humanitarian Crises and in Conflict Areas
Published in Vaccines (Basel) (22-01-2020)“…The Ebola virus disease (EVD) outbreak that began in Kivu province of the Democratic Republic of the Congo (DRC) in July 2018 is the second largest in history…”
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Revealing the Secrets of Idiopathic Pulmonary Fibrosis
Published in The New England journal of medicine (03-01-2019)“…Pathogenic findings in a mouse model of idiopathic pulmonary fibrosis confirm the pivotal role played by dysfunction of the type 2 alveolar (AT2) epithelial…”
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Molecular Mechanisms in Progressive Idiopathic Pulmonary Fibrosis
Published in Annual review of medicine (14-01-2013)“…There is clear evidence that environmental exposures and genetic predisposition contribute to the pathogenesis of idiopathic pulmonary fibrosis (IPF)…”
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An Analysis of 38 Pregnant Women With COVID-19, Their Newborn Infants, and Maternal-Fetal Transmission of SARS-CoV-2: Maternal Coronavirus Infections and Pregnancy Outcomes
Published in Archives of pathology & laboratory medicine (1976) (01-07-2020)“…The emergence of a novel coronavirus, termed SARS-CoV-2, and the potentially life-threatening respiratory disease that it can produce, COVID-19, has rapidly…”
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Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice
Published in Nature communications (18-12-2018)“…The gain-of-function MUC5B promoter variant rs35705950 is the dominant risk factor for developing idiopathic pulmonary fibrosis (IPF). Here we show in humans…”
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The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium
Published in PloS one (20-03-2013)“…We previously identified a MUC5B gene promoter-variant that is a risk allele for sporadic and familial Idiopathic Pulmonary Fibrosis/Usual Interstitial…”
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Development and Progression of Interstitial Lung Abnormalities in the Framingham Heart Study
Published in American journal of respiratory and critical care medicine (15-12-2016)“…The relationship between the development and/or progression of interstitial lung abnormalities (ILA) and clinical outcomes has not been previously…”
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The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis
Published in American journal of respiratory and critical care medicine (15-10-2014)“…Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease of unknown cause that leads to respiratory failure and death within 5 years of diagnosis…”
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Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional
Published in Nature communications (27-07-2021)“…The airway epithelium serves as the interface between the host and external environment. In many chronic lung diseases, the airway is the site of substantial…”
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Mpox (Monkeypox) in Pregnancy: Viral Clade Differences and Their Associations with Varying Obstetrical and Fetal Outcomes
Published in Viruses (28-07-2023)“…In African countries where mpox (monkeypox) is endemic, infection is caused by two genetically related clades-Clade I (formerly Congo Basin), and Clade IIa…”
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Congenital Mpox Syndrome (Clade I) in Stillborn Fetus after Placental Infection and Intrauterine Transmission, Democratic Republic of the Congo, 2008
Published in Emerging infectious diseases (01-11-2023)“…We report the autopsy pathology findings of a 21-week stillborn fetus with congenital mpox syndrome that occurred in the Democratic Republic of the Congo in…”
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Oropouche Virus (OROV) in Pregnancy: An Emerging Cause of Placental and Fetal Infection Associated with Stillbirth and Microcephaly following Vertical Transmission
Published in Viruses (09-09-2024)“…Oropouche virus (OROV) is an emerging arbovirus endemic in Latin America and the Caribbean that causes Oropouche fever, a febrile illness that clinically…”
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Epigenetic mechanisms and the development of asthma
Published in Journal of allergy and clinical immunology (01-12-2012)“…Asthma is heritable, influenced by the environment, and modified by in utero exposures and aging; all of these features are also common to epigenetic…”
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CT Scan Findings of Probable Usual Interstitial Pneumonitis Have a High Predictive Value for Histologic Usual Interstitial Pneumonitis
Published in Chest (01-02-2015)“…The current usual interstitial pneumonitis (UIP)/idiopathic pulmonary fibrosis CT scan classification system excludes probable UIP as a diagnostic category. We…”
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