Search Results - "Schwartz, A"

Potential Maternal and Infant Outcomes from (Wuhan) Coronavirus 2019-nCoV Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections by Schwartz, David A, Graham, Ashley L

“…In early December 2019 a cluster of cases of pneumonia of unknown cause was identified in Wuhan, a city of 11 million persons in the People's Republic of…”
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Fluid Shear Stress on Endothelial Cells Modulates Mechanical Tension across VE-Cadherin and PECAM-1 by Conway, Daniel E., Breckenridge, Mark T., Hinde, Elizabeth, Gratton, Enrico, Chen, Christopher S., Schwartz, Martin A.

“…Fluid shear stress (FSS) from blood flow acting on the endothelium critically regulates vascular morphogenesis, blood pressure, and atherosclerosis [1]. FSS…”
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Placental Pathology of COVID-19 with and without Fetal and Neonatal Infection: Trophoblast Necrosis and Chronic Histiocytic Intervillositis as Risk Factors for Transplacental Transmission of SARS-CoV-2 by Schwartz, David A, Morotti, Denise

“…The mechanism(s) by which neonates testing positive for coronavirus disease 2019 (COVID-19) acquire their infection has been largely unknown. Transmission of…”
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Vascular Mechanobiology: Homeostasis, Adaptation, and Disease by Humphrey, Jay D, Schwartz, Martin A

“…Cells of the vascular wall are exquisitely sensitive to changes in their mechanical environment. In healthy vessels, mechanical forces regulate signaling and…”
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Mechanotransduction in vascular physiology and atherogenesis by Schwartz, Martin A, Hahn, Cornelia

“…Key Points Fluid shear stress from blood flow and circumferential stretch of vessel walls from blood pressure are important regulatory factors that control the…”
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Talin as a mechanosensitive signaling hub by Goult, Benjamin T, Yan, Jie, Schwartz, Martin A

“…Cell adhesion to the extracellular matrix (ECM), mediated by transmembrane receptors of the integrin family, is exquisitely sensitive to biochemical,…”
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Biomechanics of vascular mechanosensation and remodeling by Baeyens, Nicolas, Schwartz, Martin A

“…Flowing blood exerts a frictional force, fluid shear stress (FSS), on the endothelial cells that line the blood and lymphatic vessels. The magnitude,…”
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Mechanotransduction and extracellular matrix homeostasis by Humphrey, Jay D., Dufresne, Eric R., Schwartz, Martin A.

“…Key Points Under steady state conditions, cells must actively maintain the mechanical properties of the extracellular matrix (ECM) to maintain the normal…”
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Acute generalized exanthematous pustulosis (AGEP): A review and update by Szatkowski, Jesse, MD, Schwartz, Robert A., MD, MPH, DSc (Hon), FRCP (Edin)

“…Acute generalized exanthematous pustulosis is a severe cutaneous adverse reaction characterized by the rapid development of nonfollicular, sterile pustules on…”
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Stillbirth after COVID-19 in Unvaccinated Mothers Can Result from SARS-CoV-2 Placentitis, Placental Insufficiency, and Hypoxic Ischemic Fetal Demise, Not Direct Fetal Infection: Potential Role of Maternal Vaccination in Pregnancy by Schwartz, David A

“…Stillbirth is a recently recognized complication of COVID-19 in pregnant women. Other congenitally transmitted infections from viruses, bacteria and parasites…”
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Endothelial fluid shear stress sensing in vascular health and disease by Baeyens, Nicolas, Bandyopadhyay, Chirosree, Coon, Brian G, Yun, Sanguk, Schwartz, Martin A

“…Endothelial cells transduce the frictional force from blood flow (fluid shear stress) into biochemical signals that regulate gene expression and cell behavior…”
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High Rates of Miscarriage and Stillbirth among Pregnant Women with Clade I Mpox (Monkeypox) Are Confirmed during 2023-2024 DR Congo Outbreak in South Kivu Province by Schwartz, David A

“…Mpox (monkeypox) is a neglected tropical disease that has received increased attention since the multi-nation outbreak that began in 2022. The virus is endemic…”
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From ARDS to pulmonary fibrosis: the next phase of the COVID-19 pandemic? by Michalski, Jacob E., Kurche, Jonathan S., Schwartz, David A.

“…While the coronavirus disease 19 (COVID-19) pandemic has transformed the medical and scientific communites since it was first reported in late 2019, we are…”
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Microbial Biofilm: A Review on Formation, Infection, Antibiotic Resistance, Control Measures, and Innovative Treatment by Sharma, Satish, Mohler, James, Mahajan, Supriya D, Schwartz, Stanley A, Bruggemann, Liana, Aalinkeel, Ravikumar

“…Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide matrix that attaches to foreign surfaces in a living organism…”
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Endothelial-to-mesenchymal transition drives atherosclerosis progression by Chen, Pei-Yu, Qin, Lingfeng, Baeyens, Nicolas, Li, Guangxin, Afolabi, Titilayo, Budatha, Madhusudhan, Tellides, George, Schwartz, Martin A, Simons, Michael

“…The molecular mechanisms responsible for the development and progression of atherosclerotic lesions have not been fully established. Here, we investigated the…”
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Gold nanoshell-localized photothermal ablation of prostate tumors in a clinical pilot device study by Rastinehad, Ardeshir R., Anastos, Harry, Wajswol, Ethan, Winoker, Jared S., Sfakianos, John P., Doppalapudi, Sai K., Carrick, Michael R., Knauer, Cynthia J., Taouli, Bachir, Lewis, Sara C., Tewari, Ashutosh K., Schwartz, Jon A., Canfield, Steven E., George, Arvin K., West, Jennifer L., Halas, Naomi J.

“…Biocompatible gold nanoparticles designed to absorb light at wave-lengths of high tissue transparency have been of particular interest for biomedical…”
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ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation by Tornavaca, Olga, Chia, Minghao, Dufton, Neil, Almagro, Lourdes Osuna, Conway, Daniel E, Randi, Anna M, Schwartz, Martin A, Matter, Karl, Balda, Maria S

“…Intercellular junctions are crucial for mechanotransduction, but whether tight junctions contribute to the regulation of cell-cell tension and adherens…”
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Keratoacanthoma (KA): An update and review by Kwiek, Bartlomiej, MD, PhD, Schwartz, Robert A., MD, MPH

“…Keratoacanthoma (KA) is a common but underreported tumor of the skin. Two striking features of KA are its clinical behavior with spontaneous regression after…”
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Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification by Fang, Jennifer S., Coon, Brian G., Gillis, Noelle, Chen, Zehua, Qiu, Jingyao, Chittenden, Thomas W., Burt, Janis M., Schwartz, Martin A., Hirschi, Karen K.

“…Establishment of a functional vascular network is rate-limiting in embryonic development, tissue repair and engineering. During blood vessel formation, newly…”
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Translocating transcription factors in fluid shear stress-mediated vascular remodeling and disease by Min, Elizabeth, Schwartz, Martin A.

“…Endothelial cells are exposed to fluid shear stress profiles that vary in magnitude, pulsatility, and directionality due to regional variations in blood vessel…”
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