Search Results - "Schwarm, Michael"

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    Biocatalysis to amino acid-based chiral pharmaceuticals—examples and perspectives by Bommarius, Andreas S., Schwarm, Michael, Drauz, Karlheinz

    “…The search for and development of new pharmaceutically active structures drives the need for new enantiomerically pure compounds (EPC). Many N-containing…”
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    Journal Article Conference Proceeding
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    Comparison of Different Chemoenzymatic Process Routes to Enantiomerically Pure Amino Acids by Andreas S. Bommarius, Michael Schwarm, Karlheinz Drauz

    Published in Chimia (01-01-2001)
    “…Five common biocatalytic process platforms for the production of enantiomerically pure amino acids are compared along four different dimensions of merit: i)…”
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    Journal Article
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    In vitro dissolution behaviour and absorption in humans of a novel mixed l-lysine salt formulation of EPA and DHA by Manusama, Koen, Balvers, Michiel, Diepeveen-de Bruin, Marlies, Headley, Laura, Bosi, Roberta, Schwarm, Michael, Witkamp, Renger

    “…A l-lysine salt of EPA and DHA offers favourable stability and technical properties.The formulation showed complete in vitro dissolution under simulated GI…”
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    Journal Article
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    Synthesis and use of enantiomerically pure tert-leucine by Bommarius, Andreas S., Schwarm, Michael, Stingl, Klaus, Kottenhahn, Matthias, Huthmacher, Klaus, Drauz, Karlheinz

    Published in Tetrahedron: asymmetry (01-12-1995)
    “…Owing to its bulky, inflexible and hydrophobic tert-butyl side chain, tert-leucine (Tle) finds increased use in templates or catalysts in asymmetric synthesis…”
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    Journal Article
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    Enantiopure β 3-neopentylglycine: synthesis and resolution by ter Wiel, Matthijs K.J., Arnold, Mirjam, Peter, Sandra, Troltsch, Ingo, Merget, Stefan, Glaser, Florian, Schwarm, Michael, Bhatti, Harjinder S., Kuriakose, Biju, Pol, Suryakant S., Balamurugan, Mohanasundaram, Joshi, Viral V.

    Published in Tetrahedron: asymmetry (2009)
    “…A procedure has been developed for the large scale synthesis of enantiopure β 3-neopentylglycine and its Cbz-protected derivative. The synthetic route…”
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    Journal Article
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    Comparison of Different Chemoenzymatic Process Routes to Enantiomerically Pure Amino Acids by Andreas S. Bommarius, Michael Schwarm, Karlheinz Drauz

    Published in Chimia (01-01-2001)
    “…Five common biocatalytic process platforms for the production of enantiomerically pure amino acids are compared along four different dimensions of merit: i)…”
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    Journal Article
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    l-methionine related l-amino acids by acylase cleavage of their corresponding [formula omitted] by Bommarius, Andreas S., Drauz, Karlheinz, Günther, Kurt, Knaup, Günter, Schwarm, Michael

    Published in Tetrahedron: asymmetry (01-10-1997)
    “…Acylase I from Aspergillus oryzae is an even more useful enzyme than suggested so far. Besides standard amino acids such as l-Met, l-Val and l-Phe, a number of…”
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    Journal Article
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