Search Results - "Schwarer, A P"

Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR by Ross, D M, Branford, S, Seymour, J F, Schwarer, A P, Arthur, C, Bartley, P A, Slader, C, Field, C, Dang, P, Filshie, R J, Mills, A K, Grigg, A P, Melo, J V, Hughes, T P

“…Around 40–50% of patients with chronic myeloid leukemia (CML) who achieve a stable complete molecular response (CMR; undetectable breakpoint cluster…”
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Sustained deep molecular responses in patients switched to nilotinib due to persistent BCR-ABL1 on imatinib: final ENESTcmr randomized trial results by Hughes, T P, Leber, B, Cervantes, F, Spector, N, Pasquini, R, Clementino, N C D, Schwarer, A P, Dorlhiac-Llacer, P E, Mahon, F-X, Rea, D, Guerci-Bresler, A, Kamel-Reid, S, Bendit, I, Acharya, S, Glynos, T, Dalal, D, Branford, S, Lipton, J H

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A Randomized, Open-Label, Multicenter Comparative Study of the Efficacy and Safety of Piperacillin-Tazobactam and Cefepime for the Empirical Treatment of Febrile Neutropenic Episodes in Patients with Hematologic Malignancies by Bow, E. J., Rotstein, C., Noskin, G. A., re, M. Laverdiè, Schwarer, A. P., Segal, B. H., Seymour, J. F., Szer, J., Sanche, S.

“…Background. The empirical treatment of febrile, neutropenic patients with cancer requires antibacterial regimens active against both gram-positive and…”
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Respiratory virus infections after stem cell transplantation: a prospective study from the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation by LJUNGMAN, P, WARD, K. N, PAUKSEN, K, RUSSELL, N, SCHWARER, A. P, CORDONNIER, C, CROOKS, B. N. A, PARKER, A, MARTINO, R, SHAW, P. J, BRINCH, L, BRUNE, M, DE LA CAMARA, R, DEKKER, A

“…Community-acquired respiratory virus infections are a cause of mortality after stem cell transplantation (SCT). A prospective study was performed at 37 centers…”
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Imatinib produces significantly superior molecular responses compared to interferon alfa plus cytarabine in patients with newly diagnosed chronic myeloid leukemia in chronic phase by BRANFORD, S, RUDZKI, Z, SEYMOUR, J. F, BRADSTOCK, K, JOSKE, D, LYNCH, K, GATHMANN, I, HUGHES, T. P, HARPER, A, GRIGG, A, TAYLOR, K, DURRANT, S, ARTHUR, C, BROWETT, P, SCHWARER, A. P, MA, D

“…We analyzed molecular responses in 55 newly diagnosed chronic-phase chronic myeloid leukemia (CML) patients enrolled in a phase 3 study (the IRIS trial)…”
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Successful control of Disseminated Scedosporium prolificans infection with a combination of voriconazole and terbinafine by HOWDEN, B. P, SLAVIN, M. A, SCHWARER, A. P, MIJCH, A. M

“…Disseminated Scedosporium prolificans infections are almost uniformly fatal because of their resistance to antifungal agents. Recently, synergy between…”
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Pamidronate Reduces Bone Loss after Allogeneic Stem Cell Transplantation by Grigg, A. P., Shuttleworth, P., Reynolds, J., Schwarer, A. P., Szer, J., Bradstock, K., Hui, C., Herrmann, R., Ebeling, P. R.

“…Background: Rapid bone loss occurs from the proximal femur after allogeneic stem cell transplantation (alloSCT). Objective: The objective of the study was to…”
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Long-term follow-up of a pilot study using a chemotherapy-alone protocol for killer Ig-like receptor-ligand-mismatched haploidentical haematopoietic SCT by Schwarer, A P, Bollard, G, Kapuscinski, M, Muirhead, J, Diviney, M, Hart, C, Dunster, K

“…Advanced haematological malignancies are incurable without allogeneic haematopoietic SCT (HSCT). Many patients do not have a human leukocyte Ag (HLA)-matched…”
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A randomized comparison of empiric or pre-emptive antibiotic therapy after hematopoietic stem cell transplantation by SLAVIN, M. A, GRIGG, A. P, SCHWARER, A. P, SZER, J, SPENCER, A, SAINANI, A, THURSKY, K. A, ROBERTS, A. W

“…We performed a randomized comparison of pre-emptive and empiric antibiotic therapy for adult patients undergoing allogeneic or autologous stem cell…”
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Abnormal cervical cytology in bone marrow transplant recipients by SASADEUSZ, J, KELLY, H, SZER, J, SCHWARER, A. P, MITCHELL, H, GRIGG, A

“…Particular human papillomavirus (HPV) subtypes are implicated in the genesis of abnormal cervical cytology and cervical cancer. While most immunocompetent…”
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Successful mobilization of peripheral blood stem cells using recombinant human stem cell factor in heavily pretreated patients who have failed a previous attempt with a granulocyte colony-stimulating factor-based regimen by DAWSON, M. A, SCHWARER, A. P, MUIRHEAD, J. L, BAILEY, M. J, BOLLARD, G. M, SPENCER, A

“…To assess the efficacy of recombinant human stem cell factor (rHuSCF), 48 patients who had failed to mobilize >2.0 x 10(6) CD34+ cells/kg with granulocyte…”
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Successful mobilization of peripheral blood stem cells after addition of ancestim (stem cell factor) in patients who had failed a prior mobilization with filgrastim (granulocyte colony-stimulating factor) alone or with chemotherapy plus filgrastim by TO, L. B, BASHFORD, J, RAWLING, T, ASHMAN, L, CHARLES, S, COHEN, B, DURRANT, S, MACMILLAN, J, SCHWARER, A. P, PRINCE, H. M, GIBSON, J, LEWIS, I, SWART, B, MARTY, J

“…This study assessed the ability of recombinant human stem cell factor (rHuSCF) to mobilize stem cells in 44 patients who had failed a prior mobilization…”
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Intermediate-dose CY and G-CSF more efficiently mobilize adequate numbers of PBSC for tandem autologous PBSC transplantation compared with low-dose CY in patients with multiple myeloma by Hiwase, D.K, Bollard, G, Hiwase, S, Bailey, M, Muirhead, J, Schwarer, A.P

“…Background Autologous PBSC transplantation is the standard care for patients with multiple myeloma. The most common regimen used to mobilize PBSC consists of…”
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The helper T lymphocyte precursor (HTLp) frequency does not predict outcome after HLA-identical sibling donor G-CSF-mobilised peripheral blood stem cell transplantation by HEALEY, G, SCHWARER, A. P

“…Here, we report the first study assessing the helper T lymphocyte precursor (HTLp) frequency as a predictor of outcome in patients undergoing allogeneic PBSC…”
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Optimal scheduling to reduce morbidity of involved field radiotherapy with transplantation for lymphomas: A Prospective Australasian Leukaemia and Lymphoma Group Study by WIRTH, A, PRINCE, H. M, ROOS, D, SCHWARER, A. P, DAVIS, S, WOLF, M, STONE, J. M, MATTHEWS, J, GIBSON, J, MACLEOD, C, SZER, J, GRIGG, A, TO, B

“…This study evaluated delivery of involved field radiotherapy (IFRT) with transplantation for lymphomas timed to minimise toxicity. Patients transplanted for…”
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Improved detection of clinically significant host-reactive antigens prior to HLA-identical sibling peripheral blood stem cell transplantation using a dendritic cell-based helper T-lymphocyte precursor assay by SCHWARER, A. P, HEALEY, G, HAMMETT, M

“…Graft-versus-host disease (GVHD) due to host-reactive antigenic differences between HLA-identical pairs remains an important cause of morbidity and mortality…”
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Frequency of anti-recipient alloreactive helper T-cell precursors in donor blood and graft-versus-host disease after HLA-identical sibling bone-marrow transplantation by Schwarer, A P, Jiang, Y Z, Brookes, P A, Barrett, A J, Batchelor, J R, Goldman, J M, Lechler, R I

“…A substantial proportion of patients undergoing allogeneic bone-marrow transplantation (BMT) develop moderate-to-severe acute graft-versus-host disease (GVHD)…”
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Cytomegalovirus viral load monitoring after allogeneic bone marrow transplantation in patients receiving antiviral prophylaxis by HOWDEN, B. P, MICHAELIDES, A, SPELMAN, D. W, SPENCER, A, SCHWARER, A. P, WESSELINGH, S, KOTSIMBOS, T. C

“…Cytomegalovirus viral load measurement is a powerful new tool for monitoring of CMV disease; however, the optimal strategy for use is unknown. Weekly plasma…”
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Chemotherapy and granulocyte colony stimulating factor-mobilized blood cell infusion followed by interferon-α for relapsed malignancy after allogeneic bone marrow transplantation by Grigg, A., Kannan, K., Schwarer, A. P., Spencer, A., Szer, J.

“…Background: Interferon‐α (IFN) is known to promote graft‐versus‐host disease (GVHD) after allogeneic bone marrow transplantation (allo BMT). This property may…”
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Intravenous and oral Itraconazole versus Intravenous Amphotericin B deoxycholate as empirical antifungal therapy for persistent fever in neutropenic patients with cancer who are receiving broad-spectrum antibacterial therapy : A randomized, controlled trial by BOOGAERTS, Marc, WINSTON, Drew J, BOW, Eric J, GARBER, Gary, REBOLI, Annette C, SCHWARER, Anthony P, NOVITZKY, Nicolas, BOEHME, Angelika, CHWETZOFF, Elisabeth, DE BEULE, Karel

“…Amphotericin B deoxycholate is currently the standard empirical antifungal therapy in neutropenic patients with cancer who have persistent fever that does not…”
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