Search Results - "Schwalbe, H"
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1
Detection of osteoarthritis using acoustic emission analysis
Published in Medical engineering & physics (01-03-2019)“…•Acoustic emission from patients’ knees tells type and location of cartilage lesions.•AE detects cartilage alterations which are not visible in MRI.•With MRI…”
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2
Metal-ion binding and metal-ion induced folding of the adenine-sensing riboswitch aptamer domain
Published in Nucleic acids research (01-08-2007)“…Divalent cations are important in the folding and stabilization of complex RNA structures. The adenine-sensing riboswitch controls the expression of mRNAs for…”
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3
(19)F-labeling of the adenine H2-site to study large RNAs by NMR spectroscopy
Published in Journal of biomolecular NMR (01-01-2016)“…In comparison to proteins and protein complexes, the size of RNA amenable to NMR studies is limited despite the development of new isotopic labeling strategies…”
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4
Paramagnetic-iterative relaxation matrix approach: extracting PRE-restraints from NOESY spectra for 3D structure elucidation of biomolecules
Published in Journal of biomolecular NMR (01-12-2019)“…Paramagnetic relaxation enhancement (PRE) can be used to determine long-range distance restraints in biomolecules. The PREs are typically determined by…”
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Interplay of 'induced fit' and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch
Published in Nucleic acids research (01-01-2007)“…Riboswitches are highly structured elements in the 5'-untranslated regions (5'-UTRs) of messenger RNA that control gene expression by specifically binding to…”
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6
Impact of spin label rigidity on extent and accuracy of distance information from PRE data
Published in Journal of biomolecular NMR (01-05-2017)“…Paramagnetic relaxation enhancement (PRE) is a versatile tool for NMR spectroscopic structural and kinetic studies in biological macromolecules. Here, we…”
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1H, 13C, and 15N backbone chemical shift assignments of the apo and the ADP-ribose bound forms of the macrodomain of SARS-CoV-2 non-structural protein 3b
Published in Biomolecular NMR assignments (01-10-2020)“…The SARS-CoV-2 genome encodes for approximately 30 proteins. Within the international project COVID19-NMR, we distribute the spectroscopic analysis of the…”
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8
June Sutor and the C-H ··· O hydrogen bonding controversy
Published in Crystallography reviews (01-07-2012)“…In 1962, D. June Sutor published the first crystallographic analysis of C-H ··· O hydrogen bonding based on a selection of structures then known. Her follow-up…”
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1H, 13C, and 15N backbone chemical shift assignments of coronavirus-2 non-structural protein Nsp10
Published in Biomolecular NMR assignments (01-04-2021)“…The international Covid19-NMR consortium aims at the comprehensive spectroscopic characterization of SARS-CoV-2 RNA elements and proteins and will provide NMR…”
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10
Analgesic Effects of 5-Alkyloxy-4-amino-2(5H)-furanones as Cholecystokinin-2 Antagonists
Published in Archiv der Pharmazie (Weinheim) (01-06-2016)“…4‐Amino‐2(5H)‐furanones were synthesized in high yields over two synthetic steps from readily available mucochloric acid. These…”
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Quinols as Novel Therapeutic Agents. 2. 4-(1-Arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and Related Agents as Potent and Selective Antitumor Agents
Published in Journal of medicinal chemistry (27-01-2005)“…A series of substituted 4-(1-arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones (indolylquinols) has been synthesized on the basis of the discovery of…”
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12
Fracture in lamellar TiAl simulated with the cohesive model
Published in Engineering fracture mechanics (01-11-2007)“…Fracture behaviour of lamellar TiAl is studied by means of experiments and numerical simulations using a cohesive model. The fracture process can be described…”
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13
Should we remediate small molecule structures? If so, who should do it?
Published in Crystallography reviews (02-10-2018)“…Problems can arise in crystallographic databases with errors and omissions in the representation of data that impede searches, and with errors in the actual…”
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14
Binding of Ca2+ to glutamic acid-rich polypeptides from the rod outer segment
Published in Biophysical journal (01-05-2007)“…Rod photoreceptors contain three different glutamic acid-rich proteins (GARPs) that have been proposed to control the propagation of Ca(2+) from the site of…”
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15
Emergency medicine in the German Maritime Search and Rescue Service-Evaluation of medical emergencies in the North Sea and Baltic Sea over 2 years
Published in Der Anaesthesist (01-04-2021)“…The logistic peculiarities of an emergency maritime location and the frequent additional threat of accidental hypothermia mean that the treatment of medical…”
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16
Basic principles of analytical flaw assessment methods
Published in The International journal of pressure vessels and piping (01-12-2000)“…Analytical flaw assessment methods play an important role in the industrial realisation of fracture mechanics application. In the field of general as well as…”
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17
Boron-Based Inhibitors of the NLRP3 Inflammasome
Published in Cell chemical biology (16-11-2017)“…NLRP3 is a receptor important for host responses to infection, yet is also known to contribute to devastating diseases such as Alzheimer's disease, diabetes,…”
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More than a decade in the making: A study of the implementation of India's Right to Information Act
Published in World development (01-12-2020)“…•Technocratic factors embedded in the Indian Right-to-Information Act may be insufficient for bureaucratic change.•Right-to-Information coalitions can drive a…”
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Solution NMR Spectroscopy of [α-15N]Lysine-Labeled Rhodopsin: The Single Peak Observed in Both Conventional and TROSY-Type HSQC Spectra is Ascribed to Lys-339 in the Carboxyl-Terminal Peptide Sequence
Published in Proceedings of the National Academy of Sciences - PNAS (19-03-2002)“…[α-15N]Lysine-labeled rhodopsin, prepared by expression of a synthetic gene in HEK293 cells, was investigated both by conventional and transverse relaxation…”
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20
Application of the cohesive model for predicting the residual strength of a large scale fuselage structure with a two-bay crack
Published in Engineering failure analysis (01-12-2009)“…The residual strength of a curved and stiffened panel containing a two-bay crack was assessed using the cohesive model. This panel represents a section of a…”
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