Search Results - "Schwager, Emma"

Multivariable association discovery in population-scale meta-omics studies by Mallick, Himel, Rahnavard, Ali, McIver, Lauren J, Ma, Siyuan, Zhang, Yancong, Nguyen, Long H, Tickle, Timothy L, Weingart, George, Ren, Boyu, Schwager, Emma H, Chatterjee, Suvo, Thompson, Kelsey N, Wilkinson, Jeremy E, Subramanian, Ayshwarya, Lu, Yiren, Waldron, Levi, Paulson, Joseph N, Franzosa, Eric A, Bravo, Hector Corrada, Huttenhower, Curtis

“…It is challenging to associate features such as human health outcomes, diet, environmental conditions, or other metadata to microbial community measurements,…”
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Assessment of variation in microbial community amplicon sequencing by the Microbiome Quality Control (MBQC) project consortium by Sinha, Rashmi, Abu-Ali, Galeb, Vogtmann, Emily, Fodor, Anthony A, Ren, Boyu, Amir, Amnon, Schwager, Emma, Crabtree, Jonathan, Ma, Siyuan, Abnet, Christian C, Knight, Rob, White, Owen, Huttenhower, Curtis

“…The Microbiome Quality Control project consortium reports outcomes of a baseline study (MBQC) that will guide future improvements in reproducibility of…”
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The Treatment-Naive Microbiome in New-Onset Crohn’s Disease by Gevers, Dirk, Kugathasan, Subra, Denson, Lee A., Vázquez-Baeza, Yoshiki, Van Treuren, Will, Ren, Boyu, Schwager, Emma, Knights, Dan, Song, Se Jin, Yassour, Moran, Morgan, Xochitl C., Kostic, Aleksandar D., Luo, Chengwei, González, Antonio, McDonald, Daniel, Haberman, Yael, Walters, Thomas, Baker, Susan, Rosh, Joel, Stephens, Michael, Heyman, Melvin, Markowitz, James, Baldassano, Robert, Griffiths, Anne, Sylvester, Francisco, Mack, David, Kim, Sandra, Crandall, Wallace, Hyams, Jeffrey, Huttenhower, Curtis, Knight, Rob, Xavier, Ramnik J.

“…Inflammatory bowel diseases (IBDs), including Crohn’s disease (CD), are genetically linked to host pathways that implicate an underlying role for aberrant…”
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A Bayesian method for detecting pairwise associations in compositional data by Schwager, Emma, Mallick, Himel, Ventz, Steffen, Huttenhower, Curtis

“…Compositional data consist of vectors of proportions normalized to a constant sum from a basis of unobserved counts. The sum constraint makes inference on…”
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A statistical model for describing and simulating microbial community profiles by Ma, Siyuan, Ren, Boyu, Mallick, Himel, Moon, Yo Sup, Schwager, Emma, Maharjan, Sagun, Tickle, Timothy L, Lu, Yiren, Carmody, Rachel N, Franzosa, Eric A, Janson, Lucas, Huttenhower, Curtis

“…Many methods have been developed for statistical analysis of microbial community profiles, but due to the complex nature of typical microbiome measurements…”
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Integrative analysis of the microbiome and metabolome of the human intestinal mucosal surface reveals exquisite inter-relationships by McHardy, Ian H, Goudarzi, Maryam, Tong, Maomeng, Ruegger, Paul M, Schwager, Emma, Weger, John R, Graeber, Thomas G, Sonnenburg, Justin L, Horvath, Steve, Huttenhower, Curtis, McGovern, Dermot Pb, Fornace, Jr, Albert J, Borneman, James, Braun, Jonathan

“…Consistent compositional shifts in the gut microbiota are observed in IBD and other chronic intestinal disorders and may contribute to pathogenesis. The…”
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Association of systolic, diastolic, mean, and pulse pressure with morbidity and mortality in septic ICU patients: a nationwide observational study by Khanna, Ashish K., Kinoshita, Takahiro, Natarajan, Annamalai, Schwager, Emma, Linn, Dustin D., Dong, Junzi, Ghosh, Erina, Vicario, Francesco, Maheshwari, Kamal

“…Background Intensivists target different blood pressure component values to manage intensive care unit (ICU) patients with sepsis. We aimed to evaluate the…”
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Machine learning modelling for predicting the utilization of invasive and non‐invasive ventilation throughout the ICU duration by Schwager, Emma, Nabian, Mohsen, Liu, Xinggang, Feng, Ting, French, Robin, Amelung, Pam, Atallah, Louis, Badawi, Omar

“…The goal of this work is to develop a Machine Learning model to predict the need for both invasive and non‐invasive mechanical ventilation in intensive care…”
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Machine learning prediction of the total duration of invasive and non-invasive ventilation During ICU Stay by Schwager, Emma, Liu, Xinggang, Nabian, Mohsen, Feng, Ting, French, Robin MacDonald, Amelung, Pam, Atallah, Louis, Badawi, Omar

“…Predicting the duration of ventilation in the ICU helps in assessing the risk of ventilator-induced lung injury, ensuring sufficient oxygenation, and…”
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Opioid Administration Practice Patterns in Patients With Acute Respiratory Failure Who Undergo Invasive Mechanical Ventilation by Myers, Laura C, Bosch, Nicholas A, Soltesz, Lauren, Daly, Kathleen A, Campbell, Cynthia I, Schwager, Emma, Salvati, Emmanuele, Stevens, Jennifer P, Wunsch, Hannah, Rucci, Justin M, Jafarzadeh, S Reza, Liu, Vincent X, Walkey, Allan J

“…The opioid crisis is impacting people across the country and deserves attention to be able to curb the rise in opioid-related deaths. To evaluate practice…”
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Fluoride Depletes Acidogenic Taxa in Oral but Not Gut Microbial Communities in Mice by Yasuda, Koji, Hsu, Tiffany, Gallini, Carey A, Mclver, Lauren J, Schwager, Emma, Shi, Andy, DuLong, Casey R, Schwager, Randall N, Abu-Ali, Galeb S, Franzosa, Eric A, Garrett, Wendy S, Huttenhower, Curtis, Morgan, Xochitl C

“…Fluoridation of drinking water and dental products prevents dental caries primarily by inhibiting energy harvest in oral cariogenic bacteria (such as and ),…”
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1078: Predicting Invasive and Noninvasive Ventilation During an ICU Stay by Schwager, Emma, Liu, Xinggang, French, Robin, Amelung, Pam, Badawi, Omar

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Accurate and interpretable prediction of ICU-acquired AKI by Schwager, Emma, Ghosh, Erina, Eshelman, Larry, Pasupathy, Kalyan S., Barreto, Erin F., Kashani, Kianoush

“…We developed and validated two parsimonious algorithms to predict the time of diagnosis of any stage of acute kidney injury (any-AKI) or moderate-to-severe AKI…”
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Reprograming of gut microbiome energy metabolism by the FUT2 Crohn’s disease risk polymorphism by Tong, Maomeng, McHardy, Ian, Ruegger, Paul, Goudarzi, Maryam, Kashyap, Purna C, Haritunians, Talin, Li, Xiaoxiao, Graeber, Thomas G, Schwager, Emma, Huttenhower, Curtis, Fornace, Albert J, Sonnenburg, Justin L, McGovern, Dermot PB, Borneman, James, Braun, Jonathan

“…Fucosyltransferase 2 ( FUT2 ) is an enzyme that is responsible for the synthesis of the H antigen in body fluids and on the intestinal mucosa. The H antigen is…”
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High-sensitivity pattern discovery in large, paired multiomic datasets by Ghazi, Andrew R, Sucipto, Kathleen, Rahnavard, Ali, Franzosa, Eric A, McIver, Lauren J, Lloyd-Price, Jason, Schwager, Emma, Weingart, George, Moon, Yo Sup, Morgan, Xochitl C, Waldron, Levi, Huttenhower, Curtis

“…Abstract Motivation Modern biological screens yield enormous numbers of measurements, and identifying and interpreting statistically significant associations…”
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Predicting acute kidney injury in critically ill patients using comorbid conditions utilizing machine learning by Shawwa, Khaled, Ghosh, Erina, Lanius, Stephanie, Schwager, Emma, Eshelman, Larry, Kashani, Kianoush B

“…Acute kidney injury (AKI) carries a poor prognosis. Its incidence is increasing in the intensive care unit (ICU). Our purpose in this study is to develop and…”
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Estimation of Baseline Serum Creatinine with Machine Learning by Ghosh, Erina, Eshelman, Larry, Lanius, Stephanie, Schwager, Emma, Pasupathy, Kalyan S, Barreto, Erin F, Kashani, Kianoush

“…Comparing current to baseline serum creatinine is important in detecting acute kidney injury. In this study, we report a regression-based machine learning…”
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Including urinary output to define AKI enhances the performance of machine learning models to predict AKI at admission by Schwager, Emma, Lanius, Stephanie, Ghosh, Erina, Eshelman, Larry, Pasupathy, Kalyan S., Barreto, Erin F., Kashani, Kianoush

“…Acute kidney injury (AKI) is a prevalent and detrimental condition in intensive care unit patients. Most AKI predictive models only predict…”
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Statistical Methods for Sequence-Based Microbial Community Assays by Schwager, Emma Holdrich

“…The human microbiome comprises the totality of micro-organisms residing in and on the human body. Of late, it has been the subject of much intensive research…”
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Sa1800 The Crohn's Disease Risk Locus FUT2 Selects for Microbial Functional Specialization in Normal Individuals That Predisposes to IBD Susceptibility by Tong, Maomeng, McHardy, Ian, Ruegger, Paul, Schwager, Emma, Fleshner, Phillip, Li, XiaoXiao, McGovern, Dermot P, Huttenhower, Curtis, Borneman, James, Braun, Jonathan

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