Search Results - "Schwager, Andrea"
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Lesions of the lateral habenula increase voluntary ethanol consumption and operant self-administration, block yohimbine-induced reinstatement of ethanol seeking, and attenuate ethanol-induced conditioned taste aversion
Published in PloS one (01-04-2014)“…The lateral habenula (LHb) plays an important role in learning driven by negative outcomes. Many drugs of abuse, including ethanol, have dose-dependent…”
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Journal Article -
2
Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity
Published in Nature neuroscience (01-08-2014)“…Exposure to psychostimulants such as cocaine induces synaptic plasticity within the nucleus accumbens (NAc) and alters behavior. Here the authors find a new…”
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3
Impaired flexibility in decision making in rats after administration of the pharmacological stressor yohimbine
Published in Psychopharmacology (01-10-2014)“…Rationale Stress-induced disruption of decision making has been hypothesized to contribute to drug-seeking behaviors and addiction. Noradrenergic signaling…”
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4
OKN-007 decreases tumor necrosis and tumor cell proliferation and increases apoptosis in a preclinical F98 rat glioma model
Published in Journal of magnetic resonance imaging (01-12-2015)“…Background Glioblastoma is a malignant World Health Organization (WHO) grade IV glioma with a poor prognosis in humans. New therapeutics are desperately…”
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Journal Article -
5
Regression of glioma tumor growth in F98 and U87 rat glioma models by the Nitrone OKN-007
Published in Neuro-oncology (Charlottesville, Va.) (01-03-2013)“…Glioblastoma multiforme, a World Health Organization grade IV glioma, has a poor prognosis in humans despite current treatment options. Here, we present…”
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6
Bioimaging of copper alterations in the aging mouse brain by autoradiography, laser ablation inductively coupled plasma mass spectrometry and immunohistochemistry
Published in Metallomics (01-01-2010)“…Copper may play an important role in the brain in aging and neurodegenerative diseases. We compare the active Cu uptake, Cu-containing enzyme levels, and total…”
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7
Toll-like Receptor 3 and Geographic Atrophy in Age-Related Macular Degeneration
Published in The New England journal of medicine (02-10-2008)“…A variant of the toll-like receptor 3 (TLR3) provides protection against geographic atrophy, or “dry” age-related macular degeneration, and reduces apoptosis…”
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Correction: Lesions of the Lateral Habenula Increase Voluntary Ethanol Consumption and Operant Self-Administration, Block Yohimbine-Induced Reinstatement of Ethanol Seeking, and Attenuate Ethanol-Induced Conditioned Taste Aversion
Published in PloS one (23-05-2014)“…“Brain Institute” is incorrectly listed as an author for this article. (2014) Lesions of the Lateral Habenula Increase Voluntary Ethanol Consumption and…”
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Journal Article -
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Lesions of the Lateral Habenula Increase Voluntary Ethanol Consumption and Operant Self-Administration, Block Yohimbine-Induced Reinstatement of Ethanol Seeking, and Attenuate Ethanol-Induced Conditioned Taste Aversion: e92701
Published in PloS one (01-04-2014)“…The lateral habenula (LHb) plays an important role in learning driven by negative outcomes. Many drugs of abuse, including ethanol, have dose-dependent…”
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Journal Article -
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Abstract 3574: Study of the anti-glioma properties of the nitrone OKN007 by magnetic resonance imaging
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…The nitrone compound OKN007, a disulfonated derivative of phenyl-tert-butylnitrone, is known to have anti-glioma properties in a rat C6 glioma model. In this…”
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Journal Article -
11
Alcohol, stress, and decision making
Published 01-01-2013“…Alcoholism is enormously costly to both individuals and society, and alcoholics suffer from high rates of relapse. Both acute and chronic alcohol consumption…”
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Dissertation