Search Results - "Schwacha, M G"

Effect of gender and sex hormones on immune responses following shock by Angele, M K, Schwacha, M G, Ayala, A, Chaudry, I H

“…Several clinical and experimental studies show a gender dimorphism of the immune and organ responsiveness in the susceptibility to and morbidity from shock,…”
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In vivo blockage of nitric oxide with aminoguanidine inhibits immunosuppression induced by an attenuated strain of Salmonella typhimurium, potentiates Salmonella infection, and inhibits macrophage and polymorphonuclear leukocyte influx into the spleen by MACFARLANE, A. S, SCHWACHA, M. G, EISENSTEIN, T. K

“…Our laboratory has previously shown that after immunization with a strain of Salmonella typhimurium, SL3235, made avirulent by a blockage in the pathway of…”
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Thermal injury-induced immunosuppression in mice: the role of macrophage-derived reactive nitrogen intermediates by Schwacha, Martin G., Somers, Scott D.

“…Macrophages (MΦ) have been implicated in the suppression of lymphocyte function following thermal injury. Splenocytes isolated from C57BL/ 6NCR female mice 4–7…”
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Effect of yohimbine hydrochloride on erectile impotence: a double-blind study by Susset, J G, Tessier, C D, Wincze, J, Bansal, S, Malhotra, C, Schwacha, M G

“…A double-blind, partial crossover study on the therapeutic effect of yohimbine hydrochloride on erectile dysfunction was done in 82 sexually impotent patients…”
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Gender dimorphism in trauma-hemorrhage-induced thymocyte apoptosis by Angele, M K, Xu, Y X, Ayala, A, Schwacha, M G, Catania, R K, Cioffi, W G, Bland, K I, Chaudry, I H

“…Studies indicate that immune responses after trauma-hemorrhage are significantly depressed in males compared with enhanced immune responses in females under…”
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Salmonella typhimurium Infection in Mice Induces Nitric Oxide-Mediated Immunosuppression through a Natural Killer Cell-Dependent Pathway by SCHWACHA, M. G, MEISSLER, J. J, EISENSTEIN, T. K

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Thermal injury induces macrophage hyperactivity through pertussis toxin-sensitive and -insensitive pathways by Schwacha, M G, Somers, S D

“…C57BL/6 mice were subjected to a full thickness scald thermal injury covering 25% of their total body surface area, and thioglycollate elicited peritoneal…”
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Interleukin-12 is critical for induction of nitric oxide-mediated immunosuppression following vaccination of mice with attenuated Salmonella typhimurium by SCHWACHAT, M. G, EISENSTEIN, T. K

“…Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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The role of gamma delta T cells in the regulation of neutrophil-mediated tissue damage after thermal injury by Toth, B, Alexander, M, Daniel, T, Chaudry, I H, Hubbard, W J, Schwacha, M G

“…Thermal injury induces an inflammatory response that contributes to the development of secondary tissue damage. Neutrophil recruitment and activation are in…”
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Splenic Immune Suppression in Sepsis: A Role for IL-10-Induced Changes in P38 MAPK Signaling by Song, Grace Y., Chung, Chun-Shiang, Schwacha, Martin G., Jarrar, Doraid, Chaudry, Irshad H., Ayala, Alfred

“…Background.Studies have indicated that following the induction of sepsis, there is a late (24 h) generalized suppression of the immune response which is…”
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GENDER DIFFERENCES IN THE INFLAMMATORY RESPONSE AND SURVIVAL FOLLOWING HAEMORRHAGE AND SUBSEQUENT SEPSIS by Diodato, Michael D., Knöferl, Markus W., Schwacha, Martin G., Bland, Kirby I., Chaudry, Irshad H.

“…Studies have shown gender dimorphism in cell-mediated immune responses following haemorrhage, with depressed responses in young males and maintained or…”
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Attenuated salmonella vaccine-induced suppression of murine spleen cell responses to mitogen is mediated by macrophage nitric oxide: quantitative aspects by Huang, D, Schwacha, M.G, Eisenstein, T.K

“…Previous reports from our laboratory have shown that 7 days after infection of C3HeB/FeJ mice with an attenuated strain of Salmonella typhimurium, there is…”
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17 beta-Estradiol normalizes immune responses in ovariectomized females after trauma-hemorrhage by Knöferl, M W, Jarrar, D, Angele, M K, Ayala, A, Schwacha, M G, Bland, K I, Chaudry, I H

“…Recent studies indicate that immune responses in proestrus females are maintained after trauma-hemorrhage but markedly depressed in ovariectomized females…”
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Insights into the role of gamma delta T lymphocytes in the immunopathogenic response to thermal injury by Schwacha, M G, Ayala, A, Chaudry, I H

“…Studies have shown that cell-mediated immunity is markedly suppressed after thermal injury. T lymphocyte dysfunction and macrophage hyperactivity have been…”
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Divergent immune responses in male and female mice after trauma-hemorrhage: dimorphic alterations in T lymphocyte steroidogenic enzyme activities by Samy, T S, Knöferl, M W, Zheng, R, Schwacha, M G, Bland, K I, Chaudry, I H

“…Immune responses are suppressed in males, but not in proestrous females, after trauma-hemorrhage. Testosterone and 17beta-estradiol appear to be responsible…”
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Sex steroids regulate pro- and anti-inflammatory cytokine release by macrophages after trauma-hemorrhage by Angele, M K, Knöferl, M W, Schwacha, M G, Ayala, A, Cioffi, W G, Bland, K I, Chaudry, I H

“…Studies indicate that macrophage immune responses in males are depressed after trauma-hemorrhage, whereas they are enhanced in females under such conditions…”
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Nitric oxide mediates immunosuppression induced by Listeria monocytogenes infection : quantitative studies by MACFARLANE, A. S, DUAN HUANG, SCHWACHA, M. G, MEISSLER, J. J, GAUGHAN, J. P, EISENSTEIN, T. K

“…Our laboratory has shown that immunization of mice with an attenuated strain of Salmonella typhimuriuminduces profound suppression in the capacity of…”
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Respiratory burst capacity of activated macrophages is resistant to depression by erythrocyte phagocytosis by SCHWACHA, M. G, LOEGERING, D. J

“…The present study evaluated whether macrophage activation would reduce the depression in the capacity of macrophages to produce H2O2 following EIgG…”
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Are the immune responses different in middle-aged and young mice following bone fracture, tissue trauma and hemorrhage? by Kang, Shih-Ching, Matsutani, Takeshi, Choudhry, Mashkoor A., Schwacha, Martin G., Rue, Loring W., Bland, Kirby I., Chaudry, Irshad H.

“…Although immune responses following soft-tissue trauma–hemorrhage are markedly different in young (6–8 weeks) and aged (18–20 months) mice, it remains unknown…”
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Depression of macrophage respiratory burst capacity and arachidonic acid release after Fc receptor-mediated phagocytosis by Schwacha, MG, Gudewicz, PW, Snyder, JA, Loegering, DJ

“…The phagocytosis of IgG-coated erythrocytes (ElgG) by macrophages results in a subsequent depression of macrophage phagocytic function, respiratory burst…”
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