Search Results - "Schwab, Sibylle G"

How stress physically re-shapes the brain: Impact on brain cell shapes, numbers and connections in psychiatric disorders by Kaul, Dominic, Schwab, Sibylle G., Mechawar, Naguib, Matosin, Natalie

“…•Severe stress exposure is a strong risk factor for psychopathology.•We consolidate evidence of how stress exposure can physically reshape the…”
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Genetics of psychiatric disorders in the GWAS era: an update on schizophrenia by Schwab, Sibylle G., Wildenauer, Dieter B.

“…The influence of genetic factors in the development of schizophrenia has been convincingly demonstrated by family, twin, and adoption studies. The statistical…”
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Severe childhood and adulthood stress associates with neocortical layer-specific reductions of mature spines in psychiatric disorders by Kaul, Dominic, Smith, Caine C., Stevens, Julia, Fröhlich, Anna S., Binder, Elisabeth B., Mechawar, Naguib, Schwab, Sibylle G., Matosin, Natalie

“…Severe stress exposure causes the loss of dendritic spines on cortical pyramidal neurons and induces psychiatric-like symptoms in rodent models. These effects…”
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Genetic variation and susceptibility to schizophrenia: Work in progress by Schwab, Sibylle G

“…After finishing my pharmacy studies, I became interested in undertaking a PhD in the genetics of psychiatric disorders, specifically, the genetics of…”
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Secretion of Acid Sphingomyelinase is Affected by its Polymorphic Signal Peptide by Rhein, Cosima, Reichel, Martin, Mühle, Christiane, Rotter, Andrea, Schwab, Sibylle G., Kornhuber, Johannes

“…Background: Acid sphingomyelinase (ASM) catalyses the hydrolysis of sphingomyelin into ceramide, which acts as a lipid messenger that regulates important…”
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Sensorimotor Gating of Schizophrenia Patients Is Influenced by 5-HT2A Receptor Polymorphisms by Quednow, Boris B, Kühn, Kai-Uwe, Mössner, Rainald, Schwab, Sibylle G, Schuhmacher, Anna, Maier, Wolfgang, Wagner, Michael

“…Background Schizophrenia patients exhibit impairment in prepulse inhibition (PPI) of the acoustic startle response (ASR), suggesting a sensorimotor gating…”
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The Common Acid Sphingomyelinase Polymorphism p.G508R is Associated with Self-Reported Allergy by Reichel, Martin, Richter-Schmidinger, Tanja, Mühle, Christiane, Rhein, Cosima, Alexopoulos, Panagiotis, Schwab, Sibylle G., Gulbins, Erich, Kornhuber, Johannes

“…Background: Acid sphingomyelinase (ASM) is a key regulator of ceramide-dependent signalling pathways. Among others, activation of ASM can be induced by CD95 or…”
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Apoptotic engulfment pathway and schizophrenia by Chen, Xiangning, Sun, Cuie, Chen, Qi, O'Neill, F Anthony, Walsh, Dermot, Fanous, Ayman H, Chowdari, Kodavali V, Nimgaonkar, Vishwajit L, Scott, Adrian, Schwab, Sibylle G, Wildenauer, Dieter B, Che, Ronglin, Tang, Wei, Shi, Yongyong, He, Lin, Luo, Xiong-Jian, Su, Bing, Edwards, Todd L, Zhao, Zhongming, Kendler, Kenneth S

“…Apoptosis has been speculated to be involved in schizophrenia. In a previously study, we reported the association of the MEGF10 gene with the disease. In this…”
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Alterations in Astrocytic Regulation of Excitation and Inhibition by Stress Exposure and in Severe Psychopathology by Kaul, Dominic, Schwab, Sibylle G, Mechawar, Naguib, Ooi, Lezanne, Matosin, Natalie

“…Dysregulation of excitatory and inhibitory signaling is commonly observed in major psychiatric disorders, including schizophrenia, depression, and bipolar…”
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Dissecting the molecular biology of schizophrenia: A call for emphasising genetic and phenotypic heterogeneity: commentary on Torrey and Yolken (this issue) by Schwab, Sibylle G.

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Understanding the pathology of psychiatric disorders in refugees by Bartlett, Rachael, Sarnyai, Zoltan, Momartin, Shakeh, Ooi, Lezanne, Schwab, Sibylle G., Matosin, Natalie

“…•Displaced people are stress-exposed and at increased risk for psychopathology.•We summarise studies into the pathology of psychiatric disorders in…”
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DAOA/G72 predicts the progression of prodromal syndromes to first episode psychosis by Mössner, Rainald, Schuhmacher, Anna, Wagner, Michael, Quednow, Boris B., Frommann, Ingo, Kühn, Kai-Uwe, Schwab, Sibylle G., Rietschel, Marcella, Falkai, Peter, Wölwer, Wolfgang, Ruhrmann, Stephan, Bechdolf, Andreas, Gaebel, Wolfgang, Klosterkötter, Joachim, Maier, Wolfgang

“…The genetic factors determining the progression of prodromal syndromes to first episode schizophrenia have remained enigmatic to date. In a unique prospective…”
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Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond by Gaddis, Nathan, Mathur, Ravi, Marks, Jesse, Zhou, Linran, Quach, Bryan, Waldrop, Alex, Levran, Orna, Agrawal, Arpana, Randesi, Matthew, Adelson, Miriam, Jeffries, Paul W., Martin, Nicholas G., Degenhardt, Louisa, Montgomery, Grant W., Wetherill, Leah, Lai, Dongbing, Bucholz, Kathleen, Foroud, Tatiana, Porjesz, Bernice, Runarsdottir, Valgerdur, Tyrfingsson, Thorarinn, Einarsson, Gudmundur, Gudbjartsson, Daniel F., Webb, Bradley Todd, Crist, Richard C., Kranzler, Henry R., Sherva, Richard, Zhou, Hang, Hulse, Gary, Wildenauer, Dieter, Kelty, Erin, Attia, John, Holliday, Elizabeth G., McEvoy, Mark, Scott, Rodney J., Schwab, Sibylle G., Maher, Brion S., Gruza, Richard, Kreek, Mary Jeanne, Nelson, Elliot C., Thorgeirsson, Thorgeir, Stefansson, Kari, Berrettini, Wade H., Gelernter, Joel, Edenberg, Howard J., Bierut, Laura, Hancock, Dana B., Johnson, Eric Otto

“…Opioid addiction (OA) is moderately heritable, yet only rs1799971, the A118G variant in OPRM1 , has been identified as a genome-wide significant association…”
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Cis-Expression Quantitative Trait Loci Mapping Reveals Replicable Associations with Heroin Addiction in OPRM1 by Hancock, Dana B, Levy, Joshua L, Gaddis, Nathan C, Glasheen, Cristie, Saccone, Nancy L, Page, Grier P, Hulse, Gary K, Wildenauer, Dieter, Kelty, Erin A, Schwab, Sibylle G, Degenhardt, Louisa, Martin, Nicholas G, Montgomery, Grant W, Attia, John, Holliday, Elizabeth G, McEvoy, Mark, Scott, Rodney J, Bierut, Laura J, Nelson, Elliot C, Kral, Alex H, Johnson, Eric O

“…Abstract Background No opioid receptor, mu 1 ( OPRM1 ) gene polymorphisms, including the functional single nucleotide polymorphism (SNP) rs1799971, have been…”
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DNA sequence variants in the metabotropic glutamate receptor 3 and risk to schizophrenia: an association study by Schwab, Sibylle G, Plummer, Christie, Albus, Margot, Borrmann-Hassenbach, Margitta, Lerer, Bernard, Trixler, Matyas, Maier, Wolfgang, Wildenauer, Dieter B

“…Recent studies investigating the association of DNA variants in the metabotropic glutamate receptor gene (GRM3) with schizophrenia susceptibility revealed…”
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Improving polygenic prediction in ancestrally diverse populations by Ruan, Yunfeng, Lin, Yen-Feng, Feng, Yen-Chen Anne, Chen, Chia-Yen, Lam, Max, Guo, Zhenglin, Ahn, Yong Min, Akiyama, Kazufumi, Arai, Makoto, Baek, Ji Hyun, Chen, Wei J., Chung, Young-Chul, Feng, Gang, Fujii, Kumiko, Glatt, Stephen J., Ha, Kyooseob, Hattori, Kotaro, Higuchi, Teruhiko, Hishimoto, Akitoyo, Hong, Kyung Sue, Horiuchi, Yasue, Hwu, Hai-Gwo, Ikeda, Masashi, Ishiwata, Sayuri, Itokawa, Masanari, Iwata, Nakao, Joo, Eun-Jeong, Kahn, Rene S., Kim, Sung-Wan, Kim, Se Joo, Kim, Se Hyun, Kinoshita, Makoto, Kunugi, Hiroshi, Kusumawardhani, Agung, Lee, Jimmy, Lee, Byung Dae, Lee, Heon-Jeong, Liu, Jianjun, Liu, Ruize, Ma, Xiancang, Myung, Woojae, Numata, Shusuke, Ohmori, Tetsuro, Otsuka, Ikuo, Ozeki, Yuji, Schwab, Sibylle G., Shi, Wenzhao, Shimoda, Kazutaka, Sim, Kang, Sora, Ichiro, Tang, Jinsong, Toyota, Tomoko, Tsuang, Ming, Wildenauer, Dieter B., Won, Hong-Hee, Yoshikawa, Takeo, Zheng, Alice, Zhu, Feng, He, Lin, Sawa, Akira, Martin, Alicia R., Qin, Shengying, Huang, Hailiang, Ge, Tian

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Author Correction: Improving polygenic prediction in ancestrally diverse populations by Ruan, Yunfeng, Lin, Yen-Feng, Feng, Yen-Chen Anne, Chen, Chia-Yen, Lam, Max, Guo, Zhenglin, He, Lin, Sawa, Akira, Martin, Alicia R., Qin, Shengying, Huang, Hailiang, Ge, Tian

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Population Genetics of the Invasive Red Fox, Vulpes vulpes, in South-Eastern Australia by Watson, Kalynda M.-A., Mikac, Katarina M., Schwab, Sibylle G.

“…The use of genetic information in conservation biology has become more widespread with genetic information more readily available for non-model organisms. It…”
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DNA sequence variants of the FKBP5 gene are associated with unipolar depression by Zobel, Astrid, Schuhmacher, Anna, Jessen, Frank, Höfels, Susanne, von Widdern, Olrik, Metten, Martin, Pfeiffer, Ute, Hanses, Claudia, Becker, Tim, Rietschel, Marcella, Scheef, Lukas, Block, Wolfgang, Schild, Hans H., Maier, Wolfgang, Schwab, Sibylle G.

“…FKBP5 is a glucocorticoid receptor-regulating co-chaperone of hsp-90 and, therefore, is suggested to play a role in the regulation of the…”
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Support for Association of Schizophrenia with Genetic Variation in the 6p22.3 Gene, Dysbindin, in Sib-Pair Families with Linkage and in an Additional Sample of Triad Families by Schwab, Sibylle G., Knapp, Michael, Mondabon, Stephanie, Hallmayer, Joachim, Borrmann-Hassenbach, Margitta, Albus, Margot, Lerer, Bernard, Rietschel, Marcella, Trixler, Matyas, Maier, Wolfgang, Wildenauer, Dieter B.

“…Genetic variants in a gene on 6p22.3, dysbindin, have been shown recently to be associated with schizophrenia (Straub et al. 2002 a ). There is no doubt that…”
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