Search Results - "Schutkowski, M"

Analysis of Toxoplasma gondii clonal type-specific antibody reactions in experimentally infected turkeys and chickens by Maksimov, P., Basso, W., Zerweck, J., Schutkowski, M., Reimer, U., Maksimov, A., Conraths, F.J., Schares, G.

“…[Display omitted] •Chickens and turkeys develop a Toxoplasma gondii clonal type-specific IgY response.•Each bird recognised its own peptide pattern, which…”
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A protease-free assay for peptidyl prolyl cis/trans isomerases using standard peptide substrates by Janowski, B, Wöllner, S, Schutkowski, M, Fischer, G

“…Peptidyl prolyl cis/trans isomerases (PPIases) are ubiquitous and abundant enzymes catalyzing peptide bond cis/trans isomerization adjacent to proline in…”
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MO25α/β interact with STRADα/β enhancing their ability to bind, activate and localize LKB1 in the cytoplasm by Boudeau, Jérôme, Baas, Annette F., Deak, Maria, Morrice, Nick A., Kieloch, Agnieszka, Schutkowski, Mike, Prescott, Alan R., Clevers, Hans C., Alessi, Dario R.

“…Mutations in the LKB1 protein kinase result in the inherited Peutz Jeghers cancer syndrome. LKB1 has been implicated in regulating cell proliferation and…”
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Peptide Arrays for Kinase Profiling by Schutkowski, Mike, Reineke, Ulrich, Reimer, Ulf

“…Hundreds and thousands of simultaneous kinase assays are possible by using peptide arrays. In this minireview, we summarize production principles, library…”
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The Speed Limit for Protein Folding Measured by Triplet-Triplet Energy Transfer by Bieri, Oliver, Wirz, Jakob, Hellrung, Bruno, Schutkowski, Mike, Drewello, Mario, Kiefhaber, Thomas

“…A direct measure of intramolecular chain diffusion is obtained by the determination of triplet-triplet energy-transfer rates between a donor and an acceptor…”
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Validation of peptide epitope microarray experiments and extraction of quality data by Nahtman, Tatjana, Jernberg, Alexander, Mahdavifar, Shahnaz, Zerweck, Johannes, Schutkowski, Mike, Maeurer, Markus, Reilly, Marie

“…Within the last decade, the development of antigen microarray slides has enabled the simultaneous measurement of serum reactivity to hundreds of peptides in a…”
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Whole CMV proteome pattern recognition analysis after HSCT identifies unique epitope targets associated with the CMV status by Pérez-Bercoff, Lena, Valentini, Davide, Gaseitsiwe, Simani, Mahdavifar, Shahnaz, Schutkowski, Mike, Poiret, Thomas, Pérez-Bercoff, Åsa, Ljungman, Per, Maeurer, Markus J

“…Cytomegalovirus (CMV) infection represents a vital complication after Hematopoietic Stem Cell Transplantation (HSCT). We screened the entire CMV proteome to…”
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Pattern recognition in pulmonary tuberculosis defined by high content peptide microarray chip analysis representing 61 proteins from M. tuberculosis by Gaseitsiwe, Simani, Valentini, Davide, Mahdavifar, Shahnaz, Magalhaes, Isabelle, Hoft, Daniel F, Zerweck, Johannes, Schutkowski, Mike, Andersson, Jan, Reilly, Marie, Maeurer, Markus J

“…Serum antibody-based target identification has been used to identify tumor-associated antigens (TAAs) for development of anti-cancer vaccines. A similar…”
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Peptide arrays for enzyme profiling by Thiele, Alexandra, Zerweck, Johannes, Schutkowski, Mike

“…Enzymes are key molecules in signal transduction pathways. However, only a small fraction of more than 500 predicted human kinases, 250 proteases and 250…”
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Side-chain effects on peptidyl-prolyl cis/trans isomerisation by Reimer, Ulf, Scherer, Gerd, Drewello, Mario, Kruber, Susanne, Schutkowski, Mike, Fischer, Gunter

“…Peptidyl-prolyl cis/trans isomerisation has been frequently found as a rate limiting step in the folding of proteins. In order to determine whether the nature…”
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Antibody signatures defined by high-content peptide microarray analysis by Masch, Antonia, Zerweck, Johannes, Reimer, Ulf, Wenschuh, Holger, Schutkowski, Mike

“…Circulating antibodies are highly selective binding reagents directed to a vast repertoire of antigens. Candidate antigens displayed as overlapping peptides on…”
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Target specificity analysis of the Abl kinase using peptide microarray data by Rychlewski, Leszek, Kschischo, Maik, Dong, Liying, Schutkowski, Mike, Reimer, Ulf

“…Protein kinases play an important role in cellular signalling. The reliable prediction of their substrates is of high importance for the deciphering of…”
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Sequence-Specific and Phosphorylation-Dependent Proline Isomerization: A Potential Mitotic Regulatory Mechanism by Yaffe, Michael B., Schutkowski, Mike, Shen, Minhui, Zhou, Xiao Zhen, Stukenberg, P. Todd, Rahfeld, Jens-Ulrich, Xu, Jian, Kuang, Jian, Kirschner, Marc W., Fischer, Gunter, Cantley, Lewis C., Lu, Kun Ping

“…Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase (PPIase) that is distinct from members of two other families of conventional PPIases,…”
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Nanomolar Inhibitors of the Peptidyl Prolyl Cis/Trans Isomerase Pin1 from Combinatorial Peptide Libraries by Wildemann, Dirk, Erdmann, Frank, Alvarez, Birte Hernandez, Stoller, Gerlind, Zhou, Xiao Z, Fanghänel, Jörg, Schutkowski, Mike, Lu, Kun P, Fischer, Gunter

“…The peptidyl prolyl cis/trans isomerase Pin1 has been implicated in the development of cancer, Alzheimer's disease and asthma, but highly specific and potent…”
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High-Content Peptide Microarrays for Deciphering Kinase Specificity and Biology by Schutkowski, Mike, Reimer, Ulf, Panse, Sören, Dong, Liying, Lizcano, Jose M., Alessi, Dario R., Schneider-Mergener, Jens

“…Thousands of kinase assays at one stroke are possible by using high‐content peptide microarrays. Such experiments deliver information regarding peptidic kinase…”
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Rotational Barriers of cis/trans Isomerization of Proline Analogues and Their Catalysis by Cyclophilin by Kern, Dorothee, Schutkowski, Mike, Drakenberg, Torbjörn

“…The rotational barriers for cis/trans isomerization of different proline analogues have been investigated by dynamic 1H NMR spectroscopy. To this end the…”
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High-density peptide microarrays for reliable identification of phosphorylation sites and upstream kinases by Thiele, Alexandra, Zerweck, Johannes, Weiwad, Matthias, Fischer, Gunter, Schutkowski, Mike

“…The human genome encodes about 25,000 genes. This number seems to be very small compared to the multitude of different protein functions in highly regulated…”
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High density peptide microarrays for proteome-wide fingerprinting of kinase activities in cell lysates by Thiele, Alexandra, Weiwad, Matthias, Zerweck, Johannes, Fischer, Gunter, Schutkowski, Mike

“…Protein function is highly regulated in pathways that are responsible for complex biochemical mechanisms such as growth, metabolism, and signal transduction…”
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A model of the active site of dipeptidyl peptidase IV predicted by comparative molecular field analysis and molecular modelling simulations by Brandt, W, Lehmann, T, Thondorf, I, Born, I, Schutkowski, M, Rahfeld, J U, Neubert, K, Barth, A

“…A molecular model of the active site of the serine protease dipeptidyl peptidase IV (DPP IV or CD26) has been developed on the basis of comparative molecular…”
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Barriers to Rotation of Secondary Amide Peptide Bonds by Scherer, Gerd, Kramer, Michael L, Schutkowski, Mike, Reimer, Ulf, Fischer, Gunter

“…We present results on the identification and molecular characterization of conformers with secondary cis amide peptide bonds for a number of oligopeptides…”
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