Search Results - "Schuster, Flora"
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Development of an optimized tetracycline-inducible expression system to increase the accumulation of interleukin-10 in tobacco BY-2 suspension cells
Published in BMC biotechnology (11-07-2012)“…Plant cell suspension cultures can be used for the production of valuable pharmaceutical and industrial proteins. When the recombinant protein is secreted into…”
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2
Transient expression of a tumor-specific single-chain fragment and a chimeric antibody in tobacco leaves
Published in Proceedings of the National Academy of Sciences - PNAS (28-09-1999)“…To evaluate the expression of different forms of a tumor-specific antibody in plants, we adapted a recently described Agrobacterium-mediated transient…”
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3
Viral and murine interleukin-10 are correctly processed and retain their biological activity when produced in tobacco
Published in BMC biotechnology (19-03-2009)“…Interleukin-10 (IL-10) is a potent anti-inflammatory cytokine, with therapeutic applications in several autoimmune and inflammatory diseases. Oral…”
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Targeting Tryptophan Decarboxylase to Selected Subcellular Compartments of Tobacco Plants Affects Enzyme Stability and in vivo Function and Leads to a Lesion-Mimic Phenotype
Published in Plant physiology (Bethesda) (01-07-2002)“…Tryptophan decarboxylase (TDC) is a cytosolic enzyme that catalyzes an early step of the terpenoid indole alkaloid biosynthetic pathway by decarboxylation of…”
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5
Towards molecular farming in the future: using plant-cell-suspension cultures as bioreactors
Published in Biotechnology and applied biochemistry (01-10-1999)“…Plant‐suspension cells are an in vitro system that can be used for recombinant protein production under carefully controlled certified conditions…”
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Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200-L orbitally-shaken disposable bioreactor
Published in Biotechnology and bioengineering (01-02-2015)“…ABSTRACT Tobacco BY‐2 cells have emerged as a promising platform for the manufacture of biopharmaceutical proteins, offering efficient protein secretion,…”
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More for less: Improving the biomass yield of a pear cell suspension culture by design of experiments
Published in Scientific reports (18-03-2016)“…Plant cell suspension cultures are widely used for the production of recombinant proteins and secondary metabolites. One of the most important steps during…”
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A carcinoembryonic antigen‐specific diabody produced in tobacco
Published in The FASEB journal (01-03-2002)“…ABSTRACT The feasibility of using tobacco for production of a recombinant antibody (T84.66/GS8 diabody) directed against the carcinoembryonic antigen (CEA) and…”
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Targeting trytophan decarboxylase to selected subcellular compartments of tobacco plants affects enzyme stability and in vivo function and leads to a lesion-mimic phenotype
Published in Plant physiology (Bethesda) (01-07-2002)“…Tryptophan decarboxylase (TDC) is a cytosolic enzyme that catalyzes an early step of the terpenoid indole alkaloid biosynthetic pathway by decarboxylation of…”
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Journal Article -
10
Targeting Tryptophan Decarboxylase to Selected Subcellular Compartments of Tobacco Plants Affects Enzyme Stability and in Vivo Function and Leads to a Lesion-Mimic Phenotype1
Published in Plant physiology (Bethesda) (01-07-2002)“…Tryptophan decarboxylase (TDC) is a cytosolic enzyme that catalyzes an early step of the terpenoid indole alkaloid biosynthetic pathway by decarboxylation of l…”
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11
Measuring Exposure to Pro- and Anti-tobacco Marketing Among Adolescents: Intercorrelations Among Measures and Associations With Smoking Status
Published in Journal of health communication (01-01-2001)“…Exposure to tobacco - related marketing has been implicated as one of the risk factors for tobacco use among adolescents. However, tobacco - related marketing…”
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