Search Results - "Schuster, Brooke"

Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids by Schuster, Brooke, Junkin, Michael, Kashaf, Sara Saheb, Romero-Calvo, Isabel, Kirby, Kori, Matthews, Jonathan, Weber, Christopher R., Rzhetsky, Andrey, White, Kevin P., Tay, Savaş

“…Three-dimensional (3D) cell culture technologies, such as organoids, are physiologically relevant models for basic and clinical applications. Automated…”
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OrganoID: A versatile deep learning platform for tracking and analysis of single-organoid dynamics by Matthews, Jonathan M, Schuster, Brooke, Kashaf, Sara Saheb, Liu, Ping, Ben-Yishay, Rakefet, Ishay-Ronen, Dana, Izumchenko, Evgeny, Shen, Le, Weber, Christopher R, Bielski, Margaret, Kupfer, Sonia S, Bilgic, Mustafa, Rzhetsky, Andrey, Tay, Savaş

“…Organoids have immense potential as ex vivo disease models for drug discovery and personalized drug screening. Dynamic changes in individual organoid…”
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Development and Exploration of New Automated Tools to Accelerate Research on Tissue and Tumor Model Systems by Schuster, Brooke Elizabeth

“…Drug attrition rates for cancer are much higher than in other therapeutic areas. There is an urgent need for appropriate tumor models that can physiologically…”
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Differential Adhesion Selection for Enrichment of Tendon-Derived Progenitor Cells During In Vitro Culture by Durgam, Sushmitha, Schuster, Brooke, Cymerman, Anna, Stewart, Allison, Stewart, Matthew

“…Preplating, a technique used to separate rapidly adherent fibroblasts from the less-adherent progenitor cells, has been used successfully to isolate skeletal…”
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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 by Drayman, Nir, DeMarco, Jennifer K., Jones, Krysten A., Azizi, Saara-Anne, Froggatt, Heather M., Tan, Kemin, Maltseva, Natalia Ivanovna, Chen, Siquan, Nicolaescu, Vlad, Dvorkin, Steve, Furlong, Kevin, Kathayat, Rahul S., Firpo, Mason R., Mastrodomenico, Vincent, Bruce, Emily A., Schmidt, Madaline M., Jedrzejczak, Robert, Muñoz-Alía, Miguel Á., Schuster, Brooke, Nair, Vishnu, Han, Kyu-yeon, O’Brien, Amornrat, Tomatsidou, Anastasia, Meyer, Bjoern, Vignuzzi, Marco, Missiakas, Dominique, Botten, Jason W., Brooke, Christopher B., Lee, Hyun, Baker, Susan C., Mounce, Bryan C., Heaton, Nicholas S., Severson, William E., Palmer, Kenneth E., Dickinson, Bryan C., Joachimiak, Andrzej, Randall, Glenn, Tay, Savaş

“…Targeting the main protease of SARS-CoV-2 Inside host cells, the RNA genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is translated into…”
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Masitinib is a Broad Coronavirus 3CL Inhibitor that Blocks Replication of SARS-CoV-2 by Drayman, Nir, DeMarco, Jennifer K., Jones, Krysten A., Azizi, Saara-Anne, Froggatt, Heather M., Tan, Kemin, Maltseva, Natalia Ivanovna, Chen, Siquan, Nicolaescu, Vlad, Dvorkin, Steve, Furlong, Kevin, Kathayat, Rahul S., Firpo, Mason R., Mastrodomenico, Vincent, Bruce, Emily A., Schmidt, Madaline M., Jedrzejczak, Robert, Muñoz-Alía, Miguel Á., Schuster, Brooke, Nair, Vishnu, Han, Kyu-yeon, O’Brien, Amornrat, Tomatsidou, Anastasia, Meyer, Bjoern, Vignuzzi, Marco, Missiakas, Dominique, Botten, Jason W., Brooke, Christopher B., Lee, Hyun, Baker, Susan C., Mounce, Bryan C., Heaton, Nicholas S., Severson, William E., Palmer, Kenneth E., Dickinson, Bryan C., Joachimiak, Andrzej, Randall, Glenn, Tay, Savaş

“…There is an urgent need for antiviral agents that treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We screened a library of 1900…”
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Masitinib is a broad coronavirus 3CL inhibitor that effectively blocks replication of SARS-CoV-2 by Drayman, Nir, DeMarco, Jennifer K, Jones, Krysten A., Azizi, Saara-Anne, Froggatt, Heather M., Tan, Kemin, Maltseva, Natalia Ivanovna, Chen, Siquan, Nicolaescu, Vlad, Dvorkin, Steve, Furlong, Kevin, Kathayat, Rahul S., Firpo, Mason R., Mastrodomenico, Vincent, Bruce, Emily A., Schmidt, Madaline M., Jedrzejczak, Robert, Muñoz-Alía, Miguel Á., Schuster, Brooke, Nair, Vishnu, Han, Kyu-yeon, O’Brien, Amornrat, Tomatsidou, Anastasia, Meyer, Bjoern, Vignuzzi, Marco, Missiakas, Dominique, Botten, Jason W., Brooke, Christopher B., Lee, Hyun, Baker, Susan C., Mounce, Bryan C., Heaton, Nicholas S., Severson, William E, Palmer, Kenneth E, Dickinson, Bryan C., Jaochimiak, Andrzej, Randall, Glenn, Tay, Savaş

“…There is an urgent need for antiviral agents that treat SARS-CoV-2 infection. We screened a library of 1,900 clinically safe drugs against OC43, a human…”
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Modifying Practitioner Attitudes Toward and Use of Prolonged Exposure Therapy for PTSD Using an Online Continuing Education Course by Schuster, Brooke S

“…Although Prolonged Exposure Therapy (PE) has been shown to be one of the most effective treatments for posttraumatic stress disorder (PTSD) in research trials,…”
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