Search Results - "Schurmann, Sebastian"

Label-Free Characterization and Quantification of Mucosal Inflammation in Common Murine Colitis Models With Multiphoton Imaging by Kreiss, Lucas, Thoma, Oana-Maria, Lemire, Sarah, Lechner, Kristina, Carlé, Birgitta, Dilipkumar, Ashwathama, Kunert, Timo, Scheibe, Kristina, Heichler, Christina, Merten, Anna-Lena, Weigmann, Benno, Neufert, Clemens, Hildner, Kai, Vieth, Michael, Neurath, Markus F, Friedrich, Oliver, Schürmann, Sebastian, Waldner, Maximilian J

“…Abstract Background Clinical challenges in inflammatory bowel diseases require microscopic in vivo evaluation of inflammation. Here, label-free imaging holds…”
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Automated Multiscale Morphometry of Muscle Disease From Second Harmonic Generation Microscopy Using Tensor-Based Image Processing by Garbe, Christoph S., Buttgereit, Andreas, Schurmann, Sebastian, Friedrich, Oliver

“…Practically, all chronic diseases are characterized by tissue remodeling that alters organ and cellular function through changes to normal organ architecture…”
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Interferon regulatory factor 1 (IRF-1) promotes intestinal group 3 innate lymphoid responses during Citrobacter rodentium infection by Schmalzl, Angelika, Leupold, Tamara, Kreiss, Lucas, Waldner, Maximilian, Schürmann, Sebastian, Neurath, Markus F., Becker, Christoph, Wirtz, Stefan

“…Group 3 innate lymphoid cells (ILC3s) are crucial mediators of immunity and epithelial barrier function during immune responses against extracellular bacteria…”
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Estimating the 3D Pore Size Distribution of Biopolymer Networks from Directionally Biased Data by Lang, Nadine R., Münster, Stefan, Metzner, Claus, Krauss, Patrick, Schürmann, Sebastian, Lange, Janina, Aifantis, Katerina E., Friedrich, Oliver, Fabry, Ben

“…The pore size of biopolymer networks governs their mechanical properties and strongly impacts the behavior of embedded cells. Confocal reflection microscopy…”
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Natural NADH and FAD Autofluorescence as Label-Free Biomarkers for Discriminating Subtypes and Functional States of Immune Cells by Lemire, Sarah, Thoma, Oana-Maria, Kreiss, Lucas, Völkl, Simon, Friedrich, Oliver, Neurath, Markus F, Schürmann, Sebastian, Waldner, Maximilian J

“…Immune cell activity is a major factor for disease progression in inflammatory bowel diseases (IBD). Classifying the type and functional state of immune cells…”
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Label‐Free Multiphoton Endomicroscopy for Minimally Invasive In Vivo Imaging by Dilipkumar, Ashwathama, Al‐Shemmary, Alaa, Kreiß, Lucas, Cvecek, Kristian, Carlé, Birgitta, Knieling, Ferdinand, Gonzales Menezes, Jean, Thoma, Oana‐Maria, Schmidt, Michael, Neurath, Markus F., Waldner, Maximilian, Friedrich, Oliver, Schürmann, Sebastian

“…Multiphoton microscopy of cellular autofluorescence and second harmonic generation from collagen facilitates imaging of living cells and tissues without the…”
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Imaging of Mucosal Inflammation: Current Technological Developments, Clinical Implications, and Future Perspectives by Waldner, Maximilian J, Rath, Timo, Schürmann, Sebastian, Bojarski, Christian, Atreya, Raja

“…In recent years, various technological developments markedly improved imaging of mucosal inflammation in patients with inflammatory bowel diseases. Although…”
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Early signs of architectural and biomechanical failure in isolated myofibers and immortalized myoblasts from desmin-mutant knock-in mice by Diermeier, Stefanie, Iberl, Julian, Vetter, Kristina, Haug, Michael, Pollmann, Charlotte, Reischl, Barbara, Buttgereit, Andreas, Schürmann, Sebastian, Spörrer, Marina, Goldmann, Wolfgang H., Fabry, Ben, Elhamine, Fatiha, Stehle, Robert, Pfitzer, Gabriele, Winter, Lilli, Clemen, Christoph S., Herrmann, Harald, Schröder, Rolf, Friedrich, Oliver

“…In striated muscle, desmin intermediate filaments interlink the contractile myofibrillar apparatus with mitochondria, nuclei, and the sarcolemma. The desmin…”
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Raster-Scanning Optoacoustic Mesoscopy for Gastrointestinal Imaging at High Resolution by Knieling, Ferdinand, Gonzales Menezes, Jean, Claussen, Jing, Schwarz, Mathias, Neufert, Clemens, Fahlbusch, Fabian B., Rath, Timo, Thoma, Oana-Maria, Kramer, Viktoria, Menchicchi, Bianca, Kersten, Christina, Scheibe, Kristina, Schürmann, Sebastian, Carlé, Birgitta, Rascher, Wolfgang, Neurath, Markus F., Ntziachristos, Vasilis, Waldner, Maximilian J.

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An advanced optical clearing protocol allows label-free detection of tissue necrosis via multiphoton microscopy in injured whole muscle by Schneidereit, Dominik, Bröllochs, Anita, Ritter, Paul, Kreiß, Lucas, Mokhtari, Zeinab, Beilhack, Andreas, Krönke, Gerhard, Ackermann, Jochen A, Faas, Maria, Grüneboom, Anika, Schürmann, Sebastian, Friedrich, Oliver

“…Structural remodeling or damage as a result of disease or injury is often not evenly distributed throughout a tissue but strongly depends on localization and…”
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PiezoGRIN: A High‐Pressure Chamber Incorporating GRIN Lenses for High‐Resolution 3D‐Microscopy of living Cells and Tissues by Schneidereit, Dominik, Schürmann, Sebastian, Friedrich, Oliver

“…A high‐pressure optical chamber, PiezoGRIN, that facilitates label‐free 3D high‐resolution live‐cell multiphoton microscopy in thick tissue samples is…”
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Stretch in Focus : 2D Inplane Cell Stretch Systems for Studies of Cardiac Mechano-Signaling by Friedrich, Oliver, Merten, Anna-Lena, Schneidereit, Dominik, Guo, Yang, Schürmann, Sebastian, Martinac, Boris

“…Mechanobiology is a rapidly growing interdisciplinary research field, involving biophysics, molecular and cell biology, biomedical engineering, and medicine…”
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A novel modular opto-biomechatronics bioreactor for simultaneous isotropic mechanical stretch application and fluorescence microscopy under cell and tissue culture conditions by Merten, Anna-Lena, Schöler, Ulrike, Lesko, Christian, Kreiß, Lucas, Schneidereit, Dominik, Linsenmeier, Fabian, Stolz, Axel, Rappl, Sebastian, Ali, Mohamed, Potié, Tim, Ahmed, Adel, Morales-Dalmau, Jordi, Saam, Jan, Schürmann, Sebastian, Friedrich, Oliver

“…Mechanical stresses are an environmental challenge virtually all tissues in the body are exposed to and thus, are of fundamental interest to study cell…”
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Innovative Diagnostic Endoscopy in Inflammatory Bowel Diseases: From High-Definition to Molecular Endoscopy by Bojarski, Christian, Waldner, Maximilian, Rath, Timo, Schürmann, Sebastian, Neurath, Markus F., Atreya, Raja, Siegmund, Britta

“…High-definition endoscopy is one essential step in the initial diagnosis of inflammatory bowel disease (IBD) characterizing the extent and severity of…”
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SEMPAI: a Self-Enhancing Multi-Photon Artificial Intelligence for Prior-Informed Assessment of Muscle Function and Pathology by Mühlberg, Alexander, Ritter, Paul, Langer, Simon, Goossens, Chloë, Nübler, Stefanie, Schneidereit, Dominik, Taubmann, Oliver, Denzinger, Felix, Nörenberg, Dominik, Haug, Michael, Schürmann, Sebastian, Horstmeyer, Roarke, Maier, Andreas K, Goldmann, Wolfgang H, Friedrich, Oliver, Kreiss, Lucas

“…Deep learning (DL) shows notable success in biomedical studies. However, most DL algorithms work as black boxes, exclude biomedical experts, and need extensive…”
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Structure-Function Relationships in Muscle Fibres: MyoRobot Online Assessment of Muscle Fibre Elasticity and Sarcomere Length Distributions by Haug, Michael, Ritter, Paul, Michael, Mena, Reischl, Barbara, Schurmann, Sebastian, Prols, Gerhard, Friedrich, Oliver

“…Objective: Muscle biomechanics is set by the spacing of repetitive striation patterns of individual sarcomeres within single muscle fibres of stacked…”
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Anti‐β7 integrin treatment impedes the recruitment on non‐classical monocytes to the gut and delays macrophage‐mediated intestinal wound healing by Sommer, Katrin, Heidbreder, Karin, Kreiss, Lucas, Dedden, Mark, Paap, Eva‐Maria, Wiendl, Maximilian, Becker, Emily, Atreya, Raja, Müller, Tanja M., Atreya, Imke, Waldner, Maximilian, Schürmann, Sebastian, Friedrich, Oliver, Neurath, Markus F., Zundler, Sebastian

“…Background Closing mucosal defects to reach mucosal healing is an important goal of therapy in inflammatory bowel disease (IBD). Among other cells,…”
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Velocity distributions of single F-actin trajectories from a fluorescence image series using trajectory reconstruction and optical flow mapping by von Wegner, Frederic, Ober, Tobias, Weber, Cornelia, Schürmann, Sebastian, Winter, René, Friedrich, Oliver, Fink, Rainer H A, Vogel, Martin

“…We present an approach for the computation of single-object velocity statistics in a noisy fluorescence image series. The algorithm is applied to molecular…”
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TCT-271 Drug-Coated Reflow Temporary Spur Systems: Inhibition of Neointimal Proliferation in Porcine Peripheral Arteries by Brunacci, Nadia, Schurmann-Kaufeld, Sebastian, Haase, Tobias, Jimenez, Teo

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High-content method for mechanosignaling studies using IsoStretcher technology and quantitative Ca2+ imaging applied to Piezo1 in cardiac HL-1 cells by Merten, Anna-Lena, Schöler, Ulrike, Guo, Yang, Linsenmeier, Fabian, Martinac, Boris, Friedrich, Oliver, Schürmann, Sebastian

“…The importance of mechanosensory transduction pathways in cellular signalling has prominently come to focus in the last decade with the discovery of the Piezo…”
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