Search Results - "Schurmann, Felix"

Metaball skinning of synthetic astroglial morphologies into realistic mesh models for visual analytics and in silico simulations by Abdellah, Marwan, Foni, Alessandro, Zisis, Eleftherios, Guerrero, Nadir Román, Lapere, Samuel, Coggan, Jay S, Keller, Daniel, Markram, Henry, Schürmann, Felix

“…MOTIVATIONAstrocytes, the most abundant glial cells in the mammalian brain, have an instrumental role in developing neuronal circuits. They contribute to the…”
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Community-based reconstruction and simulation of a full-scale model of the rat hippocampus CA1 region by Romani, Armando, Antonietti, Alberto, Bella, Davide, Budd, Julian, Giacalone, Elisabetta, Kurban, Kerem, Sáray, Sára, Abdellah, Marwan, Arnaudon, Alexis, Boci, Elvis, Colangelo, Cristina, Courcol, Jean-Denis, Delemontex, Thomas, Ecker, András, Falck, Joanne, Favreau, Cyrille, Gevaert, Michael, Hernando, Juan B., Herttuainen, Joni, Ivaska, Genrich, Kanari, Lida, Kaufmann, Anna-Kristin, King, James Gonzalo, Kumbhar, Pramod, Lange, Sigrun, Lu, Huanxiang, Lupascu, Carmen Alina, Migliore, Rosanna, Petitjean, Fabien, Planas, Judit, Rai, Pranav, Ramaswamy, Srikanth, Reimann, Michael W., Riquelme, Juan Luis, Román Guerrero, Nadir, Shi, Ying, Sood, Vishal, Sy, Mohameth François, Van Geit, Werner, Vanherpe, Liesbeth, Freund, Tamás F., Mercer, Audrey, Muller, Eilif, Schürmann, Felix, Thomson, Alex M., Migliore, Michele, Káli, Szabolcs, Markram, Henry

“…The CA1 region of the hippocampus is one of the most studied regions of the rodent brain, thought to play an important role in cognitive functions such as…”
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Modernizing the NEURON Simulator for Sustainability, Portability, and Performance by Awile, Omar, Kumbhar, Pramod, Cornu, Nicolas, Dura-Bernal, Salvador, King, James Gonzalo, Lupton, Olli, Magkanaris, Ioannis, McDougal, Robert A, Newton, Adam J H, Pereira, Fernando, Săvulescu, Alexandru, Carnevale, Nicholas T, Lytton, William W, Hines, Michael L, Schürmann, Felix

“…The need for reproducible, credible, multiscale biological modeling has led to the development of standardized simulation platforms, such as the widely-used…”
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Population history of chimpanzees introduced to Lake Victoria’s Rubondo Island by Msindai, Josephine N., Roos, Christian, Schürmann, Felix, Sommer, Volker

“…Between 1966 to 1969, Bernhard Grzimek (Frankfurt Zoological Society, FZS) introduced chimpanzees ( Pan troglodytes ) previously held in European institutions…”
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ARC: An Open Web-Platform for Request/Supply Matching for a Prioritized and Controlled COVID-19 Response by Courcol, Jean-Denis, Invernizzi, Cédric F, Landry, Zachary C, Minisini, Mikhaél, Baumgartner, Dieter A, Bonhoeffer, Sebastian, Chabriw, Barbara, Clerc, Estelle E, Daniels, Michael, Getta, Pavlo, Girod, Matthieu, Kazala, Kinga, Markram, Henry, Pasqualini, Axel, Martínez-Pérez, Clara, Peaudecerf, François J, Peaudecerf, Margit S, Pfreundt, Ulrike, Roller, Benjamin R K, Słomka, Jonasz, Vasse, Marie, Wheeler, Jeanette D, Metzger, César M J A, Stocker, Roman, Schürmann, Felix

“…In 2020 the world was hit by the COVID-19 pandemic putting entire governments and civil societies in crisis mode. Around the globe unprecedented shortages of…”
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Comparison of neuronal spike exchange methods on a Blue Gene/P supercomputer by Hines, Michael, Kumar, Sameer, Schürmann, Felix

“…For neural network simulations on parallel machines, interprocessor spike communication can be a significant portion of the total simulation time. The…”
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Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties by Hay, Etay, Hill, Sean, Schürmann, Felix, Markram, Henry, Segev, Idan

“…The thick-tufted layer 5b pyramidal cell extends its dendritic tree to all six layers of the mammalian neocortex and serves as a major building block for the…”
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NeuroMorphoVis: a collaborative framework for analysis and visualization of neuronal morphology skeletons reconstructed from microscopy stacks by Abdellah, Marwan, Hernando, Juan, Eilemann, Stefan, Lapere, Samuel, Antille, Nicolas, Markram, Henry, Schürmann, Felix

“…Abstract Motivation From image stacks to computational models, processing digital representations of neuronal morphologies is essential to neuroscientific…”
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Understanding Computational Costs of Cellular-Level Brain Tissue Simulations Through Analytical Performance Models by Cremonesi, Francesco, Schürmann, Felix

“…Computational modeling and simulation have become essential tools in the quest to better understand the brain’s makeup and to decipher the causal…”
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Statistical connectivity provides a sufficient foundation for specific functional connectivity in neocortical neural microcircuits by Hill, Sean L, Wang, Yun, Riachi, Imad, Schürmann, Felix, Markram, Henry

“…It is well-established that synapse formation involves highly selective chemospecific mechanisms, but how neuron arbors are positioned before synapse formation…”
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CoreNEURON : An Optimized Compute Engine for the NEURON Simulator by Kumbhar, Pramod, Hines, Michael, Fouriaux, Jeremy, Ovcharenko, Aleksandr, King, James, Delalondre, Fabien, Schürmann, Felix

“…The NEURON simulator has been developed over the past three decades and is widely used by neuroscientists to model the electrical activity of neuronal…”
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The Scientific Case for Brain Simulations by Einevoll, Gaute T., Destexhe, Alain, Diesmann, Markus, Grün, Sonja, Jirsa, Viktor, de Kamps, Marc, Migliore, Michele, Ness, Torbjørn V., Plesser, Hans E., Schürmann, Felix

“…A key element of the European Union’s Human Brain Project (HBP) and other large-scale brain research projects is the simulation of large-scale model networks…”
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Reconstruction and Simulation of Neocortical Microcircuitry by Markram, Henry, Muller, Eilif, Ramaswamy, Srikanth, Reimann, Michael W., Abdellah, Marwan, Sanchez, Carlos Aguado, Ailamaki, Anastasia, Alonso-Nanclares, Lidia, Antille, Nicolas, Arsever, Selim, Kahou, Guy Antoine Atenekeng, Berger, Thomas K., Bilgili, Ahmet, Buncic, Nenad, Chalimourda, Athanassia, Chindemi, Giuseppe, Courcol, Jean-Denis, Delalondre, Fabien, Delattre, Vincent, Druckmann, Shaul, Dumusc, Raphael, Dynes, James, Eilemann, Stefan, Gal, Eyal, Gevaert, Michael Emiel, Ghobril, Jean-Pierre, Gidon, Albert, Graham, Joe W., Gupta, Anirudh, Haenel, Valentin, Hay, Etay, Heinis, Thomas, Hernando, Juan B., Hines, Michael, Kanari, Lida, Keller, Daniel, Kenyon, John, Khazen, Georges, Kim, Yihwa, King, James G., Kisvarday, Zoltan, Kumbhar, Pramod, Lasserre, Sébastien, Le Bé, Jean-Vincent, Magalhães, Bruno R.C., Merchán-Pérez, Angel, Meystre, Julie, Morrice, Benjamin Roy, Muller, Jeffrey, Muñoz-Céspedes, Alberto, Muralidhar, Shruti, Muthurasa, Keerthan, Nachbaur, Daniel, Newton, Taylor H., Nolte, Max, Ovcharenko, Aleksandr, Palacios, Juan, Pastor, Luis, Perin, Rodrigo, Ranjan, Rajnish, Riachi, Imad, Rodríguez, José-Rodrigo, Riquelme, Juan Luis, Rössert, Christian, Sfyrakis, Konstantinos, Shi, Ying, Shillcock, Julian C., Silberberg, Gilad, Silva, Ricardo, Tauheed, Farhan, Telefont, Martin, Toledo-Rodriguez, Maria, Tränkler, Thomas, Van Geit, Werner, Díaz, Jafet Villafranca, Walker, Richard, Wang, Yun, Zaninetta, Stefano M., DeFelipe, Javier, Hill, Sean L., Segev, Idan, Schürmann, Felix

“…We present a first-draft digital reconstruction of the microcircuitry of somatosensory cortex of juvenile rat. The reconstruction uses cellular and synaptic…”
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Digital Reconstruction of the Neuro-Glia-Vascular Architecture by Zisis, Eleftherios, Keller, Daniel, Kanari, Lida, Arnaudon, Alexis, Gevaert, Michael, Delemontex, Thomas, Coste, Benoît, Foni, Alessandro, Abdellah, Marwan, Calì, Corrado, Hess, Kathryn, Magistretti, Pierre Julius, Schürmann, Felix, Markram, Henry

“…Abstract Astrocytes connect the vasculature to neurons mediating the supply of nutrients and biochemicals. They are involved in a growing number of…”
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Representing stimulus information in an energy metabolism pathway by Coggan, Jay S., Keller, Daniel, Markram, Henry, Schürmann, Felix, Magistretti, Pierre J.

“…[Display omitted] •A metabolic pathway may code stimulus information to affect cellular function.•Simulation suggests new design possibilities for synthetic…”
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The physiological variability of channel density in hippocampal CA1 pyramidal cells and interneurons explored using a unified data-driven modeling workflow by Migliore, Rosanna, Lupascu, Carmen A, Bologna, Luca L, Romani, Armando, Courcol, Jean-Denis, Antonel, Stefano, Van Geit, Werner A H, Thomson, Alex M, Mercer, Audrey, Lange, Sigrun, Falck, Joanne, Rössert, Christian A, Shi, Ying, Hagens, Olivier, Pezzoli, Maurizio, Freund, Tamas F, Kali, Szabolcs, Muller, Eilif B, Schürmann, Felix, Markram, Henry, Migliore, Michele

“…Every neuron is part of a network, exerting its function by transforming multiple spatiotemporal synaptic input patterns into a single spiking output. This…”
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Online interoperable resources for building hippocampal neuron models via the Hippocampus Hub by Bologna, Luca Leonardo, Tocco, Antonino, Smiriglia, Roberto, Romani, Armando, Schürmann, Felix, Migliore, Michele

“…To build biophysically detailed models of brain cells, circuits, and regions, a data-driven approach is increasingly being adopted. This helps to obtain a…”
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EBRAINS Live Papers - Interactive Resource Sheets for Computational Studies in Neuroscience by Appukuttan, Shailesh, Bologna, Luca L., Schürmann, Felix, Migliore, Michele, Davison, Andrew P.

“…We present here an online platform for sharing resources underlying publications in neuroscience. It enables authors to easily upload and distribute digital…”
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Reconstruction and visualization of large-scale volumetric models of neocortical circuits for physically-plausible in silico optical studies by Abdellah, Marwan, Hernando, Juan, Antille, Nicolas, Eilemann, Stefan, Markram, Henry, Schürmann, Felix

“…We present a software workflow capable of building large scale, highly detailed and realistic volumetric models of neocortical circuits from the morphological…”
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An efficient analytical reduction of detailed nonlinear neuron models by Amsalem, Oren, Eyal, Guy, Rogozinski, Noa, Gevaert, Michael, Kumbhar, Pramod, Schürmann, Felix, Segev, Idan

“…Detailed conductance-based nonlinear neuron models consisting of thousands of synapses are key for understanding of the computational properties of single…”
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