Search Results - "Schurigt, U"

Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice by Sevenich, L, Werner, F, Gajda, M, Schurigt, U, Sieber, C, Müller, S, Follo, M, Peters, C, Reinheckel, T

“…Elevated expression of the cysteine protease cathepsin B (CTSB) has been correlated with a poor prognosis for cancer patients. In order to model high CTSB…”
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Relative contribution of matrix metalloprotease and cysteine protease activities to cytokine-stimulated articular cartilage degradation by Sondergaard, B.C., Henriksen, K., Wulf, H., Oestergaard, S., Schurigt, U., Bräuer, R., Danielsen, I., Christiansen, C., Qvist, P., Karsdal, M.A.

“…Both matrix metalloprotease (MMP) activity and cathepsin K (CK) activity have been implicated in cartilage turnover. We investigated the relative contribution…”
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Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice by Vasiljeva, O, Korovin, M, Gajda, M, Brodoefel, H, Bojic̆, L, Krüger, A, Schurigt, U, Sevenich, L, Turk, B, Peters, C, Reinheckel, T

“…Expression levels of the papain-like cysteine protease cathepsin B (Ctsb) have been positively correlated with mammary tumour progression and metastasis;…”
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The expression and localization of somatostatin receptors in dorsal root ganglion neurons of normal and monoarthritic rats by Bär, K.-J, Schurigt, U, Scholze, A, Segond Von Banchet, G, Stopfel, N, Bräuer, R, Halbhuber, K.-J, Schaible, H.-G

“…Somatostatin has antinociceptive effects by acting on somatostatin (sst) receptors in primary afferent neurons. Five sst receptor subtypes (sst 1–5) have been…”
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Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritis by Schurigt, Uta, Stopfel, Nadine, Hückel, Marion, Pfirschke, Christina, Wiederanders, Bernd, Bräuer, Rolf

“…Cartilage and bone degradation, observed in human rheumatoid arthritis (RA), are caused by aberrant expression of proteinases, resulting in an imbalance of…”
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Attenuation of murine antigen-induced arthritis by treatment with a decoy oligodeoxynucleotide inhibiting signal transducer and activator of transcription-1 (STAT-1) by Hückel, Marion, Schurigt, Uta, Wagner, Andreas H, Stöckigt, Renate, Petrow, Peter K, Thoss, Klaus, Gajda, Mieczyslaw, Henzgen, Steffen, Hecker, Markus, Bräuer, Rolf

“…The transcription factor STAT-1 (signal transducer and activator of transcription-1) plays a pivotal role in the expression of inflammatory gene products…”
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