Search Results - "Schuppe, Hans‐Christian"

Infectious, inflammatory and ‘autoimmune’ male factor infertility: how do rodent models inform clinical practice? by Fijak, Monika, Pilatz, Adrian, Hedger, Mark P, Nicolas, Nour, Bhushan, Sudhanshu, Michel, Vera, Tung, Kenneth S K, Schuppe, Hans-Christian, Meinhardt, Andreas

“…Abstract BACKGROUND Infection and inflammation of the reproductive tract are significant causes of male factor infertility. Ascending infections caused by…”
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Acute orchitis deciphered: Coxsackievirus B strains are the main etiology and their presence in semen is associated with acute inflammation and risk of persistent oligozoospermia by Pilatz, Adrian, Arneth, Borros, Kaiser, Rolf, Heger, Eva, Pirkl, Martin, Böttcher, Sindy, Fritzenwanker, Moritz, Renz, Harald, Mankertz, Annette, Schuppe, Hans‐Christian, Wagenlehner, Florian

“…Although various viruses are considered to be the clinical cause for acute orchitis, it is completely unclear to what extent and which viruses are…”
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Therapeutic options in male genital tract inflammation by Haidl, Gerhard, Haidl, Friederike, Allam, Jean‐Pierre, Schuppe, Hans‐Christian

“…Chronic inflammatory conditions of the genital tract are still unsatisfactorily recognised in the workup of male infertility due to inappropriate definitions…”
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Post‐prostatic‐massage urine exosomes of men with chronic prostatitis/chronic pelvic pain syndrome carry prostate‐cancer‐typical microRNAs and activate proto‐oncogenes by Schneider, Laura, Dansranjav, Temuujin, Neumann, Elena, Yan, Hang, Pilatz, Adrian, Schuppe, Hans‐Christian, Wagenlehner, Florian, Schagdarsurengin, Undraga

“…Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) has a high prevalence of up to 15% and accounts for 90–95% of prostatitis diagnoses, and yet its…”
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Comprehensive evaluation of hematospermia in patients with acute epididymitis compared to patients with isolated hematospermia by Dittmar, Florian, Rosellen, Jens, Reiser, Leo, Fritzenwanker, Moritz, Hauptmann, Arne, Diemer, Thorsten, Schuppe, Hans‐Christian, Wagenlehner, Florian, Pilatz, Adrian

“…Background Among the most commonly known causes of hematospermia are infections in the genitourinary tract, but no study exists that has comprehensively…”
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Acute Epididymitis Revisited: Impact of Molecular Diagnostics on Etiology and Contemporary Guideline Recommendations by Pilatz, Adrian, Hossain, Hamid, Kaiser, Rolf, Mankertz, Annette, Schüttler, Christian G, Domann, Eugen, Schuppe, Hans-Christian, Chakraborty, Trinad, Weidner, Wolfgang, Wagenlehner, Florian

“…Abstract Background Acute epididymitis is a common infectious disease of unknown etiology in about 30% of cases with guidelines based on studies published >15…”
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Zum 90. Geburtstag von Prof. Dr. med. Norbert Hofmann by Schuppe, Hans‐Christian

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Determination of leucocyte extracellular traps (ETs) in seminal fluid (ex vivo) in infertile patients—A pilot study by Schulz, Mabel, Zambrano, Fabiola, Schuppe, Hans‐Christian, Wagenlehner, Florian, Taubert, Anja, Ulrich, Gärtner, Sánchez, Raúl, Hermosilla, Carlos

“…Leucocytospermia has been associated with loss of sperm function. Extracellular traps (ETs) of leucocytes are produced during innate immune response. ETs can…”
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Increase of leucocyte-derived extracellular traps (ETs) in semen samples from human acute epididymitis patients—a pilot study by Zambrano, Fabiola, Schulz, Mabel, Pilatz, Adrian, Wagenlehner, Florian, Schuppe, Hans-Christian, Conejeros, Ivan, Uribe, Pamela, Taubert, Anja, Sánchez, Raúl, Hermosilla, Carlos

“…Purpose To study the effector mechanism against pathogens of polymorphonuclear neutrophils (PMN) and macrophages, called ETosis, involving the release of…”
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Chronic Prostatitis/Chronic Pelvic Pain Syndrome Leads to Impaired Semen Parameters, Increased Sperm DNA Fragmentation and Unfavorable Changes of Sperm Protamine mRNA Ratio by Berg, Elena, Houska, Petr, Nesheim, Nils, Schuppe, Hans-Christian, Pilatz, Adrian, Fijak, Monika, Manthey, Marc, Steger, Klaus, Wagenlehner, Florian, Schagdarsurengin, Undraga

“…Background: Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a frequent disease affecting men of every age and accounting for a great number of…”
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Testicular activin and follistatin levels are elevated during the course of experimental autoimmune epididymo–orchitis in mice by Nicolas, Nour, Michel, Vera, Bhushan, Sudhanshu, Wahle, Eva, Hayward, Susan, Ludlow, Helen, de Kretser, David M., Loveland, Kate L., Schuppe, Hans-Christian, Meinhardt, Andreas, Hedger, Mark P., Fijak, Monika

“…Experimental autoimmune epididymo-orchitis (EAEO) is a model of chronic inflammation, induced by immunisation with testicular antigens, which reproduces the…”
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Proteomic biomarkers in seminal plasma as predictors of reproductive potential in azoospermic men by Fietz, Daniela, Sgaier, Raouda, O'Donnell, Liza, Stanton, Peter G, Dagley, Laura F, Webb, Andrew I, Schuppe, Hans-Christian, Diemer, Thorsten, Pilatz, Adrian

“…Azoospermia, characterized by an absence of sperm in the ejaculate, represents the most severe form of male infertility. While surgical sperm retrieval in…”
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High prevalence of urogenital infection/inflammation in patients with azoospermia does not impede surgical sperm retrieval by Pilatz, Adrian, Kilb, Jill, Kaplan, Huelya, Fietz, Daniela, Hossain, Hamid, Schüttler, Christian G., Diemer, Thorsten, Bergmann, Martin, Domann, Eugen, Weidner, Wolfgang, Wagenlehner, Florian, Schuppe, Hans-Christian

“…Considering infection/inflammation to be an important risk factor in male infertility, the aim of this study was to make a comprehensive evaluation of the…”
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The conserved genetic program of male germ cells uncovers ancient regulators of human spermatogenesis by Brattig-Correia, Rion, Almeida, Joana M, Wyrwoll, Margot Julia, Julca, Irene, Sobral, Daniel, Misra, Chandra Shekhar, Di Persio, Sara, Guilgur, Leonardo Gastón, Schuppe, Hans-Christian, Silva, Neide, Prudêncio, Pedro, Nóvoa, Ana, Leocádio, Ana S, Bom, Joana, Laurentino, Sandra, Mallo, Moises, Kliesch, Sabine, Mutwil, Marek, Rocha, Luis M, Tüttelmann, Frank, Becker, Jörg D, Navarro-Costa, Paulo

“…Male germ cells share a common origin across animal species, therefore they likely retain a conserved genetic program that defines their cellular identity…”
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Prospective evaluation of scrotal ultrasound and intratesticular perfusion by color-coded duplex sonography (CCDS) in TESE patients with azoospermia by Altinkilic, Bora, Pilatz, Adrian, Diemer, Thorsten, Wolf, Julia, Bergmann, Martin, Schönbrunn, Sarah, Ligges, Uwe, Schuppe, Hans-Christian, Weidner, Wolfgang

“…Purpose The objective of this study was to assess whether CCDS might improve the outcome of testicular sperm retrieval in patients with azoospermia…”
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High levels of oxysterol sulfates in serum of patients with steroid sulfatase deficiency[S] by Sánchez-Guijo, Alberto, Oji, Vinzenz, Hartmann, Michaela F., Schuppe, Hans-Christian, Traupe, Heiko, Wudy, Stefan A.

“…Steroid sulfatase (STS) deficiency is the underlying cause of the skin condition known as recessive X-linked ichthyosis (RXLI). RXLI patients show scales on…”
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Expression of ciliated bronchial epithelium 1 during human spermatogenesis by Pleuger, Christiane, M.Sc, Fietz, Daniela, Dr.Med.Vet, Hartmann, Katja, Dr.Med.Vet, Schuppe, Hans-Christian, Dr.Med, Weidner, Wolfgang, Dr.Med, Kliesch, Sabine, Dr.Med, Baker, Mark, Ph.D, O'Bryan, Moira K., Ph.D, Bergmann, Martin, Dr.Rer.Medic

“…Objective To define the precise cellular localization of ciliated bronchial epithelium 1 (CBE1) in the human testis and test its relationship to impaired…”
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Excessive unilateral proliferation of spermatogonia in a patient with non-obstructive azoospermia - adverse effect of clomiphene citrate pre-treatment? by Fietz, Daniela, Pilatz, Adrian, Diemer, Thorsten, Wagenlehner, Florian, Bergmann, Martin, Schuppe, Hans-Christian

“…Clomiphene citrate has been proposed as pre-treatment for infertile men with non-obstructive, testicular azoospermia (NOA) before surgery for testicular sperm…”
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Cytokines in Male Fertility and Reproductive Pathologies: Immunoregulation and Beyond by Loveland, Kate L, Klein, Britta, Pueschl, Dana, Indumathy, Sivanjah, Bergmann, Martin, Loveland, Bruce E, Hedger, Mark P, Schuppe, Hans-Christian

“…Germline development is dependent on the environment formed by somatic cells and the differentiation cues they provide; hence, the impact of local factors is…”
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Acute epididymitis induces alterations in sperm protein composition by Pilatz, Adrian, M.D, Lochnit, Guenter, Ph.D, Karnati, Srikanth, Ph.D, Paradowska-Dogan, Agnieszka, Ph.D, Lang, Tali, Ph.D, Schultheiss, Dirk, M.D, Schuppe, Hans-Christian, M.D, Hossain, Hamid, M.D, Baumgart-Vogt, Eveline, Ph.D, Weidner, Wolfgang, M.D, Wagenlehner, Florian, M.D

“…Objective To use a proteomic approach to evaluate possible postinflammatory alterations in the protein composition of motile sperm in patients 3 months after…”
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