Search Results - "Schumann, Pascale"

Post‐stroke depression: mechanisms, translation and therapy by Loubinoux, Isabelle, Kronenberg, Golo, Endres, Matthias, Schumann‐Bard, Pascale, Freret, Thomas, Filipkowski, Robert K., Kaczmarek, Leszek, Popa‐Wagner, Aurel

“…The interaction between depression and stroke is highly complex. Post‐stroke depression (PSD) is among the most frequent neuropsychiatric consequences of…”
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Object recognition test in mice by Leger, Marianne, Quiedeville, Anne, Bouet, Valentine, Haelewyn, Benoît, Boulouard, Michel, Schumann-Bard, Pascale, Freret, Thomas

“…The object recognition test is now among the most commonly used behavioral tests for mice. A mouse is presented with two similar objects during the first…”
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Mechanisms underlying the neuroprotective effect of brain reserve against late life depression by Freret, Thomas, Gaudreau, Pierrette, Schumann-Bard, Pascale, Billard, Jean-Marie, Popa-Wagner, Aurel

“…Depression is common and medically relevant illness that has been associated to a state of “accelerated aging” and can significantly compromise successful…”
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Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouse by Bouët, Valentine, Freret, Thomas, Toutain, Jérôme, Divoux, Didier, Boulouard, Michel, Schumann-Bard, Pascale

“…Whereas behavioral impairments after stroke are increasingly studied in the rat, little is known about the long-term functional consequences of focal ischemia…”
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Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat by Freret, Thomas, Valable, Samuel, Chazalviel, Laurent, Saulnier, Romaric, Mackenzie, Eric T., Petit, Edwige, Bernaudin, Myriam, Boulouard, Michel, Schumann-Bard, Pascale

“…The mechanisms underlying functional recovery after stroke are poorly understood. Brain‐adaptive responses to the hypoxic stress elicited by ischemia could…”
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Genetic Background Influence on Hippocampal Synaptic Plasticity: Frequency-Dependent Variations between an Inbred and an Outbred Mice Strain by Roux, Candice M, Lecouflet, Pierre, Billard, Jean-Marie, Esneault, Elise, Leger, Marianne, Schumann-Bard, Pascale, Freret, Thomas

“…For almost half a century, acute hippocampal slice preparations have been widely used to investigate anti-amnesic (or promnesic) properties of drug candidates…”
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Behavioral Deficits After Distal Focal Cerebral Ischemia in Mice: Usefulness of Adhesive Removal Test by Freret, Thomas, Bouet, Valentine, Leconte, Claire, Roussel, Simon, Chazalviel, Laurent, Divoux, Didier, Schumann-Bard, Pascale, Boulouard, Michel

“…Distal occlusion of the middle cerebral artery (dMCAo), which closely mimics human stroke, is one of the most used animal models. However, although assessment…”
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Environmental enrichment enhances episodic-like memory in association with a modified neuronal activation profile in adult mice by Leger, Marianne, Quiedeville, Anne, Paizanis, Eleni, Natkunarajah, Sharuja, Freret, Thomas, Boulouard, Michel, Schumann-Bard, Pascale

“…Although environmental enrichment is well known to improve learning and memory in rodents, the underlying neuronal networks' plasticity remains poorly…”
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Effects of chronic tramadol administration on cognitive flexibility in mice by Attoh-Mensah, Elpidio, Léger, Marianne, Loggia, Gilles, Fréret, Thomas, Chavoix, Chantal, Schumann-Bard, Pascale

“…Rationale Tramadol is widely used for pain relief especially in seniors. However, long-term use of tramadol has serious adverse effects, including cognitive…”
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Spatial memory deficit across aging: current insights of the role of 5-HT7 receptors by Beaudet, Gregory, Bouet, Valentine, Jozet-Alves, Christelle, Schumann-Bard, Pascale, Dauphin, François, Paizanis, Eleni, Boulouard, Michel, Freret, Thomas

“…Elderly persons often face biological, psychological or social changes over time that may cause discomfort or morbidity. While some cognitive domains remain…”
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Effect of hypoxic preconditioning on brain genomic response before and following ischemia in the adult mouse: Identification of potential neuroprotective candidates for stroke by Tang, Yang, Pacary, Emilie, Fréret, Thomas, Divoux, Didier, Petit, Edwige, Schumann-Bard, Pascale, Bernaudin, Myriam

“…The aim of the present study is to better understand oxygen-sensitive adaptative pathways underlying the hypoxic preconditioning-induced protection of the…”
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Combined therapeutic strategy using erythropoietin and mesenchymal stem cells potentiates neurogenesis after transient focal cerebral ischemia in rats by Esneault, Elise, Pacary, Emilie, Eddi, Dauphou, Freret, Thomas, Tixier, Emmanuelle, Toutain, Jérôme, Touzani, Omar, Schumann-Bard, Pascale, Petit, Edwige, Roussel, Simon, Bernaudin, Myriam

“…Many studies showed beneficial effects of either erythropoietin (EPO) or mesenchymal stem cells (MSCs) treatment in cerebral ischemia. In addition to a…”
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Intraluminal thread model of focal stroke in the non-human primate by Freret, Thomas, Bouet, Valentine, Toutain, Jérôme, Saulnier, Romaric, Pro-Sistiaga, Palma, Bihel, Ebeline, MacKenzie, Eric T, Roussel, Simon, Schumann-Bard, Pascale, Touzani, Omar

“…The common marmoset (Callithrix jacchus), a New World monkey, has recently been used as a model of focal cerebral ischaemia. Here, we sought to develop a…”
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Inhibition of neuronal nitric oxide synthase by 7-methoxyindazole and related substituted indazoles by Schumann, Pascale, Collot, Valérie, Hommet, Yannick, Gsell, Willy, Dauphin, François, Sopkova, Jana, MacKenzie, Eric T, Duval, Dominique, Boulouard, Michel, Rault, Sylvain

“…The synthesis and pharmacological evaluation of methoxyindazoles as new inhibitors of neuronal nitric oxide synthase are presented. The 7-methoxyindazole,…”
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Time-course of age-related temporal order memory decline in an object recognition paradigm in mice by Belblidia, Hassina, Freret, Thomas, Leger, Marianne, Schumann-Bard, Pascale

“…Temporal order memory refers to the ability to remember the order of occurrence of items across time. It is a critical feature of episodic memory that is often…”
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The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice by Freret, Thomas, Bouet, Valentine, Boulouard, Michel, Toutain, Jérôme, Divoux, Didier, Bernaudin, Myriam, Schumann-Bard, Pascale

“…Long-term functional deficits after a brain injury are difficult to assess in the mouse. If no deficit is observed, researchers could conclude either that the…”
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Environmental Enrichment Duration Differentially Affects Behavior and Neuroplasticity in Adult Mice by Leger, Marianne, Paizanis, Eleni, Dzahini, Kwamivi, Quiedeville, Anne, Bouet, Valentine, Cassel, Jean-Christophe, Freret, Thomas, Schumann-Bard, Pascale, Boulouard, Michel

“…Environmental enrichment is a powerful way to stimulate brain and behavioral plasticity. However the required exposure duration to reach such changes has not…”
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Long-Term Music Exposure Prevents Age-Related Cognitive Deficits in Rats Independently of Hippocampal Neurogenesis by Rizzolo, Lou, Leger, Marianne, Corvaisier, Sophie, Groussard, Mathilde, Platel, Hervé, Bouet, Valentine, Schumann-Bard, Pascale, Freret, Thomas

“…Abstract Cognitive decline appears across aging. While some studies report beneficial effects of musical listening and practice on cognitive aging, the…”
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Adverse Effects of Anticholinergic Drugs on Cognition and Mobility: Cutoff for Impairment in a Cross-Sectional Study in Young–Old and Old–Old Adults by Attoh-Mensah, Elpidio, Loggia, Gilles, Schumann-Bard, Pascale, Morello, Rémy, Descatoire, Pablo, Marcelli, Christian, Chavoix, Chantal

“…Background Drugs with anticholinergic properties are commonly prescribed in older adults despite growing evidence of their adverse outcomes. Several issues…”
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Interplay between 5-HT4 Receptors and GABAergic System within CA1 Hippocampal Synaptic Plasticity by Lecouflet, Pierre, Roux, Candice M, Potier, Brigitte, Leger, Marianne, Brunet, Elie, Billard, Jean-Marie, Schumann-Bard, Pascale, Freret, Thomas

“…Abstract The type 4 serotonin receptor (5-HT4R) is highly involved in cognitive processes such as learning and memory. Behavioral studies have shown a…”
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