Search Results - "Schumann, Michael"

Human biomonitoring (HBM)-II values for perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) - Description, derivation and discussion by Schümann, Michael, Lilienthal, Hellmuth, Hölzer, Jürgen

“…For evaluation of internal exposure to harmful substances, the Human Biomonitoring Commission of the German Environment Agency (HBM Commission) develops…”
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Gluten-Free Diet in Celiac Disease-Forever and for All? by Itzlinger, Alice, Branchi, Federica, Elli, Luca, Schumann, Michael

“…The gluten-free diet is the only effective treatment available for celiac disease. However, it is difficult to adhere to and a closer look on the diet's…”
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Spectrum of gluten-related disorders: consensus on new nomenclature and classification by Sapone, Anna, Bai, Julio C, Ciacci, Carolina, Dolinsek, Jernej, Green, Peter H R, Hadjivassiliou, Marios, Kaukinen, Katri, Rostami, Kamran, Sanders, David S, Schumann, Michael, Ullrich, Reiner, Villalta, Danilo, Volta, Umberto, Catassi, Carlo, Fasano, Alessio

“…A decade ago celiac disease was considered extremely rare outside Europe and, therefore, was almost completely ignored by health care professionals. In only 10…”
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Monocyte and M1 Macrophage-induced Barrier Defect Contributes to Chronic Intestinal Inflammation in IBD by Lissner, Donata, Schumann, Michael, Batra, Arvind, Kredel, Lea-Isabel, Kühl, Anja A, Erben, Ulrike, May, Claudia, Schulzke, Jörg-Dieter, Siegmund, Britta

“…Macrophages are key players in inflammatory bowel diseases (IBD). This study aimed to determine site-specific effects of defined macrophage subtypes on the…”
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Intestinal Barrier Function in Gluten-Related Disorders by Cardoso-Silva, Danielle, Delbue, Deborah, Itzlinger, Alice, Moerkens, Renée, Withoff, Sebo, Branchi, Federica, Schumann, Michael

“…Gluten-related disorders include distinct disease entities, namely celiac disease, wheat-associated allergy and non-celiac gluten/wheat sensitivity. Despite…”
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Nano- and microscaled particles for drug targeting to inflamed intestinal mucosa—A first in vivo study in human patients by Schmidt, Carsten, Lautenschlaeger, Christian, Collnot, Eva-Maria, Schumann, Michael, Bojarski, Christian, Schulzke, Jörg-Dieter, Lehr, Claus-Michael, Stallmach, Andreas

“…Most of the drugs used in the treatment of inflammatory bowel disease (IBD) become systemically bioavailable and potentially bear strong adverse effects…”
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Celiac Disease: Role of the Epithelial Barrier by Schumann, Michael, Siegmund, Britta, Schulzke, Jörg D, Fromm, Michael

“…In celiac disease (CD) a T-cell–mediated response to gluten is mounted in genetically predisposed individuals, resulting in a malabsorptive enteropathy…”
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Splicing-accessible coding 3′UTRs control protein stability and interaction networks by Preussner, Marco, Gao, Qingsong, Morrison, Eliot, Herdt, Olga, Finkernagel, Florian, Schumann, Michael, Krause, Eberhard, Freund, Christian, Chen, Wei, Heyd, Florian

“…Abstract Background 3′-Untranslated regions (3′UTRs) play crucial roles in mRNA metabolism, such as by controlling mRNA stability, translation efficiency, and…”
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Epithelial Tight Junctions in Intestinal Inflammation by Schulzke, Joerg D., Ploeger, Svenja, Amasheh, Maren, Fromm, Anja, Zeissig, Sebastian, Troeger, Hanno, Richter, Jan, Bojarski, Christian, Schumann, Michael, Fromm, Michael

“…The epithelium in inflamed intestinal segments of patients with Crohn's disease is characterized by a reduction of tight junction strands, strand breaks, and…”
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Non-Celiac Gluten sensitivity: the new frontier of gluten related disorders by Catassi, Carlo, Bai, Julio C, Bonaz, Bruno, Bouma, Gerd, Calabrò, Antonio, Carroccio, Antonio, Castillejo, Gemma, Ciacci, Carolina, Cristofori, Fernanda, Dolinsek, Jernej, Francavilla, Ruggiero, Elli, Luca, Green, Peter, Holtmeier, Wolfgang, Koehler, Peter, Koletzko, Sibylle, Meinhold, Christof, Sanders, David, Schumann, Michael, Schuppan, Detlef, Ullrich, Reiner, Vécsei, Andreas, Volta, Umberto, Zevallos, Victor, Sapone, Anna, Fasano, Alessio

“…Non Celiac Gluten sensitivity (NCGS) was originally described in the 1980s and recently a "re-discovered" disorder characterized by intestinal and…”
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Analysis of Circulating Food Antigen-Specific T-Cells in Celiac Disease and Inflammatory Bowel Disease by Rodríguez-Sillke, Yasmina, Schumann, Michael, Lissner, Donata, Branchi, Federica, Proft, Fabian, Steinhoff, Ulrich, Siegmund, Britta, Glauben, Rainer

“…To demonstrate and analyze the specific T-cell response following barrier disruption and antigen translocation, circulating food antigen-specific effector…”
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Celiac Disease Monocytes Induce a Barrier Defect in Intestinal Epithelial Cells by Delbue, Deborah, Cardoso-Silva, Danielle, Branchi, Federica, Itzlinger, Alice, Letizia, Marilena, Siegmund, Britta, Schumann, Michael

“…Intestinal epithelial barrier function in celiac disease (CeD) patients is altered. However, the mechanism underlying this effect is not fully understood. The…”
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Portal hypertension in common variable immunodeficiency disorders - a single center analysis on clinical and immunological parameter in 196 patients by Hanitsch, Leif G, Steiner, Sophie, Schumann, Michael, Wittke, Kirsten, Kedor, Claudia, Scheibenbogen, Carmen, Fischer, Andreas

“…Liver manifestations and in particular portal hypertension (PH) contribute significantly to morbidity and mortality of patients with common variable…”
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Chemokine Transfer by Liver Sinusoidal Endothelial Cells Contributes to the Recruitment of CD4+ T Cells into the Murine Liver by Neumann, Katrin, Erben, Ulrike, Kruse, Nils, Wechsung, Katja, Schumann, Michael, Klugewitz, Katja, Scheffold, Alexander, Kühl, Anja A

“…Leukocyte adhesion and transmigration are central features governing immune surveillance and inflammatory reactions in body tissues. Within the liver…”
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Follow-Up of Celiac Disease in Adults: "When, What, Who, and Where" by Mulder, Chris J J, Elli, Luca, Lebwohl, Benjamin, Makharia, Govind K, Rostami, Kamran, Rubio-Tapia, Alberto, Schumann, Michael, Tye-Din, Jason, Zeitz, Jonas, Al-Toma, Abdulbaqi

“…For patients with celiac disease (CeD), a lifelong gluten-free diet is not a voluntary lifestyle choice-it is a necessity. The key end points in clinical…”
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Uptake of Tropheryma whipplei by Intestinal Epithelia by Friebel, Julian, Schinnerling, Katina, Weigt, Kathleen, Heldt, Claudia, Fromm, Anja, Bojarski, Christian, Siegmund, Britta, Epple, Hans-Jörg, Kikhney, Judith, Moter, Annette, Schneider, Thomas, Schulzke, Jörg D, Moos, Verena, Schumann, Michael

“…( ) can cause different pathologies, e.g., Whipple's disease and transient gastroenteritis. The mechanism by which the bacteria pass the intestinal epithelial…”
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A novel method for imaging sites of paracellular passage of macromolecules in epithelial sheets by Richter, Jan F., Schmauder, Ralf, Krug, Susanne M., Gebert, Andreas, Schumann, Michael

“…Understanding the dynamics of intestinal barrier function is key to elucidating oral delivery routes of therapeutics as well as to understanding various…”
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Proteolytic Activity of the Paracaspase MALT1 Is Involved in Epithelial Restitution and Mucosal Healing by Wittner, Leonie, Wagener, Lukas, Wiese, Jakob J, Stolzer, Iris, Krug, Susanne M, Naschberger, Elisabeth, Jackstadt, Rene, Beyaert, Rudi, Atreya, Raja, Kühl, Anja A, Sturm, Gregor, Gonzalez-Acera, Miguel, Patankar, Jay V, Becker, Christoph, Siegmund, Britta, Trajanoski, Zlatko, Winner, Beate, Neurath, Markus F, Schumann, Michael, Günther, Claudia

“…The paracaspase MALT1 is a crucial regulator of immune responses in various cellular contexts. Recently, there is increasing evidence suggesting that MALT1…”
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Escherichia coli Alpha-Hemolysin HlyA Induces Host Cell Polarity Changes, Epithelial Barrier Dysfunction and Cell Detachment in Human Colon Carcinoma Caco-2 Cell Model via PTEN-Dependent Dysregulation of Cell Junctions by Schulz, Emanuel, Schumann, Michael, Schneemann, Martina, Dony, Violaine, Fromm, Anja, Nagel, Oliver, Schulzke, Jörg-Dieter, Bücker, Roland

“…( ) of the B2 phylotype reside in human and animal intestines. The bacteria possess pathogenicity factors such as α-hemolysin (HlyA) that can induce intestinal…”
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Recombinant Marburg Virus Expressing EGFP Allows Rapid Screening of Virus Growth and Real-time Visualization of Virus Spread by Schmidt, Kristina Maria, Schümann, Michael, Olejnik, Judith, Krähling, Verena, Mühlberger, Elke

“…The generation of recombinant enhanced green fluorescent protein (EGFP)-expressing viruses has significantly improved the study of their life cycle and opened…”
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