Search Results - "Schumacher, L B"

A model of synovial fluid lubricant composition in normal and injured joints by Blewis, M E, Nugent-Derfus, G E, Schmidt, T A, Schumacher, B L, Sah, R L

“…The synovial fluid (SF) of joints normally functions as a biological lubricant, providing low-friction and low-wear properties to articulating cartilage…”
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Tissue engineering of stratified articular cartilage from chondrocyte subpopulations by Klein, T.J., Schumacher, B.L., Schmidt, T.A., Li, K.W., Voegtline, M.S., Masuda, K., Thonar, E.J.-M.A., Sah, R.L.

“…Objective: To test if subpopulations of chondrocytes from different cartilage zones could be used to engineer cartilage constructs with features of normal…”
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Immunodetection and partial cDNA sequence of the proteoglycan, superficial zone protein, synthesized by cells lining synovial joints by Schumacher, B L, Hughes, C E, Kuettner, K E, Caterson, B, Aydelotte, M B

“…We have previously described a large proteoglycan named superficial zone protein that was isolated and purified from culture medium of superficial slices of…”
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PRG4 exchange between the articular cartilage surface and synovial fluid by Nugent-Derfus, G.E., Chan, A.H., Schumacher, B.L., Sah, R.L.

“…The boundary lubrication function of articular cartilage is mediated in part by proteoglycan 4 (PRG4) molecules, found both in synovial fluid (SF) and bound to…”
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Indentation probing of human articular cartilage: Effect on chondrocyte viability by Bae, W.C., Ph.D, Schumacher, B.L., B.S, Sah, R.L., M.D., Sc.D

“…Summary Background Clinical arthroscopic probes based on indentation testing are being developed. However, the biological effects of certain design parameters…”
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Articular Cartilage Superficial Zone Protein (SZP) Is Homologous to Megakaryocyte Stimulating Factor Precursor and Is a Multifunctional Proteoglycan with Potential Growth-Promoting, Cytoprotective, and Lubricating Properties in Cartilage Metabolism by Flannery, Carl R., Hughes, Clare E., Schumacher, Barbara L., Tudor, Debbie, Aydelotte, Margaret B., Kuettner, Klaus E., Caterson, Bruce

“…We have performed cDNA sequencing and homology analyses to elucidate the complete amino acid composition for a superficial zone protein (SZP) from human and…”
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Static and dynamic compression regulate cartilage metabolism of PRoteoGlycan 4 (PRG4) by Nugent, G E, Schmidt, T A, Schumacher, B L, Voegtline, M S, Bae, W C, Jadin, K D, Sah, R L

“…The boundary lubrication function of articular cartilage is mediated in part by molecules at the articular surface and in synovial fluid, encoded by Prg4. The…”
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Glucose tolerance in pregnancy: ethnic variation and influence of body habitus by Green, J R, Pawson, I G, Schumacher, L B, Perry, J, Kretchmer, N

“…Little is known about ethnic differences in glucose tolerance during pregnancy. In this study we examined 3366 Hispanic, Chinese, black, and non-Hispanic white…”
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Influence of maternal body habitus and glucose tolerance on birth weight by Green, J R, Schumacher, L B, Pawson, I G, Partridge, J C, Kretchmer, N

“…Many physicians believe that macrosomia is a hallmark of a pregnancy complicated by glucose intolerance. Because the prevalence of obesity is increased among…”
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Human knee and ankle cartilage explants: catabolic differences by Eger, Wolfgang, Schumacher, Barbara L, Mollenhauer, Jürgen, Kuettner, Klaus E, Cole, Ada A

“…The prevalence of osteoarthritis (OA) is lower in some joints, i.e., the ankle, than in the knee. We have compared the cartilages from these two joints of the…”
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Growth of immigrant children in the newcomer schools of San Francisco by Schumacher, L.B, Pawson, I.G, Kretchmer, N

“…Extract: A semilongitudinal study on growth and development was initiated on immigrant and refugee school-aged children in San Francisco. Anthropometric values…”
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A novel proteoglycan synthesized and secreted by chondrocytes of the superficial zone of articular cartilage by Schumacher, B L, Block, J A, Schmid, T M, Aydelotte, M B, Kuettner, K E

“…A novel proteoglycan (PG) has been identified in culture medium from thin slices of the superficial zone of bovine articular cartilage. This PG is synthesized…”
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Synthesis and turnover of proteoglycans by human and bovine adult articular chondrocytes cultured in alginate beads by Häuselmann, H J, Aydelotte, M B, Schumacher, B L, Kuettner, K E, Gitelis, S H, Thonar, E J

“…Human and bovine adult articular chondrocytes cultured in alginate beads or agarose gel retain their spherical shape and typical chondrocytic appearance for at…”
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Upper Arm Anthropometric Characteristics of Immigrant Children in the Newcomer Schools of San Francisco by SCHUMACHER, LAURIE B., KRETCHMER, NORMAN

“…Upper arm anthropometrie measurements (mid-arm circumference, and triceps) were collected on newly arrived immigrant and refugee school-aged children in San…”
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Biological factors affecting intrauterine growth by Kretchmer, N, Schumacher, L B, Silliman, K

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Detection of superficial zone protein in human and animal body fluids by cross-species monoclonal antibodies specific to superficial zone protein by Su, J L, Schumacher, B L, Lindley, K M, Soloveychik, V, Burkhart, W, Triantafillou, J A, Kuettner, K, Schmid, T

“…In this report we describe the purification of human superficial zone protein (SZP), the generation of cross-species monoclonal antibodies (MAbs) and the…”
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Differential regulation of proteoglycan 4 metabolism in cartilage by IL-1α, IGF-I, and TGF-β1 by Schmidt, T.A., Ph.D, Gastelum, N.S., B.S, Han, E.H., M.S, Nugent-Derfus, G.E., Ph.D, Schumacher, B.L., B.S, Sah, R.L., M.D., Sc.D

“…Summary Objectives To determine (1) if interleukin-1 alpha (IL-1α), insulin like growth factor I (IGF-I), and transforming growth factor-beta 1 (TGF-β1)…”
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Expansion and redifferentiation of chondrocytes from osteoarthritic cartilage: cells for human cartilage tissue engineering by Hsieh-Bonassera, Nancy D, Wu, Iwen, Lin, Jonathan K, Schumacher, Barbara L, Chen, Albert C, Masuda, Koichi, Bugbee, William D, Sah, Robert L

“…To determine if selected culture conditions enhance the expansion and redifferentiation of chondrocytes isolated from human osteoarthritic cartilage with…”
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Interactive cytokine regulation of synoviocyte lubricant secretion by Blewis, Megan E, Lao, Brian J, Schumacher, Barbara L, Bugbee, William D, Sah, Robert L, Firestein, Gary S

“…Cytokine regulation of synovial fluid (SF) lubricants, hyaluronan (HA), and proteoglycan 4 (PRG4) is important in health, injury, and disease of synovial…”
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Smooth muscle cells produce an inhibitor of endothelial cell growth by Schumacher, B L, Grant, D, Eisenstein, R

“…A potent inhibitor of endothelial cell growth and neovascularization has previously been isolated from both bovine and human aorta. In an attempt to determine…”
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