Search Results - "Schulze, T.G"

S.21.01 The genetic foundation by Schulze, T.G

Get full text

Pharmacogenomic aspects of bipolar disorder: An update by Budde, M, Degner, D, Brockmöller, J, Schulze, T.G

“…Abstract The hopes for readily implementable precision medicine are high. For many complex disorders, such as bipolar disorder, these hopes critically hinge on…”
Get full text

AS23-04 - The phenotype - the still unknown quantity in psychiatric genetics? by Schulze, T.G

“…Research into the genetic basis of psychiatric disorders has reached a turning point. Genome-wide association studies (GWAS), encompassing several thousand…”
Get full text

ECP06-01 - Genomewide - asscociation studies of psychiatric phenotypes: What they have told us and what to do next by Schulze, T.G

“…Genome-wide association studies of psychiatric disorders have highlighted several novel susceptibility genes and taught us several importnat lessons…”
Get full text

Subtyping schizophrenia: A comparison of positive/negative and system-specific approaches by Lang, F.U, Walther, S, Stegmayer, K, Anderson-Schmidt, H, Schulze, T.G, Becker, T, Jäger, M

“…Abstract Background Schizophrenia is a heterogeneous disorder. Over the years, different approaches have been proposed to approach this heterogeneity by…”
Get full text

Doing research in the USA: Chances and challenges for young European psychiatrists by Schulze, T.G

Get full text

Beyond mania and depression: Neuropsychological correlates of the course of bipolar disorder by Budde, M, Heilbronner, U, Schulze, T.G

“…Besides the affective symptoms (manic and depressive ones), that characterize the clinical appearance of bipolar disorder (BD), patients usually suffer from…”
Get full text

An update from the Consortium on Lithium Genetics (ConLiGen): Phenomic and genomic studies by Heilbronner, U, Hou, L, Rietschel, M, McMahon, F.J, Schulze, T.G

“…While no genome-wide significant finding at the p<5*10-8 level was observed, the top hit SNP rs17728078 in the gene SLC4A10 (solute carrier family 4, sodium…”
Get full text

EPA-1747 – Investigation of the interplay between genetic and environmental risk factors for smoking behaviour by Strohmaier, J, Treutlein, J, Frank, J, Mühleisen, T, Degenhardt, F, Witt, S.H, Cichon, S, Schulze, T.G, Nöthen, M.M, Rietschel, M

“…Smoking-behaviour is influenced by environmental and genetic risk factors. Established epidemiological risk factors include early age at onset (AaO),…”
Get full text

EFFECTS OF INDOOR CYCLING ON HIPPOCAMPAL STRUCTURE, METABOLISM AND CLINICAL FEATURES OF SCHIZOPHRENIA by Falkai, Peter G, Malchow, B, Huber, J, Fleige, H, Gruber, O, Schulze, T.G, Schmitt, A, Honer, W.G, Keller, K

Get full text

Managing sensitive phenotypic data and biomaterial in longitudinal psychiatric genetic research projects: an IT tool box approach by Heilbronner, U, Demiroglu, S.Y, Skrowny, D, Quade, M, Schwanke, J, Budde, M, Gullatz, V, Reich-Erkelenz, D, Jakob, J.J, Falkai, P, Rienhoff, O, Helbing, K, Schulze, T.G

“…Core elements of such toolbox are a) the Phenotype tool, in which clinical data such as psychiatric rating scales and psychological tests are stored, b) the…”
Get full text

PW01-12 - Two or three age-of-onset groups in bipolar I disorder? Findings of commingling analysis in Romanian and German bipolar I patients by Grigoroiu-Serbanescu, M, Rietschel, M, Paul, T, Schulze, T.G, Noethen, M.M, Cichon, S, Elston, R.C

“…Background Age-of-onset (AO) seems to be a phenotypic variable with a strong genetic component and therefore useful in molecular analysis of bipolar disorder…”
Get full text

Association between completed suicide and bipolar disorder: A systematic review of the literature by Plans, L., Barrot, C., Nieto, E., Rios, J., Schulze, T.G., Papiol, S., Mitjans, M., Vieta, E., Benabarre, A.

“…•Bipolar disorder is associated with a high risk of suicide death.•Most people who commit suicide are psychiatric patients, most of whom have affective…”
Get full text

P.2.e.001 Social adjustment during childhood and adolescence: bipolar patients outperform healthy controls by Schulze, T.G, Georgi, A, Schmael, C, Schirmbeck, F, Strohmaier, J, Boesshenz, K.V, Nöthen, M.M, Rietschel, M

Get full text

Utility and accuracy of template-directed dye-terminator incorporation with fluorescence-polarization detection for genotyping single nucleotide polymorphisms by Akula, N, Chen, Y S, Hennessy, K, Schulze, T G, Singh, G, McMahon, F J

“…There are little independent data available about how well single nucleotide polymorphism (SNP) genotyping technologies perform in the typical molecular…”
Get full text

Kraepelin revisited: schizophrenia from degeneration to failed regeneration by Falkai, P, Rossner, M J, Schulze, T G, Hasan, A, Brzózka, M M, Malchow, B, Honer, W G, Schmitt, A

“…One hundred years after its conceptual definition as ‘Dementia Praecox’ by Emil Kraepelin, schizophrenia is still a serious psychiatric illness that affects…”
Get full text

Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder by Chen, D T, Jiang, X, Akula, N, Shugart, Y Y, Wendland, J R, Steele, C J M, Kassem, L, Park, J-H, Chatterjee, N, Jamain, S, Cheng, A, Leboyer, M, Muglia, P, Schulze, T G, Cichon, S, Nöthen, M M, Rietschel, M, McMahon, F J

“…Meta-analyses of bipolar disorder (BD) genome-wide association studies (GWAS) have identified several genome-wide significant signals in European-ancestry…”
Get full text

A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder by Baum, A E, Akula, N, Cabanero, M, Cardona, I, Corona, W, Klemens, B, Schulze, T G, Cichon, S, Rietschel, M, Nöthen, M M, Georgi, A, Schumacher, J, Schwarz, M, Abou Jamra, R, Höfels, S, Propping, P, Satagopan, J, Detera-Wadleigh, S D, Hardy, J, McMahon, F J

“…The genetic basis of bipolar disorder has long been thought to be complex, with the potential involvement of multiple genes, but methods to analyze populations…”
Get full text

Genetics for mental health clinicians: a call for a globally accessible and equitable psychiatric genetics education by Alnor, A., Besterman, A.D., Castaño, M., DeLisi, L., Grice, D.E., Lohof, F.W., Middeldorp, C., Moreno‐De‐Luca, D., Quattrone, D., Nurnberger, J.I., Nurmi, E., Ross, D.A., Soda, T., Schulze, T.G., Trost, B., Vilella, E., Yap, C., Zai, G.

Get full text

Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder by Schulze, T G, Detera-Wadleigh, S D, Akula, N, Gupta, A, Kassem, L, Steele, J, Pearl, J, Strohmaier, J, Breuer, R, Schwarz, M, Propping, P, Nöthen, M M, Cichon, S, Schumacher, J, Rietschel, M, McMahon, F J

“…Two recent reports have highlighted ANK3 as a susceptibility gene for bipolar disorder (BD). We first reported association between BD and the ANK3 marker…”
Get full text