Search Results - "Schultz, Eric M"

dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants by Williams, Lindsey N., Marjavaara, Lisette, Knowels, Gary M., Schultz, Eric M., Fox, Edward J., Chabes, Andrei, Herr, Alan J.

“…Significance An increased rate of mutation, or “mutator phenotype,” generates genetic diversity that can accelerate cancer progression or confer resistance to…”
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DNA replication error-induced extinction of diploid yeast by Herr, Alan J, Kennedy, Scott R, Knowels, Gary M, Schultz, Eric M, Preston, Bradley D

“…Genetic defects in DNA polymerase accuracy, proofreading, or mismatch repair (MMR) induce mutator phenotypes that accelerate adaptation of microbes and tumor…”
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Volatility of Mutator Phenotypes at Single Cell Resolution by Kennedy, Scott R, Schultz, Eric M, Chappell, Thomas M, Kohrn, Brendan, Knowels, Gary M, Herr, Alan J

“…Mutator phenotypes accelerate the evolutionary process of neoplastic transformation. Historically, the measurement of mutation rates has relied on scoring the…”
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dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase [epsilon] variants by Williams, Lindsey N, Marjavaara, Lisette, Knowels, Gary M, Schultz, Eric M, Fox, Edward J, Chabes, Andrei, Herr, Alan J

“…Mutator phenotypes create genetic diversity that fuels tumor evolution. DNA polymerase (Pol) ... mediates leading strand DNA replication. Proofreading defects…”
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Volatility of Mutator Phenotypes at Single Cell Resolution: e1005151 by Kennedy, Scott R, Schultz, Eric M, Chappell, Thomas M, Kohrn, Brendan, Knowels, Gary M, Herr, Alan J

“…Mutator phenotypes accelerate the evolutionary process of neoplastic transformation. Historically, the measurement of mutation rates has relied on scoring the…”
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Traumatic inferior gluteal artery pseudoaneurysm: case report and review of literature by Aydin, Ani, Lee, Christopher C., MD, Schultz, Eric, MD, Ackerman, Jeremy, MD

“…Abstract Inferior gluteal artery pseudoaneurysms are rare, with few cases reported in the recent literature. Such cases often present with a variable time…”
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