Search Results - "Schultz, Eric"

Genetic dissection of the Arabidopsis spaceflight transcriptome: Are some responses dispensable for the physiological adaptation of plants to spaceflight? by Paul, Anna-Lisa, Sng, Natasha J, Zupanska, Agata K, Krishnamurthy, Aparna, Schultz, Eric R, Ferl, Robert J

“…Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the…”
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Inaccurate Estimates of Negotiated Reimbursement Prices for Insulin by Meadows, Eric, Urgo, Ryan, Schultz, Eric H

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Forecasting hydrologic controls on juvenile anadromous fish out-migration with process-based modeling and machine learning by King, Katherine, Burgess, Michael, Schultz, Eric T., Knighton, James

“…River herring (Alosa sp.) are ecologically and economically foundational species in freshwater streams, estuaries, and oceanic ecosystems. The migration…”
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Introduction to “HaloDaSH: The Deep and Shallow History of Aquatic Life's Passages Between Marine and Freshwater Habitats” by Schultz, Eric T, Park Boush, Lisa

“…Synopsis This series of papers highlights research into how biological exchanges between salty and freshwater habitats have transformed the biosphere. Life in…”
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Genomic profiling of advanced non-small cell lung cancer in community settings: Gaps and Opportunities by Gutierrez, Martin E, Choi, Kelly, Lanman, Richard B, Licitra, Edward J, Skrzypczak, Stanley M, Pe Benito, Ruth, Wu, Tommy, Arunajadai, Srikesh, Kaur, Sukhi, Harper, Harry, Pecora, Andrew L, Schultz, Eric V, Goldberg, Stuart L

“…Abstract Background National guidelines advocate broad molecular profiling as part of the standard diagnostic evaluation for advanced non-small cell lung…”
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Polymorphisms in Human Cytomegalovirus Glycoprotein O (gO) Exert Epistatic Influences on Cell-Free and Cell-to-Cell Spread and Antibody Neutralization on gH Epitopes by Day, Le Zhang, Stegmann, Cora, Schultz, Eric P, Lanchy, Jean-Marc, Yu, Qin, Ryckman, Brent J

“…Human cytomegalovirus (HCMV) glycoproteins H and L (gH/gL) can be bound by either gO or the UL128 to UL131 proteins (referred to here as UL128-131) to form…”
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Specialization for Cell-Free or Cell-to-Cell Spread of BAC-Cloned Human Cytomegalovirus Strains Is Determined by Factors beyond the UL128-131 and RL13 Loci by Schultz, Eric P, Lanchy, Jean-Marc, Day, Le Zhang, Yu, Qin, Peterson, Christopher, Preece, Jessica, Ryckman, Brent J

“…It is widely held that clinical isolates of human cytomegalovirus (HCMV) are highly cell associated, and mutations affecting the UL128-131 and RL13 loci that…”
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Repeated Genetic Targets of Natural Selection Underlying Adaptation of Fishes to Changing Salinity by Velotta, Jonathan P, McCormick, Stephen D, Whitehead, Andrew, Durso, Catherine S, Schultz, Eric T

“…Synopsis Ecological transitions across salinity boundaries have led to some of the most important diversification events in the animal kingdom, especially…”
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Active-Site Monovalent Cations Revealed in a 1.55-Å-Resolution Hammerhead Ribozyme Structure by Anderson, Michael, Schultz, Eric P., Martick, Monika, Scott, William G.

“…We have obtained a 1.55-Å crystal structure of a hammerhead ribozyme derived from Schistosoma mansoni under conditions that permit detailed observations of Na+…”
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Neither miR-7-5p nor miR-141-3p is a major mediator of iron-responsive transferrin receptor-1 mRNA degradation by Corral, Victor M, Schultz, Eric R, Connell, Gregory J

“…The transferrin receptor (TfR1) is the principal means of iron importation for most mammalian cells, and regulation of mRNA stability is a major mechanism…”
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Organ-specific remodeling of the Arabidopsis transcriptome in response to spaceflight by Paul, Anna-Lisa, Zupanska, Agata K, Schultz, Eric R, Ferl, Robert J

“…Spaceflight presents a novel environment that is outside the evolutionary experience of terrestrial organisms. Full activation of the International Space…”
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Direct and size‐mediated effects of temperature and ration‐dependent growth rates on energy reserves in juvenile anadromous alewives (Alosa pseudoharengus) by Guo, Lian W., McCormick, Stephen D., Schultz, Eric T., Jordaan, Adrian

“…ABSTRACT Growth rate and energy reserves are important determinants of fitness and are governed by endogenous and exogenous factors. Thus, examining the…”
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Transcriptomic imprints of adaptation to fresh water: parallel evolution of osmoregulatory gene expression in the Alewife by Velotta, Jonathan P., Wegrzyn, Jill L., Ginzburg, Samuel, Kang, Lin, Czesny, Sergiusz, O'Neill, Rachel J., McCormick, Stephen D., Michalak, Pawel, Schultz, Eric T.

“…Comparative approaches in physiological genomics offer an opportunity to understand the functional importance of genes involved in niche exploitation. We used…”
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Paralog switching facilitates diadromy: ontogenetic, microevolutionary and macroevolutionary evidence by Colby, Rebecca S., McCormick, Stephen D., Velotta, Jonathan P., Jockusch, Elizabeth, Schultz, Eric T.

“…Identifying how the demands of migration are met at the level of gene expression is critical for understanding migratory physiology and can potentially reveal…”
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Seasonal reproductive allocation in landlocked Alewife Alosa pseudoharengus, in the context of niche construction and eco‐evolutionary feedbacks by Mouchlianitis, Foivos A., Schultz, Eric T., Ganias, Kostas

“…The bidirectional dynamics between species and their biotic and abiotic environments, known as eco‐evolutionary feedbacks, may shift the direction of evolution…”
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Trade-offs in osmoregulation and parallel shifts in molecular function follow ecological transitions to freshwater in the Alewife by Velotta, Jonathan P., McCormick, Stephen D., Schultz, Eric T.

“…Adaptation to freshwater may be expected to reduce performance in seawater because these environments represent opposing selective regimes. We tested for such…”
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Mutagenesis of Human Cytomegalovirus Glycoprotein L Disproportionately Disrupts gH/gL/gO over gH/gL/pUL128-131 by Schultz, Eric P, Yu, Qin, Stegmann, Cora, Day, Le Zhang, Lanchy, Jean-Marc, Ryckman, Brent J

“…Cell-free and cell-to-cell spread of herpesviruses involves a core fusion apparatus comprised of the fusion protein glycoprotein B (gB) and the regulatory…”
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Fibroblast, Epithelial and Endothelial Cell-Derived Human Cytomegalovirus Strains Display Distinct Neutralizing Antibody Responses and Varying Levels of gH/gL Complexes by Fornara, Chiara, Schultz, Eric, Lilleri, Daniele, Baldanti, Fausto, Ryckman, Brent, Gerna, Giuseppe

“…In sequential sera from pregnant women with HCMV primary infection (PI), the serum neutralizing activity is higher against virions produced in epithelial and…”
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A Patient‐Reported Outcome Instrument to Assess Symptom Burden and Predict Survival in Patients with Advanced Cancer: Flipping the Paradigm to Improve Timing of Palliative and End‐of‐Life Discussions and Reduce Unwanted Health Care Costs by Goldberg, Stuart L, Paramanathan, Dhakshila, Khoury, Raya, Patel, Sharmi, Jagun, Dayo, Arunajadai, Srikesh, DeVincenzo, Victoria, Benito, Ruth Pe, Gruman, Brooke, Kaur, Sukhi, Paddock, Scott, Norden, Andrew D, Schultz, Eric V, Hervey, John, Jordan, Terrill, Goy, Andre, Pecora, Andrew L

“…Background Discussions regarding palliative care and end‐of‐life care issues are frequently delayed past the time of usefulness, resulting in unwanted medical…”
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Prednisolone attenuates improvement of cardiac and skeletal contractile function and histopathology by lisinopril and spironolactone in the mdx mouse model of Duchenne muscular dystrophy by Janssen, Paul M L, Murray, Jason D, Schill, Kevin E, Rastogi, Neha, Schultz, Eric J, Tran, Tam, Raman, Subha V, Rafael-Fortney, Jill A

“…Duchenne muscular dystrophy (DMD) is an inherited disease that causes striated muscle weakness. Recently, we showed therapeutic effects of the combination of…”
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