Search Results - "Schuler, Sören M. M."

Preparation of Spirocyclic Vinylic Carbonates from Allylic Alcohols by Topp, Christopher, Metzler, Jan M., Dressler, Friedemann, Niedek, Dominik, Schuler, Sören M. M., Schreiner, Peter R.

“…We present the synthesis of exo- and endo-spirovinylethylene carbonates, starting from various cyclic allylic alcohols. This one-pot cascade reaction to the…”
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The Enantioselective Dakin-West Reaction by Wende, Raffael C., Seitz, Alexander, Niedek, Dominik, Schuler, Sören M. M., Hofmann, Christine, Becker, Jonathan, Schreiner, Peter R.

“…Here we report the development of the first enantioselective Dakin–West reaction, yielding α‐acetamido methylketones with up to 58 % ee with good yields. Two…”
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Total Synthesis of GE81112A: An Orthoester-Based Approach by Fayad, Scherin, Jafari, Ardalan, Schuler, Sören M. M., Kurz, Michael, Plettenburg, Oliver, Hammann, Peter E., Bauer, Armin, Jürjens, Gerrit, Pöverlein, Christoph

“…The GE81112 series, consisting of three naturally occurring tetrapeptides and synthetic derivatives, is evaluated as a potential lead structure for the…”
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Lipophilic Oligopeptides for Chemo- and Enantioselective Acyl Transfer Reactions onto Alcohols by Müller, Christian E, Zell, Daniela, Hrdina, Radim, Wende, Raffael C, Wanka, Lukas, Schuler, Sören M. M, Schreiner, Peter R

“…Inspired by the extraordinary selectivities of acylases, we envisioned the use of lipophilic oligopeptidic organocatalysts for the acylative kinetic…”
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Total Synthesis of Floyocidin B: 4,5-Regioselective Functionalization of 2-Chloropyridines by Kleiner, Yolanda, Bauer, Armin, Hammann, Peter, Schuler, Sören M. M., Pöverlein, Christoph

“…The recently discovered natural product (NP) (+)-floyocidin B with antimicrobial activity against Mycobacterium tuberculosis displays a hitherto unknown…”
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Isolation, characterization, and bioactivity profiling of oxazoline containing madurastatin siderophores from Actinomadura sp by Bill, Mona-K., Kleiner, Yolanda, Flügel, Jana L., Kurz, Michael, Spohn, Marius, Marner, Michael, Mihajlovic, Sanja, Vilcinskas, Andreas, Schäberle, Till F., Hammann, Peter E., Patras, Maria A., Schuler, Sören M. M.

“…Nine new hydroxyphenyloxazolines, madurastatin B4, C2, D3 and D4, E1 and E2, F1 as well as G1 and G2 ( 8 – 16 ), along with two new enantiomers of madurastatin…”
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Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners by Frank, Nicolas A, Széles, Márió, Akone, Sergi H, Rasheed, Sari, Hüttel, Stephan, Frewert, Simon, Hamed, Mostafa M, Herrmann, Jennifer, Schuler, Sören M M, Hirsch, Anna K H, Müller, Rolf

“…Myxobacteria represent a viable source of chemically diverse and biologically active secondary metabolites. The myxochelins are a well-studied family of…”
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Full Profiling of GE81112A, an Underexplored Tetrapeptide Antibiotic with Activity against Gram-Negative Pathogens by Schuler, Sören M M, Jürjens, Gerrit, Marker, Alexander, Hemmann, Ulrike, Rey, Astrid, Yvon, Stéphane, Lagrevol, Marjorie, Hamiti, Mohamed, Nguyen, Fabian, Hirsch, Rolf, Pöverlein, Christoph, Vilcinskas, Andreas, Hammann, Peter, Wilson, Daniel N, Mourez, Michael, Coyne, Sebastien, Bauer, Armin

“…After the first total synthesis combined with structure revision, we performed thorough and profiling of the underexplored tetrapeptide GE81112A. From the…”
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Total Synthesis and Structure Revision of (-)-Avicennone C by Kleiner, Yolanda, Hammann, Peter, Becker, Jonathan, Bauer, Armin, Pöverlein, Christoph, Schuler, Sören M M

“…All four possible stereoisomers of the natural product (-)-avicennone C were synthesized using two different methods for ring closure. The absolute…”
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Novel Glycerophospholipid, Lipo- and N -acyl Amino Acids from Bacteroidetes: Isolation, Structure Elucidation and Bioactivity by Bill, Mona-Katharina, Brinkmann, Stephan, Oberpaul, Markus, Patras, Maria A, Leis, Benedikt, Marner, Michael, Maitre, Marc-Philippe, Hammann, Peter E, Vilcinskas, Andreas, Schuler, Sören M M, Schäberle, Till F

“…The 'core' metabolome of the Bacteroidetes genus was recently discovered to consist of only seven metabolites. A structural relationship in terms of shared…”
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The Enantioselective Dakin-West Reaction by Wende, Raffael C., Seitz, Alexander, Niedek, Dominik, Schuler, Sören M. M., Hofmann, Christine, Becker, Jonathan, Schreiner, Peter R.

“…Here we report the development of the first enantioselective Dakin–West reaction, yielding α‐acetamido methylketones with up to 58 % ee with good yields. Two…”
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Total Synthesis and Structural Revision of the Antibiotic Tetrapeptide GE81112A by Jürjens, Gerrit, Schuler, Sören M. M., Kurz, Michael, Petit, Sylvain, Couturier, Cédric, Jeannot, Frédéric, Nguyen, Fabian, Wende, Raffael C., Hammann, Peter E., Wilson, Daniel N., Bacqué, Eric, Pöverlein, Christoph, Bauer, Armin

“…The total synthesis of the naturally occurring antibiotic GE81112A, a densely functionalized tetrapeptide, is reported. Comparison of spectral data with those…”
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The Discovery and Structure‐Activity Evaluation of (+)‐Floyocidin B and Synthetic Analogs by Kleiner, Yolanda, Pöverlein, Christoph, Klädtke, Jannike, Kurz, Michael, König, Henrik F., Becker, Jonathan, Mihajlovic, Sanja, Zubeil, Florian, Marner, Michael, Vilcinskas, Andreas, Schäberle, Till F., Hammann, Peter, Schuler, Sören M. M., Bauer, Armin

“…Tuberculosis represents one of the ten most common courses of death worldwide and the emergence of multidrug‐resistant M. tuberculosis makes the discovery of…”
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En route to multicatalysis: kinetic resolution of trans-cycloalkane-1,2-diols via oxidative esterification by Hofmann, Christine, Schuler, Sören M M, Wende, Raffael C, Schreiner, Peter R

“…We demonstrate the application of a multicatalyst to the oxidation of a broad variety of aldehydes and subsequent enantioselective esterification of the…”
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Functionality, Effectiveness, and Mechanistic Evaluation of a Multicatalyst-Promoted Reaction Sequence by Electrospray Ionization Mass Spectrometry by Alachraf, M. Wasim, Wende, Raffael C., Schuler, Sören M. M., Schreiner, Peter R., Schrader, Wolfgang

“…A multicatalytic three‐step reaction consisting of epoxidation, hydrolysis, and enantioselective monoacylation of cyclohexene was studied by using mass…”
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Totalsynthese und Strukturkorrektur des antibiotisch wirksamen Tetrapeptids GE81112A by Jürjens, Gerrit, Schuler, Sören M. M., Kurz, Michael, Petit, Sylvain, Couturier, Cédric, Jeannot, Frédéric, Nguyen, Fabian, Wende, Raffael C., Hammann, Peter E., Wilson, Daniel N., Bacqué, Eric, Pöverlein, Christoph, Bauer, Armin

“…Die erste Totalsynthese des antibiotisch wirksamen Naturstoffs GE81112A, eines hoch funktionalisierten Tetrapeptids, wurde abgeschlossen. Der Vergleich der…”
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