Search Results - "Schug, J."
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Transcriptomes of the major human pancreatic cell types
Published in Diabetologia (01-11-2011)“…Aims/hypothesis We sought to determine the mRNA transcriptome of all major human pancreatic endocrine and exocrine cell subtypes, including human alpha, beta,…”
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Decreased Platelet Reactivity and Function in a Mouse Model of Human Pancreatic Cancer
Published in Thrombosis and haemostasis (01-05-2023)“…Cancer patients have increased thrombosis and bleeding compared with the general population. Cancer is associated with activation of both platelets and…”
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Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity
Published in The Journal of neuroscience (26-08-2015)“…Bexarotene-activated retinoid X receptors (RXRs) ameliorate memory deficits in Alzheimer's disease mouse models, including mice expressing human apolipoprotein…”
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Disease-associated loci are significantly over-represented among genes bound by transcription factor 7-like 2 (TCF7L2) in vivo
Published in Diabetologia (01-11-2010)“…Aims/hypothesis Transcription factor 7-like 2 (TCF7L2) has been strongly implicated in type 2 diabetes and cancer. Our goal was to identify the DNA sequences…”
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Pharmacology of pannexin channels
Published in Current opinion in pharmacology (01-04-2023)“…Pannexin channels play fundamental roles in regulating inflammation and have been implicated in many diseases including hypertension, stroke, and neuropathic…”
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Amaranthus hypochondriacus seeds as a rich source of cysteine rich bioactive peptides
Published in Food chemistry (30-05-2022)“…[Display omitted] •5 cysteine-rich peptide (CRPs) families found in A. hypochondriacus seeds.•Post-translational modifications identified on mature CRPs may…”
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Erratum to: Transcriptomes of the major human pancreatic cell types
Published in Diabetologia (01-05-2013)Get full text
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Both G protein–coupled and immunoreceptor tyrosine-based activation motif receptors mediate venous thrombosis in mice
Published in Blood (26-05-2022)“…Platelets are critical in hemostasis and a major contributor to arterial thrombosis (AT). (Pre)clinical studies suggest platelets also contribute to venous…”
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Leveraging orthogonal mass spectrometry based strategies for comprehensive sequencing and characterization of ribosomal antimicrobial peptide natural products
Published in Natural product reports (01-03-2021)“…Covering: Up to July 2020Ribosomal antimicrobial peptide (AMP) natural products, also known as ribosomally synthesized and post-translationally modified…”
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Penetration depth scaling for impact into wet granular packings
Published in Physical review. E, Statistical, nonlinear, and soft matter physics (09-02-2015)“…We present experimental measurements of penetration depths for the impact of spheres into wetted granular media. We observe that the penetration depth in the…”
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Loss of P2Y1 receptor desensitization does not impact hemostasis or thrombosis despite increased platelet reactivity in vitro
Published in Journal of thrombosis and haemostasis (01-07-2023)“…The hemostatic plug formation at sites of vascular injury is strongly dependent on rapid platelet activation and integrin-mediated adhesion and aggregation…”
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PlasmoDB: An integrative database of the Plasmodium falciparum genome. Tools for accessing and analyzing finished and unfinished sequence data
Published in Nucleic acids research (01-01-2001)“…The Plasmodium falciparum Genome Database (http://PlasmoDB.org ) integrates sequence information, automated analyses and annotation data emerging from the…”
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A relational schema for both array-based and SAGE gene expression experiments
Published in Bioinformatics (01-04-2001)“…Motivation and Results: A relational schema is described for capturing highly parallel gene expression experiments using different technologies. This schema…”
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EVALUATING PHENOTYPIC DIFFERENCES IN IDIOPATHIC AND DIABETIC FROZEN SHOULDR THROUGH GENOME WIDE RNA ANALYSIS
Published in Osteoarthritis and cartilage (01-04-2022)Get full text
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Modeling and analyzing biomolecular networks
Published in Computing in science & engineering (01-01-2002)“…The authors argue for the need to model and analyze biological networks at molecular and cellular levels. They propose a computational toolbox for biologists…”
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Emotional expressivity as a signal of cooperation
Published in Evolution and human behavior (01-03-2010)“…Abstract Previous research has suggested that the spontaneous display of positive emotion may be a reliable signal of cooperative tendency in humans…”
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Glucocorticoid receptor-dependent gene regulatory networks
Published in PLoS genetics (01-08-2005)“…While the molecular mechanisms of glucocorticoid regulation of transcription have been studied in detail, the global networks regulated by the glucocorticoid…”
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PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data
Published in Nucleic acids research (01-01-2003)“…PlasmoDB (http://PlasmoDB.org) is the official database of the Plasmodium falciparum genome sequencing consortium. This resource incorporates the recently…”
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MULTI-OMICS PROFILING IDENTIFIES APOE-ALLELE-ASSOCIATED LIPID AND GENE EXPRESSION PATTERNS IN ALZHEIMER'S DISEASE
Published in Alzheimer's & dementia (01-07-2018)Get full text
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Ground-state multiplicities of atoms and positive ions
Published in Theoretical chemistry accounts (21-03-2000)Get full text
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