Search Results - "Schuch, Gunter"

Fluorouracil, Leucovorin, and Oxaliplatin With and Without Cetuximab in the First-Line Treatment of Metastatic Colorectal Cancer by BOKEMEYER, Carsten, BONDARENKO, Igor, LOOS, Anja H, ZUBEL, Angela, KORALEWSKI, Piotr, MAKHSON, Anatoly, HARTMANN, Joerg T, APARICIO, Jorge, DE BRAUD, Filippo, DONEA, Serban, LUDWIG, Heinz, SCHUCH, Gunter, STROH, Christopher

“…This randomized study assessed whether the best overall response rate (ORR) of cetuximab combined with oxaliplatin, leucovorin, and fluorouracil (FOLFOX-4) was…”
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Phase III Trial in Metastatic Gastroesophageal Adenocarcinoma with Fluorouracil, Leucovorin Plus Either Oxaliplatin or Cisplatin: A Study of the Arbeitsgemeinschaft Internistische Onkologie by AL-BATRAN, Salah-Eddin, HARTMANN, Joerg Thomas, SCHUCH, Gunter, STOEHLMACHER, Jan, DERIGS, Hans Günter, HEGEWISCH-BECKER, Susanna, GROSSMANN, Johannes, PAULIGK, Claudia, ATMACA, Akin, BOKEMEYER, Carsten, KNUTH, Alexander, JÄGER, Elke, PROBST, Stephan, SCHMALENBERG, Harald, HOLLERBACH, Stephan, HOFHEINZ, Ralf, RETHWISCH, Volker, SEIPELT, Gernot, HOMANN, Nils, WILHELM, Gerhard

“…This study was designed to compare fluorouracil, leucovorin, and oxaliplatin with fluorouracil, leucovorin, and cisplatin in patients with advanced gastric…”
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Sequential Versus Combination Therapy of Metastatic Colorectal Cancer Using Fluoropyrimidines, Irinotecan, and Bevacizumab: A Randomized, Controlled Study-XELAVIRI (AIO KRK0110) by Modest, Dominik Paul, Fischer von Weikersthal, Ludwig, Decker, Thomas, Vehling-Kaiser, Ursula, Uhlig, Jens, Schenk, Michael, Freiberg-Richter, Jens, Peuser, Bettina, Denzlinger, Claudio, Peveling Genannt Reddemann, Christina, Graeven, Ullrich, Schuch, Gunter, Schwaner, Ingo, Stahler, Arndt, Jung, Andreas, Kirchner, Thomas, Held, Swantje, Stintzing, Sebastian, Giessen-Jung, Clemens, Heinemann, Volker

“…The XELAVIRI trial investigated the optimal treatment strategy for patients with untreated metastatic colorectal cancer. We tested the noninferiority of…”
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Pharmacogenetic Analyses of a Phase III Trial in Metastatic Gastroesophageal Adenocarcinoma With Fluorouracil and Leucovorin Plus Either Oxaliplatin or Cisplatin: A Study of the Arbeitsgemeinschaft Internistische Onkologie by GOEKKURT, Eray, AL-BATRAN, Salah-Eddin, HARTMANN, Jörg T, MOGCK, Ulrike, SCHUCH, Gunter, KRAMER, Michael, JAEGER, Elke, BOKEMEYER, Carsten, EHNINGER, Gerhard, STOEHLMACHER, Jan

“…To evaluate the association of germ-line polymorphisms of genes that may impact treatment outcome of platinum and fluorouracil combination chemotherapy in…”
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Targeting CD38-Expressing Multiple Myeloma and Burkitt Lymphoma Cells In Vitro with Nanobody-Based Chimeric Antigen Receptors (Nb-CARs) by Hambach, Julia, Riecken, Kristoffer, Cichutek, Sophia, Schütze, Kerstin, Albrecht, Birte, Petry, Katharina, Röckendorf, Jana Larissa, Baum, Natalie, Kröger, Nicolaus, Hansen, Timon, Schuch, Gunter, Haag, Friedrich, Adam, Gerhard, Fehse, Boris, Bannas, Peter, Koch-Nolte, Friedrich

“…The NAD-hydrolyzing ecto-enzyme CD38 is overexpressed by multiple myeloma and other hematological malignancies. We recently generated CD38-specific nanobodies,…”
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Cilengitide induces cellular detachment and apoptosis in endothelial and glioma cells mediated by inhibition of FAK/src/AKT pathway by Oliveira-Ferrer, Leticia, Hauschild, Jessica, Fiedler, Walter, Bokemeyer, Carsten, Nippgen, Johannes, Celik, Ilhan, Schuch, Gunter

“…The antiangiogenic agent cilengitide disrupts integrin binding to the extracellular matrix leading to apoptosis of activated endothelial cells. Integrins are…”
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In vitro differentiation of endothelial cells from AC133-positive progenitor cells by GEHLING, U. M, ERGÜN, S, KLUGE, K, SCHÄFER, B, HOSSFELD, D. K, FIEDLER, W, SCHUMACHER, U, WAGENER, C, PANTEL, K, OTTE, M, SCHUCH, G, SCHAFHAUSEN, P, MENDE, T, KILIC, N

“…Recent findings support the hypothesis that the CD34(+)-cell population in bone marrow and peripheral blood contains hematopoietic and endothelial progenitor…”
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Generation of histocompatible tissues using nuclear transplantation by Atala, Anthony, Lanza, Robert P, Chung, Ho Yun, Yoo, James J, Wettstein, Peter J, Blackwell, Catherine, Borson, Nancy, Hofmeister, Erik, Schuch, Gunter, Soker, Shay, Moraes, Carlos T, West, Michael D

“…Nuclear transplantation (therapeutic cloning) could theoretically provide a limitless source of cells for regenerative therapy. Although the cloned cells would…”
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Butene isomers separation on titania supported MFI membranes at conditions relevant for practice by Voß, Hartwig, Diefenbacher, Armin, Schuch, Gunter, Richter, Hannes, Voigt, Ingolf, Noack, Manfred, Caro, Jürgen

“…MFI membranes (ZSM-5 and silicalite-1) prepared by secondary growth on the core side of tubular titania supports, have been evaluated in the C 4 olefin isomers…”
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Analysis of Concerted Expression of Angiogenic Growth Factors in Acute Myeloid Leukemia: Expression of Angiopoietin-2 Represents an Independent Prognostic Factor for Overall Survival by LOGES, Sonja, HEIL, Gerhard, BRUWELEIT, Melanie, SCHODER, Volker, BUTZAL, Martin, FISCHER, Uta, GEHLING, Ursula M, SCHUCH, Gunter, HOSSFELD, Dieter K, FIEDLER, Walter

“…Bone marrow neoangiogenesis plays an important pathogenetic and possible prognostic role in acute myeloid leukemia (AML). Members of the vascular endothelial…”
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In vivo administration of vascular endothelial growth factor (VEGF) and its antagonist, soluble neuropilin-1, predicts a role of VEGF in the progression of acute myeloid leukemia in vivo by Schuch, Gunter, Machluf, Marcelle, Bartsch, Georg, Nomi, Masashi, Richard, Henri, Atala, Anthony, Soker, Shay

“…Recent findings implied that the progression of hematologic malignancies, like that of solid tumors, is dependent on neovascularization. Recent studies on…”
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Propagation, expansion, and multilineage differentiation of human somatic stem cells from dermal progenitors by Bartsch, Georg, Yoo, James J, De Coppi, Paolo, Siddiqui, M Minhaj, Schuch, Gunter, Pohl, Hans G, Fuhr, Jasmin, Perin, Laura, Soker, Shay, Atala, Anthony

“…We isolated multipotential mesenchymal stem cells (MSC) from human postnatal dermal tissues. The isolated cells were expanded and maintained for over 100…”
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Cilengitide inhibits proliferation and differentiation of human endothelial progenitor cells in vitro by Loges, Sonja, Butzal, Martin, Otten, Jasmin, Schweizer, Michaela, Fischer, Uta, Bokemeyer, Carsten, Hossfeld, Dieter K., Schuch, Gunter, Fiedler, Walter

“…Bone marrow derived hematopoietic stem cells can function as endothelial progenitor cells. They are recruited to malignant tumors and differentiate into…”
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Determination of Microvessel Density by Quantitative Real-time PCR in Esophageal Cancer: Correlation with Histologic Methods, Angiogenic Growth Factor Expression, and Lymph Node Metastasis by LOGES, Sonja, CLAUSEN, Henning, BOKEMEYER, Carsten, FIEDLER, Walter, REICHELT, Uta, BUBENHEIM, Michael, ERBERSDOBLER, Andreas, SCHURR, Paulus, YEKEBAS, Emre, SCHUCH, Gunter, IZBICKI, Jakob, PANTEL, Klaus

“…Purpose: Angiogenesis and lymphangiogenesis are important steps in tumor growth and dissemination and are of prognostic importance in solid tumors. The…”
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Expression of CEACAM-1 in Pulmonary Adenocarcinomas and their Metastases by THÖM, Ina, SCHULT-KRONEFELD, Olaf, LAACK, Eckart, BURKHOLDER, Iris, SCHUCH, Gunter, ANDRITZKY, Birte, KASTENDIECK, Hartwig, EDLER, Lutz, WAGENER, Christoph, BOKEMEYER, Carsten, SCHUMACHER, Udo

“…Background: CEACAM-1 is involved in intercellular adhesion and is expressed in a variety of human tissues. In cases of malignant transformation, a…”
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Significance of vascular stabilization for tumor growth and metastasis by Ergun, Suleyman, Tilki, Derya, Oliveira-Ferrer, Leticia, Schuch, Gunter, Kilic, Nerbil

“…This mini review highlights the role of vascular stabilization which is apparently mediated by factors belonging to both the pro- and anti-angiogenic group…”
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Identification of the adult human hemangioblast by Loges, Sonja, Fehse, Boris, Brockmann, Marc A, Lamszus, Katrin, Butzal, Martin, Guckenbiehl, Markus, Schuch, Gunter, Ergün, Süleyman, Fischer, Uta, Zander, Axel R, Hossfeld, Dieter K, Fiedler, Walter, Gehling, Ursula M

“…Recent studies show that human CD133(+) (previously known as AC133(+)) cells from mobilized peripheral blood consist of stem cells with either hematopoietic or…”
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Evolving role of cetuximab in the treatment of colorectal cancer by Schuch, Gunter

“…Gunter Schuch, Sebastian Kobold, Carsten BokemeyerDepartment of Oncology, Hematology, and Bone Marrow Transplantation with Section of Pneumology, University…”
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Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial by Al-Batran, Salah-Eddin, Homann, Nils, Pauligk, Claudia, Goetze, Thorsten O, Meiler, Johannes, Kasper, Stefan, Kopp, Hans-Georg, Mayer, Frank, Haag, Georg Martin, Luley, Kim, Lindig, Udo, Schmiegel, Wolff, Pohl, Michael, Stoehlmacher, Jan, Folprecht, Gunnar, Probst, Stephan, Prasnikar, Nicole, Fischbach, Wolfgang, Mahlberg, Rolf, Trojan, Jörg, Koenigsmann, Michael, Martens, Uwe M, Thuss-Patience, Peter, Egger, Matthias, Block, Andreas, Heinemann, Volker, Illerhaus, Gerald, Moehler, Markus, Schenk, Michael, Kullmann, Frank, Behringer, Dirk M, Heike, Michael, Pink, Daniel, Teschendorf, Christian, Löhr, Carmen, Bernhard, Helga, Schuch, Gunter, Rethwisch, Volker, von Weikersthal, Ludwig Fischer, Hartmann, Jörg T, Kneba, Michael, Daum, Severin, Schulmann, Karsten, Weniger, Jörg, Belle, Sebastian, Gaiser, Timo, Oduncu, Fuat S, Güntner, Martina, Hozaeel, Wael, Reichart, Alexander, Jäger, Elke, Kraus, Thomas, Mönig, Stefan, Bechstein, Wolf O, Schuler, Martin, Schmalenberg, Harald, Hofheinz, Ralf D

“…Docetaxel-based chemotherapy is effective in metastatic gastric and gastro-oesophageal junction adenocarcinoma. This study reports on the safety and efficacy…”
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Association of SARS-CoV-2 vaccinations and personal protective measures with seroconversion and risk of infection in a large real-world cohort of patients with cancer by Michaeli, Thomas, Thilo, Niklas, Michaeli, Daniel Tobias, Beth, Helge, Hoffmann, Friederike, Janning, Melanie, Engel, Erik, Schuch, Gunter, Loges, Sonja

“…e18835 Background: Longitudinal data assessing seroconversion after different doses of SARS-CoV-2 vaccines and the role of personal protective measures to…”
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