Search Results - "Schubert, Rajib"
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Nanomechanical mapping of first binding steps of a virus to animal cells
Published in Nature nanotechnology (01-02-2017)“…Viral infection is initiated when a virus binds to cell surface receptors. Because the cell membrane is dynamic and heterogeneous, imaging living cells and…”
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2
Kin discrimination in social yeast is mediated by cell surface receptors of the Flo11 adhesin family
Published in eLife (14-04-2020)“…Microorganisms have evolved specific cell surface molecules that enable discrimination between cells from the same and from a different kind. Here, we…”
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3
The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody
Published in Proceedings of the National Academy of Sciences - PNAS (25-05-2021)“…The goal of cancer-drug delivery is to achieve high levels of therapeutics within tumors with minimal systemic exposure that could cause toxicity. Producing…”
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Transcriptional Dysregulation and Impaired Neuronal Activity in FMR1 Knock-Out and Fragile X Patients’ iPSC-Derived Models
Published in International journal of molecular sciences (01-10-2023)“…Fragile X syndrome (FXS) is caused by a repression of the FMR1 gene that codes the Fragile X mental retardation protein (FMRP), an RNA binding protein involved…”
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5
The biomechanical properties of an epithelial tissue determine the location of its vasculature
Published in Nature communications (20-12-2016)“…An important question is how growing tissues establish a blood vessel network. Here we study vascular network formation in pancreatic islets, endocrine tissues…”
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6
Assay for characterizing the recovery of vertebrate cells for adhesion measurements by single-cell force spectroscopy
Published in FEBS letters (01-10-2014)“…•Cell recovery after detachment from tissue-culture flasks is prerequisite for SCFS.•We introduce an SCFS assay to quantitatively characterize this cell…”
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7
CRISPR-clear imaging of melanin-rich B16-derived solid tumors
Published in Communications biology (04-04-2023)“…Tissue clearing combined with deep imaging has emerged as a powerful technology to expand classical histological techniques. Current techniques have been…”
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8
Targeting Single Cell Networks for Gene Expression using Mechanical Stamping
Published in Biophysical journal (28-01-2014)Get full text
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A practical guide to quantify cell adhesion using single-cell force spectroscopy
Published in Methods (San Diego, Calif.) (01-04-2013)“…[Display omitted] ► A practical guide to single-cell force spectroscopy. ► Quantifying the adhesion of living animal cells to various substrates. ►…”
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Magnetically guided virus stamping for the targeted infection of single cells or groups of cells
Published in Nature protocols (01-11-2019)“…To understand and control complex tissues, the ability to genetically manipulate single cells is required. However, current delivery methods for the genetic…”
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Deciphering Teneurin Domains That Facilitate Cellular Recognition, Cell–Cell Adhesion, and Neurite Outgrowth Using Atomic Force Microscopy-Based Single-Cell Force Spectroscopy
Published in Nano letters (12-06-2013)“…Teneurins are evolutionarily conserved transmembrane receptors that function as axon guidance and target selection molecules in the developing nervous system…”
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Transcriptional Dysregulation and Impaired Neuronal Activity in IFMR1/I Knock-Out and Fragile X Patients’ iPSC-Derived Models
Published in International journal of molecular sciences (01-10-2023)“…Fragile X syndrome (FXS) is caused by a repression of the FMR1 gene that codes the Fragile X mental retardation protein (FMRP), an RNA binding protein involved…”
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13
Virus stamping for targeted single-cell infection in vitro and in vivo
Published in Nature biotechnology (01-01-2018)“…Viruses are transduced to single cells in tissues, organoids and in the mouse brain using mechanical carriers. Genetic engineering by viral infection of single…”
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14
Strongly Binding Cell-Adhesive Polypeptides of Programmable Valencies
Published in Angewandte Chemie (International ed.) (08-03-2010)“…Longer and stronger: Engineered multivalent polypeptides were used to increase and tune the adhesion strength of cells to surfaces. Monodisperse polypeptides…”
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Strongly Binding Cell-Adhesive Polypeptides of Programmable Valencies
Published in Angewandte Chemie (08-03-2010)“…Länger und stärker: Mit maßgeschneiderten multivalenten Polypeptiden – monodispersen Polypeptiden mit einer Zelladhäsionssequenz mit programmierbarer Valenz –…”
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Strongly Binding Cell‐Adhesive Polypeptides of Programmable Valencies
Published in Angewandte Chemie (08-03-2010)Get full text
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17
Multivalent polypeptides for tunable cell adhesion
Published in Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference (NEBEC) (01-03-2010)“…Cell adhesion to surfaces has applications in biomaterials science, surface chemistry, and micropatterning technologies. Control of this process is currently…”
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