Search Results - "Schütz, Günther"

Disrupting Hypothalamic Glucocorticoid Receptors Causes HPA Axis Hyperactivity and Excess Adiposity by Laryea, Gloria, Schütz, Günther, Muglia, Louis J

“…The glucocorticoid receptor (GR) regulates hypothalamic-pituitary-adrenal (HPA) axis activity during the stress response. The paraventricular nucleus (PVN) is…”
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Metaplasticity of amygdalar responses to the stress hormone corticosterone by Karst, Henk, Berger, Stefan, Erdmann, Gitta, Schütz, Günther, Joëls, Mrian, Pfaff, Donald W.

“…High levels of corticosteroids (as circulate after stress) quickly and reversibly enhance hippocampal glutamatergic transmission via nongenomic actions…”
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Somatic Sex Reprogramming of Adult Ovaries to Testes by FOXL2 Ablation by Uhlenhaut, N. Henriette, Jakob, Susanne, Anlag, Katrin, Eisenberger, Tobias, Sekido, Ryohei, Kress, Jana, Treier, Anna-Corina, Klugmann, Claudia, Klasen, Christian, Holter, Nadine I., Riethmacher, Dieter, Schütz, Günther, Cooney, Austin J., Lovell-Badge, Robin, Treier, Mathias

“…In mammals, the transcription factor SRY, encoded by the Y chromosome, is normally responsible for triggering the indifferent gonads to develop as testes…”
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Deletion of Cardiomyocyte Mineralocorticoid Receptor Ameliorates Adverse Remodeling After Myocardial Infarction by FRACCAROLLO, Daniela, BERGER, Stefan, GALUPPO, Paolo, KNEITZ, Susanne, HEIN, Lutz, SCHÜTZ, Günther, FRANTZ, Stefan, ERTL, Georg, BAUERSACHS, Johann

“…Mineralocorticoid receptor (MR) blockade improves morbidity and mortality among patients with heart failure; however, the underlying mechanisms are still under…”
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Inducible gene inactivation in neurons of the adult mouse forebrain by Erdmann, Gitta, Schütz, Günther, Berger, Stefan

“…The analysis of the role of genes in important brain functions like learning, memory and synaptic plasticity requires gene inactivation at the adult stage to…”
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Resetting of Circadian Time in Peripheral Tissues by Glucocorticoid Signaling by Balsalobre, Aurélio, Brown, Steven A., Marcacci, Lysiane, Tronche, FranÇois, Kellendonk, Christoph, Reichardt, Holger M., Schütz, Günther, Schibler, Ueli

“…In mammals, circadian oscillators reside not only in the suprachiasmatic nucleus of the brain, which harbors the central pacemaker, but also in most peripheral…”
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Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum by Yadav, Vijay K., Ryu, Je-Hwang, Suda, Nina, Tanaka, Kenji F., Gingrich, Jay A., Schütz, Günther, Glorieux, Francis H., Chiang, Cherie Y., Zajac, Jeffrey D., Insogna, Karl L., Mann, J. John, Hen, Rene, Ducy, Patricia, Karsenty, Gerard

“…Loss- and gain-of-function mutations in the broadly expressed gene Lrp5 affect bone formation, causing osteoporosis and high bone mass, respectively. Although…”
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MicroRNA loss enhances learning and memory in mice by Konopka, Witold, Kiryk, Anna, Novak, Martin, Herwerth, Marina, Parkitna, Jan Rodriguez, Wawrzyniak, Marcin, Kowarsch, Andreas, Michaluk, Piotr, Dzwonek, Joanna, Arnsperger, Tabea, Wilczynski, Grzegorz, Merkenschlager, Matthias, Theis, Fabian J, Köhr, Georg, Kaczmarek, Leszek, Schütz, Günther

“…Dicer-dependent noncoding RNAs, including microRNAs (miRNAs), play an important role in a modulation of translation of mRNA transcripts necessary for…”
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Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1 by Refojo, Damian, Schweizer, Martin, Kuehne, Claudia, Ehrenberg, Stefanie, Thoeringer, Christoph, Vogl, Annette M., Dedic, Nina, Schumacher, Marion, von Wolff, Gregor, Avrabos, Charilaos, Touma, Chadi, Engblom, David, Schütz, Günther, Nave, Klaus-Armin, Eder, Matthias, Wotjak, Carsten T., Sillaber, Inge, Holsboer, Florian, Wurst, Wolfgang, Deussing, Jan M.

“…The corticotropin-releasing hormone receptor 1 (CRHR1) critically controls behavioral adaptation to stress and is causally linked to emotional disorders. Using…”
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Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice by Fritz, Michael, Klawonn, Anna M, Nilsson, Anna, Singh, Anand Kumar, Zajdel, Joanna, Wilhelms, Daniel Björk, Lazarus, Michael, Löfberg, Andreas, Jaarola, Maarit, Kugelberg, Unn Örtegren, Billiar, Timothy R, Hackam, David J, Sodhi, Chhinder P, Breyer, Matthew D, Jakobsson, Johan, Schwaninger, Markus, Schütz, Günther, Parkitna, Jan Rodriguez, Saper, Clifford B, Blomqvist, Anders, Engblom, David

“…Systemic inflammation causes malaise and general feelings of discomfort. This fundamental aspect of the sickness response reduces the quality of life for…”
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role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction by Fusco, Salvatore, Ripoli, Cristian, Podda, Maria Vittoria, Ranieri, Sofia Chiatamone, Leone, Lucia, Toietta, Gabriele, McBurney, Michael W, Schütz, Günther, Riccio, Antonella, Grassi, Claudio, Galeotti, Tommaso, Pani, Giovambattista

“…Calorie restriction delays brain senescence and prevents neurodegeneration, but critical regulators of these beneficial responses other than the NAD+-dependent…”
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CB1 Cannabinoid Receptors and On-Demand Defense against Excitotoxicity by Marsicano, Giovanni, Goodenough, Sharon, Monory, Krisztina, Hermann, Heike, Eder, Matthias, Cannich, Astrid, Azad, Shahnaz C., Cascio, Maria Grazia, Gutiérrez, Silvia Ortega, van der Stelt, Mario, López-Rodríguez, Maria Luz, Casanova, Emilio, Schütz, Günther, Zieglgänsberger, Walter, Di Marzo, Vincenzo, Behl, Christian, Lutz, Beat

“…Abnormally high spiking activity can damage neurons. Signaling systems to protect neurons from the consequences of abnormal discharge activity have been…”
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Mineralocorticoid Receptors Are Indispensable for Nongenomic Modulation of Hippocampal Glutamate Transmission by Corticosterone by Henk Karst, Berger, Stefan, Marc Turiault, Tronche, Francois, Schütz, Günther, Joëls, Marian

“…The adrenal hormone corticosterone transcriptionally regulates responsive genes in the rodent hippocampus through nuclear mineralocorticoid and glucocorticoid…”
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Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice by Monory, Krisztina, Blaudzun, Heike, Massa, Federico, Kaiser, Nadine, Lemberger, Thomas, Schütz, Günther, Wotjak, Carsten T, Lutz, Beat, Marsicano, Giovanni

“…Marijuana and its main psychotropic ingredient Delta(9)-tetrahydrocannabinol (THC) exert a plethora of psychoactive effects through the activation of the…”
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Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling by Rieker, Claus, Engblom, David, Kreiner, Grzegorz, Domanskyi, Andrii, Schober, Andreas, Stotz, Stefanie, Neumann, Manuela, Yuan, Xuejun, Grummt, Ingrid, Schütz, Günther, Parlato, Rosanna

“…The nucleolus represents an essential stress sensor for the cell. However, the molecular consequences of nucleolar damage and their possible link with…”
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Definition of Estrogen Receptor Pathway Critical for Estrogen Positive Feedback to Gonadotropin-Releasing Hormone Neurons and Fertility by Wintermantel, Tim M., Campbell, Rebecca E., Porteous, Robert, Bock, Dagmar, Gröne, Hermann-Josef, Todman, Martin G., Korach, Kenneth S., Greiner, Erich, Pérez, Cristian A., Schütz, Günther, Herbison, Allan E.

“…The mechanisms through which estrogen regulates gonadotropin-releasing hormone (GnRH) neurons to control mammalian ovulation are unknown. We found that…”
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The nuclear receptor tailless is required for neurogenesis in the adult subventricular zone by Liu, Hai-Kun, Belz, Thorsten, Bock, Dagmar, Takacs, Andrea, Wu, Hui, Lichter, Peter, Chai, Minqiang, Schütz, Günther

“…The tailless (Tlx) gene encodes an orphan nuclear receptor that is expressed by neural stem/progenitor cells in the adult brain of the subventricular zone…”
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The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation by Liu, Hai-Kun, Wang, Ying, Belz, Thorsten, Bock, Dagmar, Takacs, Andrea, Radlwimmer, Bernhard, Barbus, Sebastian, Reifenberger, Guido, Lichter, Peter, Schütz, Günther

“…Malignant gliomas are the most common primary brain tumors, and are associated with frequent resistance to therapy as well as poor prognosis. Here we…”
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Myeloid-Specific Deletion of the Mineralocorticoid Receptor Reduces Infarct Volume and Alters Inflammation During Cerebral Ischemia by FRIELER, Ryan A, HE MENG, SHENG ZHONG DUAN, BERGER, Stefan, SCHÜTZ, Günther, YANGDONG HE, GUOHUA XI, WANG, Michael M, MORTENSEN, Richard M

“…mineralocorticoid receptor (MR) antagonists have protective effects in rodent models of ischemic stroke, but the cell type-specific actions of these drugs are…”
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Glutamate Receptors on Dopamine Neurons Control the Persistence of Cocaine Seeking by Engblom, David, Bilbao, Ainhoa, Sanchis-Segura, Carles, Dahan, Lionel, Perreau-Lenz, Stéphanie, Balland, Bénédicte, Parkitna, Jan Rodriguez, Luján, Rafael, Halbout, Briac, Mameli, Manuel, Parlato, Rosanna, Sprengel, Rolf, Lüscher, Christian, Schütz, Günther, Spanagel, Rainer

“…Cocaine strengthens excitatory synapses onto midbrain dopamine neurons through the synaptic delivery of GluR1-containing AMPA receptors. This cocaine-evoked…”
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