Search Results - "Schu, P"

Hsc70 phosphorylation patterns and calmodulin regulate AP2 Clathrin-Coated-Vesicle life span for cell adhesion protein transport by Sengül, G.F., Mishra, R., Candiello, E., Schu, P.

“…AP2 forms AP2 CCV with clathrin and over 60 additional coat proteins. Due to this complexity, we have a limited understanding of CCV life cycle regulation…”
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Synaptic AP2 CCV life cycle regulation by the Eps15, ITSN1, Sgip1/AP2, synaptojanin1 interactome by Mishra, R., Sengül, G. F., Candiello, E., Schu, P.

“…The AP1/σ1B knockout causes impaired synaptic vesicle recycling and enhanced protein sorting into endosomes, leading to severe intellectual disability. These…”
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Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting by Schu, P.V. (University of California at San Diego), Takegawa, K, Fry, M.J, Stack, J.H, Waterfield, M.D, Emr, S.D

“…The VPS34 gene product (Vps34p) is required for protein sorting to the lysosome-like vacuole of the yeast Saccharomyces cerevisiae. Vps34p shares significant…”
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Vesicular protein transport by SCHU, P

“…Protein transport and sorting in the secretory and endocytic pathways via vesicles is required for organelle biogenesis, constitutive and regulated secretion…”
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membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole by Stack, J.H, Herman, P.K, Schu, P.V, Emr, S.D

“…The Vps15 protein kinase and the Vps34 phosphatidylinositol 3-kinase (PI 3-kinase) are required for the sorting of soluble hydrolases to the yeast vacuole…”
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A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins by Burd, Christopher G., Mustol, Peggy A., Schu, Peter V., Emr, Scott D.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The motif EXEXXXL in the cytosolic tail of the secretory human proprotein convertase PC7 regulates its trafficking and cleavage activity by Durand, Loreleï, Duval, Stéphanie, Evagelidis, Alexandra, Guillemot, Johann, Dianati, Vahid, Sikorska, Emilia, Schu, Peter, Day, Robert, Seidah, Nabil G.

“…Many secretory proteins are activated by cleavage at specific sites. The proprotein convertases (PCs) form a family of nine secretory subtilisin-like serine…”
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Import into and degradation of cytosolic proteins by isolated yeast vacuoles by Horst, M, Knecht, E C, Schu, P V

“…In eukaryotic cells, both lysosomal and nonlysosomal pathways are involved in degradation of cytosolic proteins. The physiological condition of the cell often…”
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mu 1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptors by Meyer, C, Zizioli, D, Lausmann, S, Eskelinen, E, Hamann, J, Saftig, P, Figura, Kv, Schu, P

“…The heterotetrameric AP-1 complex is involved in the formation of clathrin-coated vesicles at the trans-Golgi network (TGN) and interacts with sorting signals…”
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Cytosolic Hsp70s are involved in the transport of aminopeptidase 1 from the cytoplasm into the vacuole by Satyanarayana, Chitkala, Schröder-Köhne, Stephan, Craig, Elizabeth A., Schu, Peter V., Horst, Martin

“…Eukaryotic 70 kDa heat shock proteins (Hsp70s) are localized in various cellular compartments and exhibit functions such as protein translocation across…”
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Impaired Osteoclastic Bone Resorption Leads to Osteopetrosis in Cathepsin-K-Deficient Mice by Saftig, Paul, Hunziker, Ernst, Wehmeyer, Olaf, Jones, Sheila, Boyde, Alan, Rommerskirch, Winfried, Moritz, Jorg Detlev, Schu, Peter, Von Figura, Kurt

“…Cathepsin K is a recently identified lysosomal cysteine proteinase. It is abundant in osteoclasts, where it is believed to play a vital role in the resorption…”
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Clathrin Adaptor epsinR Is Required for Retrograde Sorting on Early Endosomal Membranes by Saint-Pol, Agnès, Yélamos, Belén, Amessou, Mohamed, Mills, Ian G, Dugast, Marc, Tenza, Danièle, Schu, Peter, Antony, Claude, McMahon, Harvey T, Lamaze, Christophe, Johannes, Ludger

“…Retrograde transport links early/recycling endosomes to the trans-Golgi network (TGN), thereby connecting the endocytic and the biosynthetic/secretory…”
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The proteinase yscA‐inhibitor, I A 3 , gene Studies of cytoplasmic proteinase inhibitor deficiency on yeast physiology by Schu, Peter, Wolf, Dieter H.

“…The gene of the proteinase yscA inhibitor I A 3 , , of the yeast Saccharamyces cerevisiae was isolated by oligonucleotide screening of a genomic DNA library…”
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A New Class of Mutants Deficient in Dodecamerization of Aminopeptidase 1 and Vacuolar Transport by Andrei-Selmer, Cornelia, Knüppel, Angelika, Satyanarayana, Chitkala, Heese, Claudia, Schu, Peter V.

“…Vacuolar aminopeptidase 1 is transported to the vacuole by cytoplasmic double-membrane vesicles, the nonclassic Cvt pathway. The cytosolic protein…”
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Distribution and Function of AP-1 Clathrin Adaptor Complexes in Polarized Epithelial Cells by Fölsch, Heike, Pypaert, Marc, Schu, Peter, Mellman, Ira

“…Expression of the epithelial cell-specific heterotetrameric adaptor complex AP-1B is required for the polarized distribution of many membrane proteins to the…”
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Vesicular protein transport by Schu, P

“…THE PHARMACOGENOMICS JOURNAL: (2002) 2, 69. DOI: 10.1038/sj.tpj.6500097…”
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Erratum: Vesicular protein transport by Schu, P

“…Correction to: The Pharmacogenomics Journal (2001) 1: 262–271 Due to a typesetting error, part of the text on page 263 of this article was unreadable. The…”
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Characterization of the in Vitro Retrograde Transport of MPR46 by Medigeshi, Guruprasad Ramarao, Schu, Peter

“…The mannose 6‐phosphate receptor MPR46 mediates sorting of lysosomal enzymes and recycles between the trans‐Golgi network and endosomes. We characterized the…”
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Early embryonic death of mice deficient in gamma-adaptin by Zizioli, D, Meyer, C, Guhde, G, Saftig, P, von Figura, K, Schu, P

“…Intracellular protein transport and sorting by vesicles in the secretory and endocytic pathways requires the formation of a protein coat on the membrane. The…”
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AP-1 and AP-3 Facilitate Lysosomal Targeting of Batten Disease Protein CLN3 via Its Dileucine Motif by Kyttälä, Aija, Yliannala, Kristiina, Schu, Peter, Jalanko, Anu, Luzio, J. Paul

“…CLN3 is a transmembrane protein with a predominant localization in lysosomes in non-neuronal cells but is also found in endosomes and the synaptic region in…”
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